Development and Evaluation of Coded Aperture Reconstruction Methods for Intraoperative Gamma Cameras

Intraoperative Gamma Cameras are becoming increasingly common for radio-guided surgery. Coded Aperture Imaging has been proposed as a collimation technique, because it offers a better trade-off between sensitivity and spatial resolution, but requires image reconstruction. Therefore, a Convolutional Encoder-Decoder Network was developed and quantitatively compared with analytical methods. Furthermore, 3D-localization of point-like sources was investigated.