
Diabetes and Cancer
Epidemiological Evidence and Molecular Links.
S. Karger (Publisher)
1st Edition
Published on 12. August 2008
Book
Hardback
148 pages
978-3-8055-8640-5 (ISBN)
Article exhausted; check different version
Description
The interdisciplinary work revealing varied roles in biological processes of chronic diseases has led to a new field of research concerning common molecular and clinical features of chronic diseases. Epidemiological literature suggests an association between the history of metabolic syndrome/diabetes mellitus type 2 and the risk of developing a variety of cancers. This book, at the forefront of experimental and clinical research, is the first to highlight the common molecular links between these two diseases. These tight links indicate a complex interdependency between both diseases on a cellular and hormonal basis, which is influenced by a variety of aspects (e.g. nutritional, social and neuro-immunological factors). Special attention has been given to the fundamental role of the switch from oxidative phosphorylation to glycolysis of cancer cells - the Warburg effect. Offering insights into the interdisciplinary approaches of tomorrow, this publication will encourage endocrinologists, oncologists, diabetologists, general practitioners, diabetic nurses and students of life sciences working separately on various aspects of diabetes and cancer to come together and combine therapies and strategies.
More details
Series
Language
English
Place of publication
Basel
Switzerland
Publishing group
Karger, S
Target group
Professional and scholarly
Illustrations
11 farbige Abbildungen, 2 Tabellen
17 fig., 11 in color, 2 tab.
Weight
620 gr
ISBN-13
978-3-8055-8640-5 (9783805586405)
Schweitzer Classification
Persons
Content
Preface: Masur, K.; Thevenod, F.; Zanker, K.S.; Pathophysiology of Diabetes Mellitus Type 2: Role of Obesity, Insulin Resistance and [beta]-Cell Dysfunction: Thevenod, F.; In vivo [beta]-Cell Imaging in Diabetes, [beta]-Cell Hyperplasia, and Insulinoma: Gotthardt, M.; Behe, M.; Lasser, T.; Incretin-Based Therapies for the Treatment of Type 2 Diabetes - DPP-4 Inhibitors and Incretin Mimetics: Gallwitz, B.; Janus Face of Glucose and Glucose-Regulating Hormones: Masur, K.; Role of Glucose Metabolism in Carcinogenesis and Cancer Progression: Gatenby, R.A.; Glucose Transporters: Their Abnormalities and Significance in Type 2 Diabetes and Cancer: Schurmann, A.; The Epidemiologic Relationship between Diabetes and Cancer: Zanker, K.S.; Diabetes Mellitus and Breast Cancer: Wolf, I.; Rubinek, T.; Nutrition, Diabetes, and Cancer: LaValle, J.B.; Diabetes and Cancer: The Road Ahead: Masur, K.; Thevenod, F.; Zanker, K.S.; Subject Index.