
Poxviruses
Birkhäuser (Publisher)
Published on 22. November 2006
Book
Hardback
XX, 442 pages
978-3-7643-7556-0 (ISBN)
Description
The study of poxviruses has a long and distinguished history that includes Jenner's founding work on smallpox vaccination. In the more than 200 years since that time we have seen the remarkable eradication of smallpox. It is difficult to overstate the significance of that achievement. It not only removed a disease that must rate as one of humankind's greatest scourges, but also demonstrated the effectiveness of the general principle of vacci- tion in our battles against disease. This book begins with a review of smallpox and its causative agent, Variola virus. The vaccine used in the successful smallpox eradication c- paign, vaccinia virus, is reviewed in the following chapter that describes its origin and its use as a vaccine, as well as the current understanding of the molecular biology and pathogenesis of this virus. Vaccinia virus is the most intensively studied poxvirus and the descriptions of the biology of this virus are relevant to all vertebrate poxviruses. The eradication ofsmallpox has drawn attention to the potential threat posed by other orthopoxviruses that infect humans, particularly Monkeypox virus. A description of this virus is given in the third chapter. Jenner's ori- nal vaccine is believed to have been Cowpox virus and this virus is reviewed in the chapter by Essbauer and Meyer. Additional chapters are devoted to each of the recognized genera of the vertebrate poxviruses and a f- ther chapter describes the subfamily of poxviruses infecting invertebrates. Together these provide a comprehensive review of the poxvirus family.
More details
Series
Edition
2007 ed.
Language
English
Place of publication
Basel
Switzerland
Publishing group
Springer Basel
Target group
Professional and scholarly
Research
Illustrations
XX, 442 p.
Dimensions
Height: 241 mm
Width: 160 mm
Thickness: 31 mm
Weight
857 gr
ISBN-13
978-3-7643-7556-0 (9783764375560)
DOI
10.1007/978-3-7643-7557-7
Schweitzer Classification
Other editions
Additional editions

Andrew Mercer | Axel Schmidt | Olaf Weber
Poxviruses
E-Book
02/2007
1st Edition
Birkhäuser
€213.99
Available for download
Content
Genus Orthopoxvirus: Vaccinia virus.- Genus Orthopoxvirus: Variola virus.- Genus Orthopoxvirus: Monkeypox virus.- Genus Orthopoxvirus: Cowpox virus.- Genus Molluscipoxvirus.- Genus Yatapoxvirus.- Genus Parapoxvirus.- Genus Capripoxvirus.- Genus Leporipoxvirus.- Genus Suipoxvirus.- Genus Avipoxvirus.- Subfamily Entomopoxvirinae.- Immunomodulation by poxviruses.- Immunomodulation by inactivated Orf virus (ORFV) - therapeutic potential.- Recombinant poxvirus vaccines in biomedical research.- Orthopoxvirus vaccines and vaccination.- Poxvirus diagnostics.- Therapy of poxvirus infections.- Environmental resistance, disinfection, and sterilization of poxviruses.- Early disease management strategies in case of a smallpox outbreak.- Historic aspects and early smallpox management approaches in the New World.