Persister Cells and Infectious Disease
Published on 26. November 2019
Book
Hardback
X, 295 pages
978-3-030-25240-3 (ISBN)
Description
This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on studies that provide an understanding of the mechanisms of persister formation, antibiotic tolerance and role in disease, at the molecular level.
More details
Edition
2019 ed.
Language
English
Place of publication
Cham
Switzerland
Publishing group
Springer International Publishing
Target group
Professional and scholarly
Illustrations
28 farbige Abbildungen, 6 s/w Abbildungen
X, 295 p. 34 illus., 28 illus. in color.
Dimensions
Height: 241 mm
Width: 160 mm
Thickness: 23 mm
Weight
629 gr
ISBN-13
978-3-030-25240-3 (9783030252403)
DOI
10.1007/978-3-030-25241-0
Schweitzer Classification
Other editions
Additional editions
Kim Lewis
Persister Cells and Infectious Disease
Book
11/2020
Springer
€106.99
Shipment within 7-9 days
Kim Lewis
Persister Cells and Infectious Disease
E-Book
11/2019
1st Edition
Springer
€96.29
Available for download
Person
Professor Kim Lewis, Northeastern University Boston, Massachusetts, USA
Content
1. Evolution under antibiotic treatments: interplay between antibiotic persistence, tolerance and resistance.- 2. Antibiotic persisters and relapsing Salmonella enterica infections.- 3. The Biology of Persister Cells in E. coli.- 4. Persister Formation and Antibiotic Tolerance of Chronic Infections.- 5. Persister formation driven by TisB-dependent membrane depolarization.- 6. Toxin-antitoxin systems and persistence.- 7. Nutrient depletion and bacterial persistence.- 8. Genetic determinants of persistence in Escherichia coli.- 9. Persister resuscitation.- 10. Host-pathogen interactions influencing Mycobacterium tuberculosis persistence and drug tolerance.- 11. Drug susceptibility of individual mycobacterial cells.- 12. Antimicrobial drug discovery against persisters.