On Continuous Magnetically Enhanced Centrifugation in Large Scale Downstream Processing of Bioproducts

The current thesis targets on the technical use of Magnetically Enhanced Centrifugation (MEC). Aim is the understanding of the mechanisms of particle transport out of the magnetic field by simulations of the phenomena, and the realization of MEC in a large scale. Industrial scale machines for batch-wise and continuous discharge were tested. The use of synthetic magnetic particles with functionalized surface allows the separation of non-magnetic matter.