Drugs & Behavior
International Edition
7th Edition
Published on 9. August 2012
Book
Paperback/Softback
432 pages
978-0-205-91370-1 (ISBN)
Description
-
An up-to-date overview of behavioral pharmacology.
Drugs & Behavior starts with descriptions of basic pharmacological concepts of drug administration and pharmacokinetics, research methodology including clinical trials, tolerance and withdrawal, drug conditioning, addiction processes, and the neuroscience of drug action. Each chapter applies these concepts to different classes of recreational and therapeutic drugs.
Each chapter also includes a section on the history of the drug class being described to place the drugs in their historical and social context. The text is written to be understandable to students without a background in pharmacology, neuroscience, or psychology.
Learning Goals
Upon completing this book, readers should be able to:
Understand the behaviors of people who use drugs as medicine and for recreation
Understand new trends and developments in pharmacology
Identify the subjective, behavioral, and neurological differences between the use of both classes of drug
An up-to-date overview of behavioral pharmacology.
Drugs & Behavior starts with descriptions of basic pharmacological concepts of drug administration and pharmacokinetics, research methodology including clinical trials, tolerance and withdrawal, drug conditioning, addiction processes, and the neuroscience of drug action. Each chapter applies these concepts to different classes of recreational and therapeutic drugs.
Each chapter also includes a section on the history of the drug class being described to place the drugs in their historical and social context. The text is written to be understandable to students without a background in pharmacology, neuroscience, or psychology.
Learning Goals
Upon completing this book, readers should be able to:
Understand the behaviors of people who use drugs as medicine and for recreation
Understand new trends and developments in pharmacology
Identify the subjective, behavioral, and neurological differences between the use of both classes of drug
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Previous edition
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08/2012
7th Edition
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Content
Found in this Section:
1. Brief Table of Contents
2. Full Table of Contents
1. BRIEF TABLE OF CONTENTS
Chapter 1 Some Basic Pharmacology
Chapter 2 Behavioral Analysis of Drug Effects
Chapter 3 How We Adapt To Drugs - Tolerance, Sensitization, and Expectation
Chapter 4 Neurophysiology, Neurotransmitters, and the Nervous System
Chapter 5 Substance Use and Addictive Disorders
Chapter 6 Alcohol
Chapter 7 Anxiolytics and sedative-hypnotics
Chapter 8 Tobacco and Nicotine
Chapter 9 Caffeine and the Methylxanthines
Chapter 10 Psychomotor Stimulants
Chapter 11 Opioids
Chapter 12 Antipsychotic Drugs
Chapter 13 Antidepressants
Chapter 14 Cannabis
Chapter 15 Hallucinogens, Phantasticants, and Club Drugs
2. FULL TABLE OF CONTENTS
Chapter 1: Some Basic Pharmacology
What Is A Drug?
Names of Drugs
Describing Dosages
Potency and Effectiveness
Primary Effects And Side Effects
Drug Interactions
Pharmacokinetics
Inhalation
Oral Administration
Transdermal Administration
Distribution of Drugs
Elimination
Combining Absorption and Excretion Functions
The Therapeutic Window
Chapter 2: Behavioral Analysis of Drug Effects
History of Behavioral Pharmacology
Research Design
Measuring Unconditioned Behavior of Nonhumans
Measuring Conditioned Behavior of Nonhumans
Measuring Behavior of Humans
Development and Testing of Psychotherapeutic Drugs
Chapter 3: How We Adapt To Drugs - Tolerance, Sensitization, and Expectation
Tolerance
Withdrawal
Conditioning of Drug Effects
Sensitization
Expectancy and Context
Chapter 4: Neurophysiology, Neurotransmitters, and the Nervous System
The Neuron
The Synapse
The Nervous System
Development Of The Nervous System and Potential For Disruption
Neurotransmitters
Brain Imaging of Drug Effects
Chapter 5: Substance Use and Addictive Disorders
Defining Addiction
History of Research on Drug Use and Addiction
Addiction as Physical Dependence
Modern Behavioral Explanations of Drug Use
The Neuroanatomy of Motivation and Reinforcement
What Happens During Addiction?
Incentive Sensitization Theory
Hedonic Dysregulation and Adaptation
Disruption of Brain Control Circuits
Treating Drug Addiction
Chapter 6: Alcohol
Source of Alcohol
Origin and History
Measuring Alcohol Levels in The Body
Route of Administration and Pharmacokinetics
Absorption
Distribution
Elimination
Neuropharmacology
Alcohol Antagonists
Effects of Alcohol
Effects on Human Behavior and Performance
Effects on the Behavior of Nonhumans
Discriminative Stimulus Properties
Tolerance
Withdrawal
Self-Administration in Nonhumans
Self-Administration in Humans
Alcoholism
Harmful Effects of an Acute Administration
Harmful Effects of Chronic Consumption
Benefits of Alcohol Consumption
Treatments
Chapter 7: Anxiolytics and sedative-hypnotics
The Nature and Neurophysiology of Anxiety
Introduction to Anxiolytics and Sedative-Hypnotics
History of Anxiolytic and Sedative-Hypnotic Drug Development
Neurophysiology
Route of Administration and Absorption
Distribution and Excretion
Effects on the Body
Effects on Behavior and Performance of Humans
Effects on Performance
Effects on the Behavior of Nonhumans
Discriminative Stimulus Properties
Tolerance
Withdrawal
Self-Administration in Humans
Self-Administration in Nonhumans
Harmful Effects
Treatment
Chapter 8: Tobacco and Nicotine
Preparations
Route of Administration
Distribution
Excretion
Neurophysiology
Effects of Nicotine
Effects on the Behavior and Performance of Humans
Effects on the Behavior of Nonhumans
Drug State Discrimination
Self-Administration in Humans
Harmful Effects
Treatments
Chapter 9: Caffeine and the Methylxanthines
Sources of Methylxanthines
History of Methylxanthine Use
Extent of Methylxanthine Use
Route of Administration
Absorption
Distribution
Excretion
Neurophysiology
Effects of Caffeine and the Methylxanthines
Discriminative Stimulus Properties
Withdrawal
Self-Administration in Nonhumans
Self-Administration in Humans
Harmful Effects
Beneficial Effects
Epilogue
Chapter 10: Psychomotor Stimulants
Sources
History
Routes of Administration and Absorption
Distribution
Excretion
Neurophysiology
Effects of Psychomotor Stimulants
Effects on the Behavior and Performance Of Humans
Effects on the Behavior of Nonhumans
Dissociation and Drug State Discrimination
Tolerance
Withdrawal
Self-Administration in Humans
Harmful Effects
Treatment
Chapter 11: Opioids
Origins and Sources of Opioids
History
Routes of Administration
Distribution
Excretion
Neurophysiology
Effects of Opioids
Effects on Human Behavior and Performance
Effects on the Behavior of Nonhumans
Drug State Discrimination
Tolerance
Self-Administration in Humans
Self-Administration in Nonhumans
Harmful Effects
Pharmacological Treatment of Opioid Addiction
Chapter 12: Antipsychotic Drugs
The Nature of Schizophrenia
Theories of Schizophrenia
Discovery of Antipsychotic Medications
Comparing Typical and Atypical Antipsychotics
Routes of Administration
Absorption and Distribution
Excretion
Effects of Antipsychotics
Effects on the Behavior and Performance of Humans
Effects on the Behavior of Nonhumans
Drug State Discrimination and Dissociation
Tolerance
Withdrawal
Self-Administration in Humans and Nonhumans
Harmful Effects
Other Therapeutic Effects of Antipsychotic Drugs
Chapter 13: Antidepressants
The Nature of Depression
Theories of Depression
History of Antidepressant Medications
Neurophysiology
Absorption
Distribution
Excretion
Effects of Antidepressants
Effects on the Behavior and Performance of Humans
Effects on the Behavior of Nonhumans
Discriminative Stimulus Properties
Tolerance
Withdrawal
Self-Administration in Humans and Nonhumans
Harmful Effects
Other Treatments for Depression
Chapter 14: Cannabis
History
The Cannabinoids
Absorption
Distribution
Excretion
Neuropharmacology
Effects of Cannabis
Effects on Behavior and Performance Of Humans
Effects on the Behavior Of Nonhumans
Dissociation
Drug State Discrimination
Tolerance
Withdrawal
Self-Administration in Humans and Nonhumans
Epidemiology
Harmful Effects
Chapter 15: Hallucinogens, Phantasticants, and Club Drugs
LSD and the Monoamine-Like Drugs
Ecstasy and Synthetic Mescaline-Like Drugs
Salvia
Dissociative Anesthetics: Phencyclidine and Ketamine
Dextromethorphan
GHB
Mephedrone
1. Brief Table of Contents
2. Full Table of Contents
1. BRIEF TABLE OF CONTENTS
Chapter 1 Some Basic Pharmacology
Chapter 2 Behavioral Analysis of Drug Effects
Chapter 3 How We Adapt To Drugs - Tolerance, Sensitization, and Expectation
Chapter 4 Neurophysiology, Neurotransmitters, and the Nervous System
Chapter 5 Substance Use and Addictive Disorders
Chapter 6 Alcohol
Chapter 7 Anxiolytics and sedative-hypnotics
Chapter 8 Tobacco and Nicotine
Chapter 9 Caffeine and the Methylxanthines
Chapter 10 Psychomotor Stimulants
Chapter 11 Opioids
Chapter 12 Antipsychotic Drugs
Chapter 13 Antidepressants
Chapter 14 Cannabis
Chapter 15 Hallucinogens, Phantasticants, and Club Drugs
2. FULL TABLE OF CONTENTS
Chapter 1: Some Basic Pharmacology
What Is A Drug?
Names of Drugs
Describing Dosages
Potency and Effectiveness
Primary Effects And Side Effects
Drug Interactions
Pharmacokinetics
Inhalation
Oral Administration
Transdermal Administration
Distribution of Drugs
Elimination
Combining Absorption and Excretion Functions
The Therapeutic Window
Chapter 2: Behavioral Analysis of Drug Effects
History of Behavioral Pharmacology
Research Design
Measuring Unconditioned Behavior of Nonhumans
Measuring Conditioned Behavior of Nonhumans
Measuring Behavior of Humans
Development and Testing of Psychotherapeutic Drugs
Chapter 3: How We Adapt To Drugs - Tolerance, Sensitization, and Expectation
Tolerance
Withdrawal
Conditioning of Drug Effects
Sensitization
Expectancy and Context
Chapter 4: Neurophysiology, Neurotransmitters, and the Nervous System
The Neuron
The Synapse
The Nervous System
Development Of The Nervous System and Potential For Disruption
Neurotransmitters
Brain Imaging of Drug Effects
Chapter 5: Substance Use and Addictive Disorders
Defining Addiction
History of Research on Drug Use and Addiction
Addiction as Physical Dependence
Modern Behavioral Explanations of Drug Use
The Neuroanatomy of Motivation and Reinforcement
What Happens During Addiction?
Incentive Sensitization Theory
Hedonic Dysregulation and Adaptation
Disruption of Brain Control Circuits
Treating Drug Addiction
Chapter 6: Alcohol
Source of Alcohol
Origin and History
Measuring Alcohol Levels in The Body
Route of Administration and Pharmacokinetics
Absorption
Distribution
Elimination
Neuropharmacology
Alcohol Antagonists
Effects of Alcohol
Effects on Human Behavior and Performance
Effects on the Behavior of Nonhumans
Discriminative Stimulus Properties
Tolerance
Withdrawal
Self-Administration in Nonhumans
Self-Administration in Humans
Alcoholism
Harmful Effects of an Acute Administration
Harmful Effects of Chronic Consumption
Benefits of Alcohol Consumption
Treatments
Chapter 7: Anxiolytics and sedative-hypnotics
The Nature and Neurophysiology of Anxiety
Introduction to Anxiolytics and Sedative-Hypnotics
History of Anxiolytic and Sedative-Hypnotic Drug Development
Neurophysiology
Route of Administration and Absorption
Distribution and Excretion
Effects on the Body
Effects on Behavior and Performance of Humans
Effects on Performance
Effects on the Behavior of Nonhumans
Discriminative Stimulus Properties
Tolerance
Withdrawal
Self-Administration in Humans
Self-Administration in Nonhumans
Harmful Effects
Treatment
Chapter 8: Tobacco and Nicotine
Preparations
Route of Administration
Distribution
Excretion
Neurophysiology
Effects of Nicotine
Effects on the Behavior and Performance of Humans
Effects on the Behavior of Nonhumans
Drug State Discrimination
Self-Administration in Humans
Harmful Effects
Treatments
Chapter 9: Caffeine and the Methylxanthines
Sources of Methylxanthines
History of Methylxanthine Use
Extent of Methylxanthine Use
Route of Administration
Absorption
Distribution
Excretion
Neurophysiology
Effects of Caffeine and the Methylxanthines
Discriminative Stimulus Properties
Withdrawal
Self-Administration in Nonhumans
Self-Administration in Humans
Harmful Effects
Beneficial Effects
Epilogue
Chapter 10: Psychomotor Stimulants
Sources
History
Routes of Administration and Absorption
Distribution
Excretion
Neurophysiology
Effects of Psychomotor Stimulants
Effects on the Behavior and Performance Of Humans
Effects on the Behavior of Nonhumans
Dissociation and Drug State Discrimination
Tolerance
Withdrawal
Self-Administration in Humans
Harmful Effects
Treatment
Chapter 11: Opioids
Origins and Sources of Opioids
History
Routes of Administration
Distribution
Excretion
Neurophysiology
Effects of Opioids
Effects on Human Behavior and Performance
Effects on the Behavior of Nonhumans
Drug State Discrimination
Tolerance
Self-Administration in Humans
Self-Administration in Nonhumans
Harmful Effects
Pharmacological Treatment of Opioid Addiction
Chapter 12: Antipsychotic Drugs
The Nature of Schizophrenia
Theories of Schizophrenia
Discovery of Antipsychotic Medications
Comparing Typical and Atypical Antipsychotics
Routes of Administration
Absorption and Distribution
Excretion
Effects of Antipsychotics
Effects on the Behavior and Performance of Humans
Effects on the Behavior of Nonhumans
Drug State Discrimination and Dissociation
Tolerance
Withdrawal
Self-Administration in Humans and Nonhumans
Harmful Effects
Other Therapeutic Effects of Antipsychotic Drugs
Chapter 13: Antidepressants
The Nature of Depression
Theories of Depression
History of Antidepressant Medications
Neurophysiology
Absorption
Distribution
Excretion
Effects of Antidepressants
Effects on the Behavior and Performance of Humans
Effects on the Behavior of Nonhumans
Discriminative Stimulus Properties
Tolerance
Withdrawal
Self-Administration in Humans and Nonhumans
Harmful Effects
Other Treatments for Depression
Chapter 14: Cannabis
History
The Cannabinoids
Absorption
Distribution
Excretion
Neuropharmacology
Effects of Cannabis
Effects on Behavior and Performance Of Humans
Effects on the Behavior Of Nonhumans
Dissociation
Drug State Discrimination
Tolerance
Withdrawal
Self-Administration in Humans and Nonhumans
Epidemiology
Harmful Effects
Chapter 15: Hallucinogens, Phantasticants, and Club Drugs
LSD and the Monoamine-Like Drugs
Ecstasy and Synthetic Mescaline-Like Drugs
Salvia
Dissociative Anesthetics: Phencyclidine and Ketamine
Dextromethorphan
GHB
Mephedrone