Introduction to the Cellular and Molecular Biology of Cancer
4th Edition
Published on 28. July 2005
Book
Hardback
549 pages
978-0-19-856853-7 (ISBN)
Description
This new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research:
Reviews / Votes
Review from previous edition This edition is highly recommended to students of cancer, whether they be medical or non-medical scientists, and will take its readers to the leading edge of cancer research ... admirable book. * The Bulletin of the Royal College of Pathologists * Successive editions of this book have mirrored developments in cancer research and this new edition continues to provide a short but comprehensive introduction to the initiation, development and treatment of cancer. * ASLIB Book Guide * The first two editions were good: now it is excellent ... everything is covered and relevant citations are given. Not only are important basic clinical and pathological issues covered, but so too are all the important areas of tumour biology and the molecular processes and genetics relevant to cancer ... I consider this an invaluable book ... I intend to advise all my new graduate students and post docs to buy, read, and study a copy ... masterfully edited and well-illustrated text. This book is great! If you are interested in cancer, buy a copy! * Peter A. Hall, Journal of Pathology * This is an excellent book ... As one who teaches cancer genetics among other things, I greatly welcome a source to which one can recommend students ... A fascinating read for everyone with an interest (morbid or not) in the subject. * Simon Baumberg, Univ. of Leeds, SGM Quarterly * This book will be much appreciated by newcomers to cancer biology and will provide a concise and thought-provoking review for experts in the field. * Stanley Zucker, The Quarterly Review of Biology, Vol 82 June 2007 * This is a superb introduction to cancer studies for clinicians and is difficult to fault ... this must be a bargain hard to beat. I strongly recommend this text for all involved in cancer studies and the care of patients with cancer. * Crispian Scully, Oral Oncology *More details
Edition
4th Revised edition
Language
English
Place of publication
Oxford
United Kingdom
Target group
Professional and scholarly
Edition type
Revised edition
Illustrations
numerous b/w line, 6 halftones; 6 full colour
Dimensions
Height: 254 mm
Width: 196 mm
Thickness: 33 mm
Weight
1260 gr
ISBN-13
978-0-19-856853-7 (9780198568537)
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Schweitzer Classification
Other editions
Additional editions
Margaret Knowles | Peter Selby
Introduction to the Cellular and Molecular Biology of Cancer
Book
07/2005
4th Edition
Oxford University Press
€69.33
Shipment within 15-20 days
Persons
Margaret Knowles is Professor of Experimental Cancer Research at the University of Leeds, and Associate Director of the Cancer Research UK Clinical Centre, also in Leeds.
Peter Selby is Professor of Cancer Medicine and Director of the National Cancer Research Network at the University of Leeds.
Peter Selby is Professor of Cancer Medicine and Director of the National Cancer Research Network at the University of Leeds.
Content
1. What is cancer? ; 2. The causes of cancer ; 3. Inherited susceptibility to cancer ; 4. DNA repair and cancer ; 5. Epigenetic events in cancer ; 6. Molecular cytogenetics of cancer ; 7. Oncogenes ; 8. Tumour suppressor genes ; 9. The cancer cell cycle ; 10. Cellular immortalization and telomerase activation in cancer ; 11. Growth factors and their signalling pathways in cancer ; 12. Apoptosis: molecular physiology and significance for cancer therapeutics ; 13. Mechanisms of viral carcinogenesis ; 14. Cytokines and cancer ; 15. Hormones and cancer ; 16. The spread of tumours ; 17. Angiogenesis ; 18. Stem cells, heamopoiesis, and leukaemia ; 19. Animal models of cancer ; 20. The immunology of cancer ; 21. The molecular pathology of cancer ; 22. From transcriptome to proteome ; 23. Local treatment of cancer ; 24. Chemotherapy ; 25. Radiotherapy and molecular radiotherapy ; 26. Monoclonal antibodies and therapy ; 27. Immunotherapy of cancer ; 28. Cancer gene therapy ; 29. Screening ; 30. Conclusions and prospects