Natural Product Inspired Scaffolds
Description
The book explains the use of natural products as scaffolds in tissue engineering. It presents an introduction to the concept of natural product-based scaffolds and explores various fabrication strategies for their synthesis. The book highlights the wide range of applications of these scaffolds in tissue engineering, including their use in tissue regeneration, wound healing, plastic surgery, and breast reconstruction. Specific natural products, such as gums (xanthan, gellan, arabic, guar, ghatti gum), chitosan, collagen are discussed in separate chapters. In addition, various application of natural product loaded PCL and PLA scaffolds have also been discussed. Each chapter focuses on the application of these natural product based scaffolds and explores their potential in tissue engineering. It also covers specific applications of these scaffolds in tissue regeneration, including angiogenesis, bone, skin, and nerve tissue regeneration. The book addresses important considerations regarding the toxicity and regulatory aspects of natural product-based scaffolds and explores the challenges associated with their implementation and emphasizes the need for safety and compliance in their use. Overall, the book provides a comprehensive overview of the field. It serves as a valuable resource for researchers, scientists, and professionals in the field of tissue engineering.
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Dr. Mohit Kumar is an Assistant Professor at the Department of Mechanical Engineering, University Institute of Engineering, Gharaun, Mohali. He completed his graduation (B. Tech) from Kurukshetra University, Kurukshetra, Master of Technology in Mechanical Engineering (spl. Welding and Fabrication) from Sant Longowal Institute of Engineering and Technology (SLIET, Deemed University) and his PhD in Mechanical Engineering (polymer composites) from Thapar Institute of Engineering and Technology. In overall, he has secured 18+ lakhs INR fellowship (till march 2021) since 2014 that include MHRD fellowship in M. Tech and DAE-BRNS, BARC fellowship in sponsored project. He has secured Gold medal for his academic excellence in M.Tech. He has published over 14 peer-reviewed papers and book chapters (Research article - 12, Book Chapter - 2) in reputed international/national journals and books. Additionally, he is the editorial review board member of two international journals. His research activities have focussed on mechanical characterizations of polymer composite materials, the aging of FRP composites, and FEM. At present, his area of interest is on the natural composites derived from the natural polymers having application area in Tissue Engineering.
Dr. Deepika Kathuria is an Assistant Professor at University Center for Research and Development, Chandigarh University, Gharuan, Punjab, India. She completed her masters in pharmaceuticals and Doctorate in Pharmaceutical Sciences from National Institute of Pharmaceutical Education and Research, Mohali, India. She has published over 19 peer-reviewed papers in reputed international journals. She has various honors/Fellowship/Awards to her credit i.e. Award of INSPIRE fellowship (JRF) from DST, Award of INSPIRE fellowship (SRF) from DST, Bristol-Mayer Squibb fellowship (Merit-cum-topper scholarship during M.Pharm), Newton Bhabha Placement, DST-exchange programme. She does research in Organic Chemistry, Medicinal Chemistry, Analytical Chemistry, Natural Products, CADD. She has an exposure of medicinal plants, pharmaceuticals, and cosmeceuticals and thus she can bring together this multidisciplinary topic in an informative way.
Dr. Ajay Sharma is a Natural Product Chemist with strong Organic Chemistry, Photochemistry, Biochemistry, and Ethnobotany background. Presently, he is working as an Assistant Professor at the University Centre for Research and Development, Department of Chemistry, Chandigarh University, Mohali, India. He completed his Graduation (B.Sc. Medical) from Govt. College Hoshiarpur (affiliated to Panjab University, Chandigarh), Master's Degree in Organic Chemistry (Natural Products) from Punjab Agriculture University Ludhiana and his PhD (Organic Chemistry - Natural product) from SLIET (Sant Longowal Institute of Engineering & Technology, Deemed University) Punjab. He has published over 45 peer-reviewed papers and book chapters in reputed international/national journals and books. Presently, his five edited book are under production in different international publications. He has various honors/Fellowship/Awards to his credit i.e. Role of honor from PAU Ludhiana (2011), Merit-cum-topper scholarship during M.Sc. (PAU Ludhiana) (2009-10), MHRD fellowship Award for Ph.D (2012), Award of INSPIRE fellowship (JRF, 2013) from DST, Award of INSPIRE fellowship (SRF, 2015) from DST, 1st Prize in Poster Award at National Conference (NICS-2016) and Best Poster Award in (TSFS-2016). He does research in Organic Chemistry, Natural Products Chemistry, Photochemistry, Food Chemistry. His research activities have focused on isolation and characterization of bioactive extracts from traditional medicinal plants and evaluation of their biological potential. Currently, his research group at Chandigarh University is investigating the field of more environmentally friendly synthesis of metal nanoparticles and carbon nanodots using plant extracts/plant-based biomass followed by assessing their biological, catalytic, and sensing potential. Till date, he has successfully guided six M.Sc. dissertation students.
Content
Chapter 1_ Introduction to Natural Product Based Tissue Engineering.- Chapter 2_ Fabrication strategies for synthesis of natural product-based scaffold.- Chapter 3_ Applications of Natural Product based Scaffold in Tissue Engineering.- Chapter 4_ Natural Gums (Xanthan, Gellan, Arabic, Guar, Ghatti Gum, etc.) Based Bio-Scaffold and Their Application in Tissue Engineering.- Chapter 5_ Natural Product Loaded Chitosan and Collagen Based Bio-Scaffold and their Applications.- Chapter 6_ Natural Product-Loaded PCL and PLA-Based Bio-Scaffold and Their Applications.- Chapter 7_ Applications of Bio-Scaffolds in Plastic Surgery.- Chapter 8_ Bio-Scaffold and their Applications in Tissue Regeneration (Bone, Skin and Nerve Tissue Regeneration).- Chapter 9_ Applications of Natural Product Loaded Scaffold for Wound Healing.- Chapter 10_ Enhancing Breast Reconstruction with Bio-Scaffolds - A Supportive Approach for Optimal Outcomes.- Chapter 11_ Toxicological and regulatory aspects of natural product based bio-scaffold.