Neuroendocrine Perspectives
Published on 12. October 2011
Book
Paperback/Softback
XII, 178 pages
978-1-4612-8155-9 (ISBN)
Description
Neuroendocrine Perspectives, Volume 7, is part of an international book series designed to keep clinicians and researchers appraised of important trends and new data in basic and clinical neuroendocrinology.
It focuses on four very rapidly evolving major topics: - the role of dopaminergic regulation of the intermediate pituitary lobe in elucidating intracellular signal transaction pathways and other regulatory mechanisms involved in transsynaptic regulation of peptide biosynthesis, post-translational processing, and hormone secretion; - the physiological and clinical implications of corticotropin releasing factor for such areas as diagnosing Cushing's syndrome, defining the hypothalamic and pituitary origins of secondary adrenal insufficiency, and distinguishing Cushing's syndrome from psychiatric states associated with hypercortisolism; - the large number of neurotrophic factors that affect CNS neurons and of neurite promoting factors that modulate neuronal performance, with emphasis on their mechanisms of action and their possible therapeutic applications to peripheral neuropathies and central diseases; - and the many factors that regulate changes in female reproductive cycles during middle age, with careful distinction between neuroendocrine and ovarian components and special attention to the possible cause-and-effect relationship within the cascade of events resulting in acyclicity and infertility.
It focuses on four very rapidly evolving major topics: - the role of dopaminergic regulation of the intermediate pituitary lobe in elucidating intracellular signal transaction pathways and other regulatory mechanisms involved in transsynaptic regulation of peptide biosynthesis, post-translational processing, and hormone secretion; - the physiological and clinical implications of corticotropin releasing factor for such areas as diagnosing Cushing's syndrome, defining the hypothalamic and pituitary origins of secondary adrenal insufficiency, and distinguishing Cushing's syndrome from psychiatric states associated with hypercortisolism; - the large number of neurotrophic factors that affect CNS neurons and of neurite promoting factors that modulate neuronal performance, with emphasis on their mechanisms of action and their possible therapeutic applications to peripheral neuropathies and central diseases; - and the many factors that regulate changes in female reproductive cycles during middle age, with careful distinction between neuroendocrine and ovarian components and special attention to the possible cause-and-effect relationship within the cascade of events resulting in acyclicity and infertility.
More details
Series
Edition
Softcover reprint of the original 1st ed. 1989
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Research
Illustrations
XII, 178 p.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 11 mm
Weight
306 gr
ISBN-13
978-1-4612-8155-9 (9781461281559)
DOI
10.1007/978-1-4612-3554-5
Schweitzer Classification
Other editions
Additional editions
Eugenio E. Müller | Robert M. MacLeod
Neuroendocrine Perspectives
Book
06/1989
Springer
€117.69
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Content
Dopaminergic Regulation of the Intermediate Pituitary.- Dopaminergic Regulation of Intermediate Lobe Secretion.- Dopaminergic Regulation of POMC Gene Expression.- Dopaminergic Regulation of Post-Translational Processing.- Dopaminergic Regulation of Cellular and Subcellular Morphology.- Summary and Conclusion.- Corticotropin Releasing Factor (Hormone): Physiological and Clinical Implications.- Corticotropin Releasing Factor and the Stress Response.- Pharmacological, Pharmacokinetic and Hemodynamic Properties of Ovine and Human Corticotropin Releasing Factor in Nonhuman Primates and in Man.- The Ovine CRF Stimulation Test in the Differential Diagnosis of Cushing's Syndrome and Adrenal Insufficiency.- Ovine CRF Stimulation in Patients with Hypercortisolemic Psychiatric States.- Summary and Conclusions.- Factors Promoting the Growth and Regeneration of Neuronal Cells.- In Vitro Studies of Neuronotrophic and Neurite Promoting Factors.- Neuronotrophic Factors.- Neuronotrophic Factors Adressing CNS Neurons.- Neurite Promoting Factors.- Serum-Replacing, Chemically Defined Supplements for Neuronal Cells.- Agents Modulating Neuronotrophic Factor Performance.- Molecular Mechanisms of Neuronotrophic Action.- In Vivo Involvement of Neuronotrophic and Neurite Promoting Factors.- Aging of the Female Reproductive System: A Neuroendocrine Perspective.- Changes in the Length and Variability of Reproductive Cycles.- Changes in Ovarian Function with Age.- Changes in Neuroendocrine Function with Age.