Anticancer Drug Toxicity

Containing the latest findings on the toxicity of a wide range of chemotherapeutic agents, this up-to-the-minute reference offers expert analyses on the pharmacokinetic-pharmacodynamic and pharmacokinetic-toxicodynamic relationships of anticancer compounds.
Anticancer Drug Toxicity
explores therapeutic drug monitoring (TDM) as a method of maximizing the efficacy, and minimizing the dangers, of chemotherapy

presents a vast amount of clinical pharmacokinetic data on cytostatic drugs

offers a comprehensive classification of toxicity patterns associated with the use of cytotoxic drugs

analyzes the pharmacokinetics of alkylating agents, platinum compounds, anthracyclines, antimetabolites, semisynthetic podophyllotoxin- and camptothecin derivatives, mitotic inhibitors, and other cytotoxic agents

highlights the pharmacogenetics of 6-mercaptopurine and its clinical significance

explicates toxicity in relation to the lungs, kidneys, heart, and gonads

examines disorders caused by asparaginase preparations

reviews types of secondary malignancy such as leukemias, ovarian cancer, testicular cancer, breast cancer, secondary solid neoplasias, and Hodgkin's disease

clarifies the understanding of toxicity as a crucial element in supportive management of cancer therapy

and more!
An enormously practical guide for everyday clinical practice, as well as a source of inspiration for further research in the field, Anticancer Drug Toxicity is an invaluable reference for clinical and medical oncologists; hospital, industrial, and clinical pharmacologists and pharmacists; toxicologists; pharmaceutical chemists; radiologists; and graduate and medical school students in these disciplines.