Microbial Status and Genetic Evaluation of Mice and Rats
Proceedings of the 1999 US/Japan Conference
Published on 30. October 2000
Book
Paperback/Softback
166 pages
978-0-309-07195-6 (ISBN)
Description
US/Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US/Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes. In addition to these publications, the meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats. In cooperation with the Comparative Medicine section of NCRR/NIH, the ILAR Council and staff are pleased to become the host for this important annual meeting and look forward to participating in future meetings. The support and sponsorship of NCRR (P40 RR 11611) in the United States and the Central Institute for Experimental Animals in Japan are gratefully acknowledged.
Bringing together the leading scientists in the field of laboratory animal care has resulted in increased understanding of American and Japanese approaches to laboratory animal science and should continue to strengthen efforts to harmonize approaches aimed at resolving common challenges in the use of animal models for biomedical research and testing. This effort to improve understanding and cooperation between Japan and the United States should also be useful in developing similar interaction with other regions of the world including Europe, Australia, and Southeast Asia.
Bringing together the leading scientists in the field of laboratory animal care has resulted in increased understanding of American and Japanese approaches to laboratory animal science and should continue to strengthen efforts to harmonize approaches aimed at resolving common challenges in the use of animal models for biomedical research and testing. This effort to improve understanding and cooperation between Japan and the United States should also be useful in developing similar interaction with other regions of the world including Europe, Australia, and Southeast Asia.
More details
Language
English
Place of publication
Washington
United States
Target group
Professional and scholarly
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 229 mm
Width: 152 mm
ISBN-13
978-0-309-07195-6 (9780309071956)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
National Research Council | Institute for Laboratory Animal Research | International Committee of the
Microbial Status and Genetic Evaluation of Mice and Rats
Proceedings of the 1999 US/Japan Conference
E-Book
10/2000
1st Edition
National Academies Press
€96.99
Available for download
Content
Front Matter
Opening Remarks, Judith Vaitukaitis
Opening Remarks, Shin-Ichi Ota
Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results
Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards
Standardization of Rodent Health Surveillance: Regulation Versus Competition
Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals
Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and Mice
Emerging (and Reemerging) Viruses of Laboratory Mice and Rats
Emerging Infections as a Cause of Concern
Emerging Diseases in Mice and Rats
Survey of Heliobacter Species in Laboratory Mice and Gerbils in Japan
Genetic Evaluation of Outbred Rats
Genetic Evaluation of Outbred Rats from the Breeder's Perspective
Concept for Establishment of Rat Outbred Global Standard Strains
Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industry's Perspective
International Harmonization of Laboratory Animals
Rat Genetics and Toxicology
A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome
Evaluation of Targeted Mutations
Defining Behavioral Phenotypes in Transgenic and Knockout Mice
Defining Phenotype in Genetically Engineered Mice
Development of the Mouse Model Dramatype for Human Clinical Benefit
Concluding Remarks
Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic Functions
Concluding Comments, John Strandberg
Concluding Remarks, John Vandenbergh
Appendix A
Appendix B
Opening Remarks, Judith Vaitukaitis
Opening Remarks, Shin-Ichi Ota
Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results
Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards
Standardization of Rodent Health Surveillance: Regulation Versus Competition
Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals
Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and Mice
Emerging (and Reemerging) Viruses of Laboratory Mice and Rats
Emerging Infections as a Cause of Concern
Emerging Diseases in Mice and Rats
Survey of Heliobacter Species in Laboratory Mice and Gerbils in Japan
Genetic Evaluation of Outbred Rats
Genetic Evaluation of Outbred Rats from the Breeder's Perspective
Concept for Establishment of Rat Outbred Global Standard Strains
Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industry's Perspective
International Harmonization of Laboratory Animals
Rat Genetics and Toxicology
A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome
Evaluation of Targeted Mutations
Defining Behavioral Phenotypes in Transgenic and Knockout Mice
Defining Phenotype in Genetically Engineered Mice
Development of the Mouse Model Dramatype for Human Clinical Benefit
Concluding Remarks
Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic Functions
Concluding Comments, John Strandberg
Concluding Remarks, John Vandenbergh
Appendix A
Appendix B