Biochemistry of Signal Transduction and Regulation
Published on 15. December 1999
Book
Hardback
XXII, 506 pages
978-3-527-29771-9 (ISBN)
Description
Intracellular signal transduction, regulation of cell activities, and tumor formation - how do they work? This question is of central importance in biochemical research. The 1990s have seen great progress in the understanding of the molecular basis of biological signal transduction, and many facts are known by every medicinal chemist, biochemist, and biologist. This book relates the observed biological phenomena to the underlying biological processes. The topics range from function, structure and integral construction of signalling pathways, including a detailed description of the various types of carriers, to regulation of the cell cycle, and the role of ion channels in signal transduction. Special emphasis is placed on oncogenesis and tumour suppressants. A comprehensive bibliography including review articles provides access to the primary literature on the subject.
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New editions
Gerhard Krauss
Biochemistry of Signal Transduction and Regulation
Book
08/2001
2nd Edition
Wiley-VCH
€79.00
Article exhausted; check for reprint
Gerhard Krauss
Biochemistry of Signal Transduction and Regulation
Book
12/2000
2nd Edition
Wiley-VCH
€191.89
Article is exhausted; no reprint
Persons
Content
Regulation of gene expression; regulation of enzyme activities; function and structure of signalling pathways; signal transduction through nuclear receptors; G-protein-coupled signal transduction pathways; intracellular signalling agents: "Second messenger"; ser/thr-specific protein kinases and protein phosphatases; signal transduction through transmembrane receptors with tyrosine-specific protein kinase activity; signal transduction through ras-proteins; intracellular signal transduction - protein kinase cascade of MAP-kinase pathways; membrane receptors with associated tyrosine-kinase activity; transmembrane receptors with intrinsic ser/thr-kinase activity and signal transduction in the "Two-Component Pathway"; integral construction, networks, and specifity of signalling pathways; regulation of the cell cycle; malfunction of signalling pathways and tumor formation - oncogenes and tumor suppressants; apoptosis; ion channels and signal transduction.