Nanotoxicology
Characterization, Dosing and Health Effects
1st Edition
Published on 25. July 2007
Book
Hardback
392 pages
978-1-4200-4514-7 (ISBN)
Description
Nanomaterials - structures with characteristic dimensions between 1 and 100 nm -exhibit a variety of unique and tunable chemical and physical properties that have made engineered nanoparticles central components in an array of emerging technologies. The use of nanotechnology is increasing; however its potential adverse effects on human health are not well understood. In order to accurately conduct hazard assessments, scientists need to understand the broad concepts that apply to pathways of dermal, oral, and respiratory exposure. This title is designed to elucidate those concepts and to examine the interaction of nanomaterials with the biological system, including membrane transfer, screening methods, and impact on major organs.
More details
Language
English
Place of publication
New York
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Illustrations
17 s/w Tabellen, 23 s/w Photographien bzw. Rasterbilder, 54 s/w Abbildungen
23 Halftones, black and white; 17 Tables, black and white; 54 Illustrations, black and white
Dimensions
Height: 229 mm
Width: 152 mm
Weight
703 gr
ISBN-13
978-1-4200-4514-7 (9781420045147)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions
Book
03/2014
2nd Edition
CRC Press
€267.85
Article not available for order
Content
Preface. Nanotoxicology:Laying a firm Foundation for Sustainable Nanotechnologies. Carbon Nanotube Structures and Compositions: Implications for Toxicological Studies. Effect-Oriented Physico-chemical Characterization Methods of Nanomaterials. Physico-chemical Characteristics of Nanoparticles which Determine their Potential Toxicity. Exposure Assessment for Safe Nanotechnology. Biodistribution of Nanoparticles: Insights from Drug Delivery. Nanoparticle Interactions with Biological Membranes: A Proposed Physical Mechanism. Placental Biological Barrier Models for Evaluation of Nanoparticle Transfer. Pharmacokinetics of Nanomaterials. Estimating Nanoparticle Dose in Humans: Issues and Challenges. Dispersion of Nanoparticles in Pulmonary Surfactants for In Vitro Toxicity Studies: Lessons from Ultrafine Diesel Exhaust Particles and Fine Mineral Dusts. Gene-Cellular Interactions of Nanomaterials: Genotoxicity to Genomics. Effect of Carbon Nanotube Exposure on Keratinocyte Protein Expression. Critical Issues in the Evaluation of Possible Adverse Pulmonary Effects Resulting from Airborne Nanoparticles. Carbon Nanotube Exposure and a Risk for Cardiovascular Effects. Hemostatic and Thrombotic Effects of Particulate Exposure: Assessing the Mechanisms. Pulmonary and Cardiovascular Effects of Nanoparticles. Understanding the Potential Neurotoxicology of Nanoparticles. Dermal Effects of Nanomaterials. Toxicity of Nanoparticles in the Eye. Nanoparticle Interactions with Biological Systems and Subsequent Activation of Intracellular Signaling Mechanisms. Occurrences, Fate and Characterization of Nanoparticles in the Environment. Impact of Nanoparticles on Aquatic Organisms. The Environmental Implications of Nanomaterials. Nanotechnology and Toxicology: How Do We Move Forward?