Biology for the AP (R) Course
Description
Biology for the AP® Course, Second Edition is the only major AP® Biology program built entirely for the AP® course. Unlike college texts adapted for high school, this text was written from the ground up to align with the latest 2025-2026 Course and Exam Description (CED), support the Big Ideas, and meet the needs of AP® students and teachers alike.
This trusted second edition adds even more AP® practice questions, new Unit-Opening Essays, a full Unit 0 on foundational skills, and end-of-unit Illustrative Examples that connect concepts to real-world science. The highly readable text balances accessibility with rigor-carefully scaffolding learning to help all students succeed with college-level biology.
Throughout the program, science practices are seamlessly integrated into the student friendly narrative along with visuals, activities, and assessments, helping students build the skills they need for the exam and beyond. Every element-from the AP® Exam Tips to the in-text tutorials and Practicing Science boxes-was crafted by a team of AP® experts, including former Chief Readers and longtime educators.
With powerful digital tools in Achieve-including assignable assessments, adaptive quizzing, and rich media like animations, simulations, and podcasts-this program equips teachers to deliver a complete, engaging, and effective AP® Biology experience.
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Content
Unit 0: Foundations
Module 01: Four Core Concepts of Biology
Module 02: Scientific Inquiry
Module 03: Visual Representations
Tutorial 1: Graphing
Illustrative Example: The Extinction of the Dinosaurs
Unit 1: Chemistry of Life
Module 1: Elements of Life
Module 2: Structure of Water and Hydrogen Bonding
Module 3: Carbohydrates and Lipids
Module 4: Nucleic Acids
Module 5: Proteins
Tutorial 2: Statistics
Illustrative Example: Luck and Penicillin
Unit 1 AP Practice Questions
Unit 2: Cells
Module 6: An Introduction to the Cell
Module 7: Cell Structure and Function
Module 8: Cell Size
Module 9: Plasma Membrane
Module 10: Mechanisms of Membrane Transport
Module 11: Osmosis, Tonicity, and Osmoregulation
Module 12: Origin of Compartmentalization and the Eukaryotic Cell
Illustrative Example: Plant-Fungal Associations
Unit 2 AP Practice Questions
Unit 3: Cellular Energetics
Module 13: Cellular Energy
Module 14: Enzymes and Environmental Impact on Enzyme Function
Module 15: Photosynthesis I: Overview
Module 16: Photosynthesis II: Biochemistry and Evolution
Module 17: Cellular Respiration I: Overview
Module 18: Cellular Respiration II: Biochemistry
Illustrative Example: A Photosynthetic Salamander
Unit 3 AP Practice Questions
Unit 4: Cell Communication and Cell Cycle
Module 19: Cell Communication
Module 20: Introduction to Signal Transduction
Module 21: Signal Transduction Pathways
Module 22: Feedback
Module 23: Cell Cycle
Module 24: Regulation of Cell Cycle
Illustrative Example: Cell Signaling and Cancer
Unit 4 AP Practice Questions
Unit 5: Heredity
Module 25: Meiosis and Genetic Diversity
Module 26: Mendelian Genetics
Tutorial 3: Probability
Module 27: Non-Mendelian Genetics
Module 28: Environmental Effects on Phenotypes
Illustrative Example: Living in a Lonely and Scary World
Unit 5 AP Practice Questions
Unit 6: Gene Expression and Regulation
Module 29: DNA and RNA Structure and Function
Module 30: DNA Replication
Module 31: Transcription and RNA Processing
Module 32: Translation
Module 33: Regulation of Gene Expression
Module 34: Cell Specialization and Development
Module 35: Mutations
Module 36: Biotechnology
Illustrative Example: CRISPR Scissors
Unit 6 AP Practice Questions
Unit 7: Evolution and Natural Selection
Module 37: Introduction to Evolution and Natural Selection
Module 38: Natural and Artificial Selection
Module 39: Population Genetics
Module 40: Hardy-Weinberg Equilibrium
Module 41: Evidence of Common Ancestry and Evolution
Module 42: Continuing Evolution
Module 43: Phylogeny
Module 44: Speciation
Module 45: Variation in Populations
Module 46: Origins of Life on Earth
Illustrative Example: The Anthropocene
Unit 7 AP Practice Questions
Unit 8: Ecology
Module 47: Responses to the Environment
Module 48: Energy Flow through Ecosystems
Module 49: Population Ecology
Module 50: Effect of Density on Populations
Tutorial 4: Rate and Growth in Populations Ecology
Module 51: Community Ecology
Module 52: Biodiversity
Module 53: Disruptions in Ecosystems
Illustrative Example: Impacts of Salt on Freshwater Ecosystems
Unit 8 AP Practice Questions
Cumulative AP Biology Practice Exam
Enrichment Modules
Enrichment Module A: The Nervous, Endocrine, and Immune Systems
Enrichment Module B: Animal Sensory Systems
Enrichment Module C: Viruses
Glossary / Glosario
Answers to Concept Check, Review, and Tutorial Practice Questions
The Periodic Table of the Elements