Inflammatory Processes:
Molecular Mechanisms and Therapeutic Opportunities
Published on 29. October 2012
Book
Paperback/Softback
XI, 144 pages
978-3-0348-9580-4 (ISBN)
Description
In November 1998 many of the key leaders of new drug discovery for
inflammatory diseases gathered at Hershey, Pennsylvania for the 9th
International Conference of the Inflammation Research Association. The
Conference was held over a five day period and provided a stimulating
environment for the open exchange of important advances in basic
inflammation research as well as new drug discovery and development.
This book encompasses some of the highlights of several presentations
made at the Conference. It contains some of the latest and important
developments in the field of inflammation research.
Topics include the status of eotaxin and chemokines in asthma and
allergy, signal transduction and regulation of diverse mediators such as
the JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well as
regulators of AP-1, macrophage metalloproteinases, lymphotoxin and
further insights into the role of MCP-1 in disease. Also discussed are
drug targets in rheumatoid and osteoarthritis, fibrotic diseases,...
More details
Series
Edition
Softcover reprint of the original 1st ed. 2000
Language
English
Place of publication
Basel
Switzerland
Publishing group
Springer Basel
Target group
Professional and scholarly
Professional/practitioner
Illustrations
XI, 144 p.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 9 mm
Weight
254 gr
ISBN-13
978-3-0348-9580-4 (9783034895804)
DOI
10.1007/978-3-0348-8468-6
Schweitzer Classification
Other editions
Additional editions
L. Gordon Letts | Douglas W. Morgan
Inflammatory Processes:
Molecular Mechanisms and Therapeutic Opportunities
Book
06/2000
1st Edition
Springer
€85.55
Article exhausted; check different version
Content
The role of eotaxin and related CC-chemokines in asthma and allergy.- Signal transduction by the JNK group of MAP kinases.- Cellular signaling to NF-?B: Role in inflammation and therapeutic promise.- Small molecule regulators of AP-1 and NF-?B.- Mammalian target of rapamycin: Immunosuppressive drugs offer new insights into cell growth regulation.- Constitutive expression of a tumor suppressor leads to tumor regression in a xenograft model.- Macrophage metalloproteinases in destructive inflammatory diseases.- Lymphotoxin in inflammation and lymphoid organ development: Variations on a theme.- Chemokine/cytokine biology during the evolution of fibrotic disease.- The role of MCP-1 in disease.- The role of chemokines in allergic diseases of the airways.- Ninth International Conference of the Inflammation Research Association, November 1-5, 1998: Summaries of workshops and poster discussions.- Targets in rheumatoid and osteoarthritis.- Signal transduction and regulation of gene expression.- Mediators of inflammation and their enzymes.- Cell adhesion molecules and leukocyte trafficking.- Pulmonary inflammation, fibrosis, and disease.- Angiogenesis, wound repair and skin inflammation.