Astrocytes in Psychiatric Disorders
Description
This contributed volume discusses the multiple roles of astrocytes, which determine the progression and outcome of neuropsychiatric diseases. This emerging area of study examines the ways in which astrocytes are involved in various aspects of disease initiation, progression and resolution. This monograph aims to integrate the body of information that has accumulated in recent years revealing the active role of astrocytes in neuropsychiatric pathology and in psychiatric disorders. Understanding roles of astrocytes in pathology will provide new targets for medical intervention and aid the development of much needed therapeutics. This book will be valuable for researchers and workers in the fields of neurobiology, neurology, and psychiatry, as well as fill the need for a textbook used in advanced courses/graduate seminars in glial pathophysiology.
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Persons
Vladimir Parpura is a Professor in the Department of Neurobiology at The University of Alabama in Birmingham, Alabama.
Alexei Verkhratsky is a Professor of Neurophysiology in the Faculty of Life Sciences at The University of Manchester in Manchester, United Kingdom.
Caterina Scuderi is an Assistant Professor in the Department of Physiology and Pharmacology at Sapienza University of Rome.
Baoman Li is a Professor at the Laboratory Teaching Center at the School of Forensic Medicine, China Medical University in Shenyang, China.
Content
Introduction: Neuroglia in psychiatric disorders
A. Verkhratsky, V. Parpura, B. Li & C. Scuderi
Part 1. General aspects of astrogliopathology with emphasis on neurocognitive disorders
Chapter 1. Astrocytes: The housekeepers and guardians of the CNS
A. Verkhratsky, V. Parpura, B. Li & C. Scuderi
Chapter 2. Principles of astrogliopathology
A. Verkhratsky, V. Parpura, B. Li & C. Scuderi
Chapter 3. Morphological appearance of astroglia in neuropsychiatric disorders
G. Rajkowska
Chapter 4. Astrocytes and neurotransmission: Glutamate and GABA in cognitive and mood disorders
Gerard Sanacora
Part 2. Astroglia in mood disorders
Chapter 5. Astroglia in bipolar disorder
A. M. Butt & A.D. Rivera
Chapter 6. Astroglia abnormalities in mood disorders
M.B. Cohen
Chapter 7. Astroglia in major depression and suicide
N. Mechawar
Part 3. Astroglia in Schizophrenia
Chapter 8. Neuroglia in Schizophrenia
S. Goldman & M.Nedergaard
Chapter 9. Glutamate turnover in Schizophrenia
R. McCullumsmith
Chapter 10. Astroglia and dopanime transmission in Schizophrenia
M. Pletnikov
Chapter 11. Kynurenic acid in Schyzophrenia
R. Schwarcz
Part 4. Astroglia in addictive disorders
Chapter 12. Astrocytes in addictive disorders
Peter Kalivas
Chapter 13. Astroglia in the vulnerability and maintenance of alcohol dependence
J. J. Miguel-Hidalgo
Part 5. Astroglia in anxiety and eating disorders
Chapter 14. Astroglia in response to stress
F.R. Walker
Chapter 15. Astroglia and Obsessive compulsive disorder
Kohichi Tanaka
Chapter 16. Astrocytes in regulation of food intake
Christina Garcia-Caceres / Y. Yang / T.L. Horvath H.
Chapter 17. Astrocytes in anorexia nervosa
J. Seitz
Part 6. Targeting astrocytes in therapeutic managemenet of neuropsychiatrioc disorders
Chapter 18. Astroglial serotonin receptors as the central target of classic antidepressants
Baoman Li & A. Verkhratsky
Chapter 19. Lithium targets astrocytes
Arthur Butt
Epilogue
A. Verkhratsky, V. Parpura, B. Li & C. Scuderi