
DNA-encoded Library Technology for Drug Discovery
Royal Society of Chemistry (Publisher)
1st Edition
Published on 21. February 2025
Book
Hardback
166 pages
978-1-78801-487-8 (ISBN)
Description
DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously.
This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies.
A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.
This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies.
A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.
More details
Series
Language
English
Place of publication
Cambridge
United Kingdom
Target group
College/higher education
Product notice
Unsewn / adhesive bound
Dimensions
Height: 234 mm
Width: 156 mm
Thickness: 11 mm
Weight
427 gr
ISBN-13
978-1-78801-487-8 (9781788014878)
DOI
10.1039/9781788016032
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Guansai Liu | Casey J. Krusemark | Jin Li
DNA-encoded Library Technology for Drug Discovery
E-Book
02/2025
1st Edition
Royal Society of Chemistry
€206.99
Available for download
Persons
Purdue University, USA
Editor
HitGen Inc., China
Purdue University, USA
HitGen Inc., China
Content
Overview of Affinity-based DEL Selections with Select Target Types and Achievements
Machine Learning with DEL Selection Data and for DEL design
One bead one compound (OBOC) DELs for Biochemical Screens
Live cell-based DEL Selections
On-DNA Medicinal Chemistry: Focused libraries, fragment expansion, and hit optimization
DELs with Covalent Warheads
Application of DELs for E3 Ligase Ligand and PROTAC development
Machine Learning with DEL Selection Data and for DEL design
One bead one compound (OBOC) DELs for Biochemical Screens
Live cell-based DEL Selections
On-DNA Medicinal Chemistry: Focused libraries, fragment expansion, and hit optimization
DELs with Covalent Warheads
Application of DELs for E3 Ligase Ligand and PROTAC development