Principles of Tissue Engineering
3rd Edition
Published on 6. September 2007
Book
Hardback
1344 pages
978-0-12-370615-7 (ISBN)
Description
First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.
More details
Edition
3rd edition
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Basic and clinical researchers in fields such as biology, chemistry, materials science, and engineering with an interest in tissue engineering.
Edition type
New edition
Dimensions
Height: 279 mm
Width: 216 mm
Weight
2970 gr
ISBN-13
978-0-12-370615-7 (9780123706157)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
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Robert Lanza | Robert Langer | Joseph P. Vacanti
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Persons
Robert Lanza is an American scientist and author whose research spans the range of natural science, from biology to theoretical physics. TIME magazine recognized him as one of the "100 Most Influential People in the World,? and Prospect magazine named him one of the Top 50 "World Thinkers.? He has hundreds of scientific publications and over 30 books, including definitive references in the fields of stem cells, tissue engineering, and regenerative medicine. He's a former Fulbright Scholar and studied with polio-pioneer Jonas Salk and Nobel laureates Gerald Edelman (known for his work on the biological basis of consciousness) and Rodney Porter. He also worked closely (and co-authored papers in Science on self-awareness and symbolic communication) with noted Harvard psychologist BF Skinner. Dr. Lanza was part of the team that cloned the world's first human embryo, the first endangered species, and published the first-ever reports of pluripotent stem cell use in humans. Robert Langer received honorary doctorates from the ETH (Switzerland) in 1996 and the Technion (Israel) in 1997. Dr. Langer is the Kenneth J. Germeshausen Professor of Chemical and Biomedical Engineering at MIT. He received a Bachelor's Degree from Cornell University in 1970 and a Sc.D. from MIT in 1974, both in chemical engineering. Dr. Langer has written 590 articles, 400 abstracts, 350 patents, and has edited 12 books.Dr. Langer has received over 70 major awards, including the Gairdner Foundation International Award, the Lemelson-MIT prize, the American Chemical Society (ACS) Polymer Chemistry and Applied Polymer Science Awards, Creative Polymer Chemistry Award (ACS, Polymer Division), the Pearlman Memorial Lectureship Award (ACD, Biochemical Technology Division), and the A.I.Ch.E's Walker, Professional Progress, Bioengineering, and Stine Materials Science and Engineering Awards. In 1989, Dr. Langer was elected to the Institute of Medicine and the National Academy of Sciences, and in 1992 he was elected to both the National Academy of Engineering and to the National Academy of Sciences. He is the only active member of all 3 United States National Academies. Dr. Joseph P. Vacanti received his M.D. degree from the university of Nebraska in 1974. He received his training in general surgery at the Massachusetts General Hospital from 1974 through 1981 and in pediatric surgery at The Children's Hospital, Boston from 1981 through 1983. He then received clinical training in transplantation from the University of Pittsburgh. He spent two years in the laboratories of Dr. M. Judah Folkman working in the filed on angiogenesis from 1977 through 1979. Upon completion of his training, Dr. Vacanti joined the staff in surgery at children's Hospital in Boston and began clinical programs in pediatric liver transplantation and extracorporeal membrane oxygenation. In the laboratory, he continued studies in and began work in the filed of tissue engineering in 1985. Dr. Vacanti is now John Homans Professor of Surgery at Harvard Medical School, Visiting surgeon at Massachusetts General Hospital, director of the Wellman 6 Surgical laboratories, director of the Laboratory of Tissue Engineering and Organ Fabrication and Director of Pediatric Transplantation at Massachusetts General Hospital, Boston. He has authored more than 120 original reports, 30 book chapters, and 197 abstracts. He has more than 25 patents or patents pending in the United States, Europe, and Japan.
Content
INTRODUCTION TO TISSUE ENGINEERING
1. The History and Scope of Tissue Engineering
Joseph P. Vacanti and Charles A. Vacanti
2. The Challenge of Imitating Nature
Robert M. Nerem
3. Moving into the Clinic
Alan J. Russell and Timothy Bertram
4. Future Perspectives
Mark E. Furth and Anthony Atala
PART ONE: THE BASIS OF GROWTH AND DIFFERENTIATION
5. Molecular Biology of the Cell
Jonathan Slack
6. Organization of Cells into Higher-Ordered Structures
Jon D. Ahlstrom and Carol A. Erickson
7. Dynamics of Cell-ECM Interactions
M. Petreaca and Manuela Martins-Green
8. Matrix Molecules and Their Ligands
Bjorn Reino Olsen
9. Morphogenesis and Tissue Engineering
A.H. Reddi
10. Gene Expression, Cell Determination and Differentiation
William Nikovits, Jr. and Frank E. Stockdale
PART TWO: IN VITRO CONTROL OF TISSUE DEVELOPMENT
11. Engineering Functional Tissues
Lisa E. Freed and Farshid Guilak
12. Principles of Tissue Culture and Bioreactor Design
R.I. Freshney, B. Obradovic, W. Grayson, C. Cannizzaro and Gordana Vunjak-Novakovic
13. Regulation of Cell Behavior by Extracellular Proteins
Amy Bradshaw and E. Helene Sage
14. Growth Factors
Thomas F. Deuel and Yunchao Chang
15. Mechanochemical Control of Cell Fate Switching
Donald E. Ingber
PART THREE: IN VIVO SYNTHESIS OF TISSUES AND ORGANS
16. In Vivo Synthesis of Tissues and Organs
Brendan A. Harley and Ioannis V. Yannas
PART FOUR: MODELS FOR TISSUE ENGINEERING
17. Models as Precursors for Prosthetic Devices
Eugene Bell
18. Quantitative Aspects
Alan J. Grodzinsky, Roger D. Kamm, and Douglas A. Lauffenburger
PART FIVE: BIOMATERIALS IN TISSUE ENGINEERING
19. Micro-Scale Patterning of Cells and Their Environment
Xingyu Jiang, Shuichi Takayama, Robert G. Chapman, Ravi S. Kane and George M. Whitesides
20. Cell Interactions with Polymers
W. Mark Saltzman and Themis R. Kyriakides
21. Matrix Effects
Jeffrey A. Hubbell
22. Polymer Scaffold Fabrication
Matthew B. Murphy and Antonios G. Mikos
23. Biodegradable Polymers
James M. Pachence, Michael P. Bohrer and Joachim Kohn
24. Micro- and Nanofabricated Scaffolds
Christopher J. Bettinger, Jeffrey T. Borenstein and Robert Langer
25. Three-Dimensional Scaffolds
Ying Luo, George Engelmayr, Debra T. Auguste, Lino da Silva Ferreira, Jeffrey M. Karp, Rajiv Saigal and Robert Langer
PART SIX: TRANSPLANTATION OF ENGINEERED CELLS AND TISSUES
26. Tissue Engineering and Transplantation in the Fetus
Dario O. Fauza
27. Immunomodulation
Denise L. Faustman
28. Immunoisolation
Beth A. Zielinski and Michael J. Lysaght
29. Engineering Challenges in Immunobarrier Device Development
Amy S. Lewis and Clark K. Colton
PART SEVEN: STEM CELLS
30. Embryonic Stem Cells
Alan Trounson
31. Adult Epithelial Tissue Stem Cells
Christopher S. Potten and James W. Wilson
32. Embryonic Stem Cells as a Cell Source for Tissue Engineering
Ali Khademhosseini, Jeffrey M. Karp, Sharon Gerecht, Lino Ferreira, Gordana Vunjak-Novakovic and Robert Langer
33. Postnatal Stem Cells
Pamela Gehron Robey and Paulo Bianco
PART EIGHT: GENE THERAPY
34. Gene Therapy
Ronald G. Crystal and Stefan Worgall
35. Gene Delivery into Cells and Tissues
Ales Prokop and Jeffrey M. Davidson
PART NINE: BREAST
36. Breast Reconstruction
Lamont Cathey, Kuen Yong Lee, Walter D. Holder, David J. Mooney and Craig R. Halberstadt
PART TEN: CARDIOVASCULAR SYSTEM
37. Progenitor Cells and Cardiac Homeostasis
Annarosa Leri, Toru Hosoda, Marcello Rota, Claudia Bearzi, Konrad Urbanek, Roberto Bolli, Jan Kejstura and Piero Anversa
38. Cardiac-Tissue Engineering
M. Radisic, H. Park and G. Vunjak-Novakovic
39. Blood Vessels
Luke Brewster, Eric M. Brey and Howard P. Greisler
40. Heart Valves
Peter Marc Fong, Jason Park and Christopher Kane Breuer
PART ELEVEN: ENDOCRINOLOGY AND METABOLISM
41. Generation of Islets from Stem Cells
Bernat Soria, Abdelkrim Hmadcha, Francisco J. Bedoya and Juan R. Tejedo
42. Bioartificial Pancreas
Athanassios Sambanis
43. Engineering Pancreatic Beta-Cells
Hee-Sook Jun and Ji-Won Yoon
44. Thymus and Parathyroid Organogenesis
Craig Scott Nowell, Ellen Richie, Nancy Ruth Manley and Catherine Clare Blackburn
PART TWELVE: GASTROINTESTINAL SYSTEM
45. Adult Stem Cells in Normal Gastrointestinal Function and Inflammatory Disease
Mairi Brittan and Nicholas A. Wright
46. Alimentary Tract
Shaun M. Kunisaki and Joseph Vacanti
47. Liver Stem Cells
Eric Lagasse
48. Liver
Gregory H. Underhill, Salman R. Khetani, Alice A. Chen and Sangeeta N. Bhatia
PART THIRTEEN: HEMATOPOIETIC SYSTEM
49. Hematopoietic Stem Cells
Malcolm A.S. Moore
50. Red Blood Cell Substitutes
Thomas M. S. Chang
51. Lymphoid Cells
Una Chen
PART FOURTEEN: KIDNEY AND GENITOURINARY SYSTEM
52. Stem Cells in Kidney Development and Regeneration
Gregory R. Dressler
53. Renal Replacement Devices
H. David Humes
54. Genitourinary System
Anthony Atala
PART FIFTEEN: MUSCULOSKELETAL SYSTEM
55. Mesenchymal Stem Cells
Faye H. Chen, Lin Song, Robert L. Mauck, Wan-Ju Li and Rocky S. Tuan
56. Bone Regeneration
Chantal E. Holy, F. Jerry Volenec, Jeffrey Geesin and Scott P. Bruder
57. Bone and Cartilage Reconstruction
Wei Liu, Wenjie Zhang and Yilin Cao
58. Regeneration and Replacement of the Intervertebral Disc
Lori A. Setton, Lawrence J. Bonassar and Koichi Masuda
59. Articular Cartilage Injury
Joseph A. Buckwalter, J.L. Marsh, T. Brown, A. Amendola and J.A. Martin
60. Tendons and Ligaments
Francine Goulet, Lucie Germain, A. Robin Poole and Francois A. Auger
61. Mechanosensory Mechanisms in Bone
Upma Sharma, Antonios G. Mikos and Stephen C. Cowin
62. Skeletal-Tissue Engineering
Matthew D. Kwan, Derrick C. Wan and Michael T. Longaker
PART SIXTEEN: NERVOUS SYSTEM
63. Neural Stem Cells
Lorenz Studer
64. Brain Implants
Lars U. Wahlberg
65. Spinal Cord Injury
John W. McDonald and Daniel Becker
66. Protection and Repair of Audition
Richard Altschuler, Yehoash Raphael, David C. Martin, Jochen Schacht, David J. Anderson and Josef M. Miller
PART SEVENTEEN: OPHTHALMIC APPLICATIONS
67. Stem Cells in the Eye
Michael E. Boulton, Julie Albon and Maria B. Grant
68. Corneal-Tissue Replacement
Jeffrey W. Ruberti, James D. Zieske and Vickery Trinkaus-Randall
69. Vision Enhancement Systems
Gislin Dagnelie
PART EIGHTEEN: ORAL/DENTAL APPLICATIONS
70. Biological Tooth Replacement and Repair
Anthony J. (Tony) Smith and Paul T. Sharpe
71. Oral and Maxillofacial Surgery
Simon Young, Kyriacos A. Athanasiou, Antonios G. Mikos and Mark Eu-Kien Wong
72. Periodontal-Tissue Engineering
Hai Zhang, Hanson K. Fong, William V. Giannobile and Martha J. Somerman
PART NINETEEN: RESPIRATORY SYSTEM
73. Progenitor Cells in the Respiratory System
Valerie Besnard and Jeffrey A. Whitsett
74. Lungs
Anne E. Bishop and Julia A. Polak
PART TWENTY: SKIN
75. Cutaneous Stem Cells
George Cotsarelis
76. Wound Repair
Kaustabh Ghosh and Richard A.F. Clark
77. Bioengineered Skin Constructs
Vincent Falanga and Katie Faria
PART TWENTY-ONE: CLINICAL EXPERIENCE
78.Current State of Clinical Application
Shaun M. Kunisaki and Dario O. Fauza
79. Tissue-Engineered Skin Products
Jonathan Mansbridge
80. Tissue-Engineered Cartilage Products
David W. Levine
81. Tissue-Engineered Bone Products
John F. Kay
82. Tissue-Engineered Cardiovascular Products
Thomas Eschenhagen, Herrmann Reichenspurner and Wolfmram-Hubertus Zimmermann
83. Tissue-Engineered Organs
Steve J. Hodges and Anthony Atala
PART TWENTY-TWO: REGULATION AND ETHICS
84. The Tissue-Engineering Industry
Michael J. Lysaght, Elizabeth Deweerd and Ana Jaklenec
85. The Regulatory Path From Concept to Market
Kiki B. Hellman
86. Ethical Issues
Laurie Zoloth
Epilogue
Joseph P. Vacanti
1. The History and Scope of Tissue Engineering
Joseph P. Vacanti and Charles A. Vacanti
2. The Challenge of Imitating Nature
Robert M. Nerem
3. Moving into the Clinic
Alan J. Russell and Timothy Bertram
4. Future Perspectives
Mark E. Furth and Anthony Atala
PART ONE: THE BASIS OF GROWTH AND DIFFERENTIATION
5. Molecular Biology of the Cell
Jonathan Slack
6. Organization of Cells into Higher-Ordered Structures
Jon D. Ahlstrom and Carol A. Erickson
7. Dynamics of Cell-ECM Interactions
M. Petreaca and Manuela Martins-Green
8. Matrix Molecules and Their Ligands
Bjorn Reino Olsen
9. Morphogenesis and Tissue Engineering
A.H. Reddi
10. Gene Expression, Cell Determination and Differentiation
William Nikovits, Jr. and Frank E. Stockdale
PART TWO: IN VITRO CONTROL OF TISSUE DEVELOPMENT
11. Engineering Functional Tissues
Lisa E. Freed and Farshid Guilak
12. Principles of Tissue Culture and Bioreactor Design
R.I. Freshney, B. Obradovic, W. Grayson, C. Cannizzaro and Gordana Vunjak-Novakovic
13. Regulation of Cell Behavior by Extracellular Proteins
Amy Bradshaw and E. Helene Sage
14. Growth Factors
Thomas F. Deuel and Yunchao Chang
15. Mechanochemical Control of Cell Fate Switching
Donald E. Ingber
PART THREE: IN VIVO SYNTHESIS OF TISSUES AND ORGANS
16. In Vivo Synthesis of Tissues and Organs
Brendan A. Harley and Ioannis V. Yannas
PART FOUR: MODELS FOR TISSUE ENGINEERING
17. Models as Precursors for Prosthetic Devices
Eugene Bell
18. Quantitative Aspects
Alan J. Grodzinsky, Roger D. Kamm, and Douglas A. Lauffenburger
PART FIVE: BIOMATERIALS IN TISSUE ENGINEERING
19. Micro-Scale Patterning of Cells and Their Environment
Xingyu Jiang, Shuichi Takayama, Robert G. Chapman, Ravi S. Kane and George M. Whitesides
20. Cell Interactions with Polymers
W. Mark Saltzman and Themis R. Kyriakides
21. Matrix Effects
Jeffrey A. Hubbell
22. Polymer Scaffold Fabrication
Matthew B. Murphy and Antonios G. Mikos
23. Biodegradable Polymers
James M. Pachence, Michael P. Bohrer and Joachim Kohn
24. Micro- and Nanofabricated Scaffolds
Christopher J. Bettinger, Jeffrey T. Borenstein and Robert Langer
25. Three-Dimensional Scaffolds
Ying Luo, George Engelmayr, Debra T. Auguste, Lino da Silva Ferreira, Jeffrey M. Karp, Rajiv Saigal and Robert Langer
PART SIX: TRANSPLANTATION OF ENGINEERED CELLS AND TISSUES
26. Tissue Engineering and Transplantation in the Fetus
Dario O. Fauza
27. Immunomodulation
Denise L. Faustman
28. Immunoisolation
Beth A. Zielinski and Michael J. Lysaght
29. Engineering Challenges in Immunobarrier Device Development
Amy S. Lewis and Clark K. Colton
PART SEVEN: STEM CELLS
30. Embryonic Stem Cells
Alan Trounson
31. Adult Epithelial Tissue Stem Cells
Christopher S. Potten and James W. Wilson
32. Embryonic Stem Cells as a Cell Source for Tissue Engineering
Ali Khademhosseini, Jeffrey M. Karp, Sharon Gerecht, Lino Ferreira, Gordana Vunjak-Novakovic and Robert Langer
33. Postnatal Stem Cells
Pamela Gehron Robey and Paulo Bianco
PART EIGHT: GENE THERAPY
34. Gene Therapy
Ronald G. Crystal and Stefan Worgall
35. Gene Delivery into Cells and Tissues
Ales Prokop and Jeffrey M. Davidson
PART NINE: BREAST
36. Breast Reconstruction
Lamont Cathey, Kuen Yong Lee, Walter D. Holder, David J. Mooney and Craig R. Halberstadt
PART TEN: CARDIOVASCULAR SYSTEM
37. Progenitor Cells and Cardiac Homeostasis
Annarosa Leri, Toru Hosoda, Marcello Rota, Claudia Bearzi, Konrad Urbanek, Roberto Bolli, Jan Kejstura and Piero Anversa
38. Cardiac-Tissue Engineering
M. Radisic, H. Park and G. Vunjak-Novakovic
39. Blood Vessels
Luke Brewster, Eric M. Brey and Howard P. Greisler
40. Heart Valves
Peter Marc Fong, Jason Park and Christopher Kane Breuer
PART ELEVEN: ENDOCRINOLOGY AND METABOLISM
41. Generation of Islets from Stem Cells
Bernat Soria, Abdelkrim Hmadcha, Francisco J. Bedoya and Juan R. Tejedo
42. Bioartificial Pancreas
Athanassios Sambanis
43. Engineering Pancreatic Beta-Cells
Hee-Sook Jun and Ji-Won Yoon
44. Thymus and Parathyroid Organogenesis
Craig Scott Nowell, Ellen Richie, Nancy Ruth Manley and Catherine Clare Blackburn
PART TWELVE: GASTROINTESTINAL SYSTEM
45. Adult Stem Cells in Normal Gastrointestinal Function and Inflammatory Disease
Mairi Brittan and Nicholas A. Wright
46. Alimentary Tract
Shaun M. Kunisaki and Joseph Vacanti
47. Liver Stem Cells
Eric Lagasse
48. Liver
Gregory H. Underhill, Salman R. Khetani, Alice A. Chen and Sangeeta N. Bhatia
PART THIRTEEN: HEMATOPOIETIC SYSTEM
49. Hematopoietic Stem Cells
Malcolm A.S. Moore
50. Red Blood Cell Substitutes
Thomas M. S. Chang
51. Lymphoid Cells
Una Chen
PART FOURTEEN: KIDNEY AND GENITOURINARY SYSTEM
52. Stem Cells in Kidney Development and Regeneration
Gregory R. Dressler
53. Renal Replacement Devices
H. David Humes
54. Genitourinary System
Anthony Atala
PART FIFTEEN: MUSCULOSKELETAL SYSTEM
55. Mesenchymal Stem Cells
Faye H. Chen, Lin Song, Robert L. Mauck, Wan-Ju Li and Rocky S. Tuan
56. Bone Regeneration
Chantal E. Holy, F. Jerry Volenec, Jeffrey Geesin and Scott P. Bruder
57. Bone and Cartilage Reconstruction
Wei Liu, Wenjie Zhang and Yilin Cao
58. Regeneration and Replacement of the Intervertebral Disc
Lori A. Setton, Lawrence J. Bonassar and Koichi Masuda
59. Articular Cartilage Injury
Joseph A. Buckwalter, J.L. Marsh, T. Brown, A. Amendola and J.A. Martin
60. Tendons and Ligaments
Francine Goulet, Lucie Germain, A. Robin Poole and Francois A. Auger
61. Mechanosensory Mechanisms in Bone
Upma Sharma, Antonios G. Mikos and Stephen C. Cowin
62. Skeletal-Tissue Engineering
Matthew D. Kwan, Derrick C. Wan and Michael T. Longaker
PART SIXTEEN: NERVOUS SYSTEM
63. Neural Stem Cells
Lorenz Studer
64. Brain Implants
Lars U. Wahlberg
65. Spinal Cord Injury
John W. McDonald and Daniel Becker
66. Protection and Repair of Audition
Richard Altschuler, Yehoash Raphael, David C. Martin, Jochen Schacht, David J. Anderson and Josef M. Miller
PART SEVENTEEN: OPHTHALMIC APPLICATIONS
67. Stem Cells in the Eye
Michael E. Boulton, Julie Albon and Maria B. Grant
68. Corneal-Tissue Replacement
Jeffrey W. Ruberti, James D. Zieske and Vickery Trinkaus-Randall
69. Vision Enhancement Systems
Gislin Dagnelie
PART EIGHTEEN: ORAL/DENTAL APPLICATIONS
70. Biological Tooth Replacement and Repair
Anthony J. (Tony) Smith and Paul T. Sharpe
71. Oral and Maxillofacial Surgery
Simon Young, Kyriacos A. Athanasiou, Antonios G. Mikos and Mark Eu-Kien Wong
72. Periodontal-Tissue Engineering
Hai Zhang, Hanson K. Fong, William V. Giannobile and Martha J. Somerman
PART NINETEEN: RESPIRATORY SYSTEM
73. Progenitor Cells in the Respiratory System
Valerie Besnard and Jeffrey A. Whitsett
74. Lungs
Anne E. Bishop and Julia A. Polak
PART TWENTY: SKIN
75. Cutaneous Stem Cells
George Cotsarelis
76. Wound Repair
Kaustabh Ghosh and Richard A.F. Clark
77. Bioengineered Skin Constructs
Vincent Falanga and Katie Faria
PART TWENTY-ONE: CLINICAL EXPERIENCE
78.Current State of Clinical Application
Shaun M. Kunisaki and Dario O. Fauza
79. Tissue-Engineered Skin Products
Jonathan Mansbridge
80. Tissue-Engineered Cartilage Products
David W. Levine
81. Tissue-Engineered Bone Products
John F. Kay
82. Tissue-Engineered Cardiovascular Products
Thomas Eschenhagen, Herrmann Reichenspurner and Wolfmram-Hubertus Zimmermann
83. Tissue-Engineered Organs
Steve J. Hodges and Anthony Atala
PART TWENTY-TWO: REGULATION AND ETHICS
84. The Tissue-Engineering Industry
Michael J. Lysaght, Elizabeth Deweerd and Ana Jaklenec
85. The Regulatory Path From Concept to Market
Kiki B. Hellman
86. Ethical Issues
Laurie Zoloth
Epilogue
Joseph P. Vacanti