Introduction to Modeling Biological Systems

The authors begin with simple examples and gradually add complexity. Each chapter focuses on one discipline, and begins each example with a brief overview of the biology, followed by presentation of the model with accompanying illustrations and flow chart, with a detailed discussion of results to illustrate key modeling concepts. The chapters cover a broad span of biological problems, including: pharmacokinetics, pharmacodynamics, circulation, biochemical switches, cell division, and synaptic transmission. The text provides a step-by-step practical introduction on How to Build a Model. Again, the level is suitable for students without advanced training in math, but provides enough depth to allow readers to emerge with the ability to build their own models. Non-technical presentation explicitly aimed at those without special math training. Uses Berkeley Madonna, the most user friendly, fast, and powerful modeling tool available. Elegantly elucidates key modeling principles through carefully explained examples. Examples taken from across biology, including immunology, cell biology, pharmacology, biochemistry, and neuroscience. Includes end of chapter exercises.