Pain and Headache. (Formerly: Research and Clinical Studies in Headache) / The Initial Processing of Pain and Its Descending Control: Spinal and Trigeminal Systems
Published in 1992
Book
Hardback
XIV, 306 pages
978-3-8055-5569-2 (ISBN)
Description
This book is primarily concerned with the basic neurobiological mechanisms which mediate the sensory/discriminative aspects of pain. Pain is viewed as a specific sense, and the elements comprising this sensory system are described in physiological, anatomical and neurochemical terms. The types and response properties of primary afferent neurons involved in pain from the body and face are reviewed as well as their connections in the spinal cord and trigeminal nuclei. The neurophysiology and neuroanatomy of the spinal cord cells encoding pain are also discussed. A novel theory on the function of the trigeminal nuclear complex in intraoral pain is presented together with some previously unpublished data detailing the terminations of nociceptors from the face. Finally, a thorough review of the many higher brain centres which can control nociceptive inputs to many pain centres is provided with critical analyses of their importance during normal behaviour.
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Content
Introduction to "The Specificity Theory of Pain"; primary afferent neurons involved in nociception; trigeminal primary afferent receptors; organization of the spinal cord; spinal terminations of nociceptive primary afferent axons; the organization of nociceptive neurons in the spinal grey matter; nociceptive neural organization in the trigeminal nuclei; descending control of nociception.