Principles of Cellular Engineering
Understanding the Biomolecular Interface
Published on 18. January 2006
Book
Hardback
320 pages
978-0-12-369392-1 (ISBN)
Description
This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine.
More details
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Biomedical engineers, cell and molecular biologists, and graduate students in cell and tissue engineering
Illustrations
Approx. 100 illustrations (50 in full color)
Dimensions
Height: 260 mm
Width: 184 mm
Weight
930 gr
ISBN-13
978-0-12-369392-1 (9780123693921)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Person
Content
Partial Contents:
PART I. NEUTROPHIL ADHESION
Adhesion of flowing neutrophils to model vessel surfaces
Bond formation during cell compression
A flow chamber for capillary networks
Membrane dynamics during neutrophil recruitment
Hydrodynamic recruitment of cells to reactive surfaces
PART II: CELL-SUBSTRATE ADHESION
Cell tensegrity models and cell-substrate interactions
Use of hydrodynamic shear stress to analyze cell adhesion
Traction forces exerted by endothelial cells
Control of endothelial cell adhesion by mechanotransmission
PART III. ENGINEERED BIOMIMETIC SURFACES
Realistic atomistic modeling of protein adsorption to ceramic biomaterials
Cell responses to micro- and nano-topography
PART I. NEUTROPHIL ADHESION
Adhesion of flowing neutrophils to model vessel surfaces
Bond formation during cell compression
A flow chamber for capillary networks
Membrane dynamics during neutrophil recruitment
Hydrodynamic recruitment of cells to reactive surfaces
PART II: CELL-SUBSTRATE ADHESION
Cell tensegrity models and cell-substrate interactions
Use of hydrodynamic shear stress to analyze cell adhesion
Traction forces exerted by endothelial cells
Control of endothelial cell adhesion by mechanotransmission
PART III. ENGINEERED BIOMIMETIC SURFACES
Realistic atomistic modeling of protein adsorption to ceramic biomaterials
Cell responses to micro- and nano-topography