
Top Drugs
Their History, Pharmacology, and Syntheses
Jie Jack Li(Author)
Oxford University Press Inc
Published on 10. September 2015
Book
Hardback
224 pages
978-0-19-936258-5 (ISBN)
Description
Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery.
Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.
Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.
Reviews / Votes
"This book will interest students and scientists in disciplines such as chemistry, biology, pharmacology, toxicology, clinical medicine, and biotechnology, as well as informed general audiences. Recommended." --CHOICEMore details
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Illustrations
332 line art
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 17 mm
Weight
499 gr
ISBN-13
978-0-19-936258-5 (9780199362585)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Person
Jie Jack Li is a medicinal chemist who worked at Bristol Myers Squibb. He is currently an associate professor at University of San Francisco. He is an expert on drug discovery, and has published several books on the subject, including Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry (Oxford University Press, 2014), Triumph of the Heart: The Story of Statins (Oxford University Press, 2009), and Modern Organic Synthesis in the Laboratory (Oxford University Press, 2007).
Content
Table of Contents ; CARDIOVASCULAR DRUGS ; Chapter 1 Atorvastatin Calcium (Lipitor) ; Chapter 2 Clopidogrel (Plavix) ; Chapter 3 Amlodipine (Novasc) ; CANCER DRUGS ; Chapter 4 Paclitaxel (Taxol) ; Chapter 5 Imatinib (Gleevec) ; DRUGS FOR METABOLIC DISEASES ; Chapter 6 Sitagliptin (Januvia) ; CNS DRUGS ; Chapter 7 Sertraline (Cymbalta) ; Chapter 8 Olanzapine (Zyprexa) ; DRUGS TO TREAT INFECTIOUS DISEASES ; Chapter 9 Sofosbuvir (Sovaldi) ; ULCER DRUGS ; Chapter 10 Esomeprazole (Nexium)

