
Systems Biomedicine
Concepts and Perspectives
Academic Press
Published on 30. October 2009
Book
Hardback
448 pages
978-0-12-372550-9 (ISBN)
Description
Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems.
Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon.
Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon.
More details
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
College/higher education
Professional and scholarly
cell, molecular, and developmental biology, genetics/ genomics, mathematics, biotechnology, biological and chemical engineering, physiology, and bioinformatics researchers involved in systems biology studies; students of systems biology
Dimensions
Height: 229 mm
Width: 152 mm
Weight
980 gr
ISBN-13
978-0-12-372550-9 (9780123725509)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

E-Book
09/2009
Academic Press
€78.95
Available for download
Persons
Editor
Genome Institute of Singapore, Singapore
Massachusetts Institute of Technology, Cambridge, MA, USA
Content
I. Foundations of Systems Biology
Genomic Technologies for Systems Biology
Proteomic Technologies
II. Computational Modeling of Biological Systems
Dynamic Systems Analysis
Spatio-temoral Modeling of Cellular Systems
High-level modeling of biological networks
High-Performance Computing
Modeling Software
III. Network Biology
Protein Interaction Networks
Signaling Networks with Modeling Strategies
Protein networks in integrin-mediated adhesions
Network Imaging
RNAi networks
IV. Integrative Biology of Higher Biosystems
Signal Processing and Integration During Development
Systems Biology and Stem Cell Biology
Application of immunologic modeling in drug discovery and development
V. Systems Medicine Applications
Systems Pharmacology
Genomic Technologies for Systems Biology
Proteomic Technologies
II. Computational Modeling of Biological Systems
Dynamic Systems Analysis
Spatio-temoral Modeling of Cellular Systems
High-level modeling of biological networks
High-Performance Computing
Modeling Software
III. Network Biology
Protein Interaction Networks
Signaling Networks with Modeling Strategies
Protein networks in integrin-mediated adhesions
Network Imaging
RNAi networks
IV. Integrative Biology of Higher Biosystems
Signal Processing and Integration During Development
Systems Biology and Stem Cell Biology
Application of immunologic modeling in drug discovery and development
V. Systems Medicine Applications
Systems Pharmacology