Programmed Cell Death in Cancer Progression and Therapy

Cell Death: History and Future.- Caspase Mechanisms.- The Mitochondrial Death Pathway.- Apoptotic Pathways in Tumor Progression and Therapy.- Therapeutic Targeting of Death Pathways in Cancer: Mechanisms for Activating Cell Death in Cancer Cells.- Overcoming Resistance to Apoptosis in Cancer Therapy.- Trail Receptors: Targets for Cancer Therapy.- Rational Design of Therapeutics Targeting the BCL-2 Family: Are Some Cancer Cells Primed for Death but Waiting for a Final Push?.- Autophagy and Tumor Suppression: Recent Advances in Understanding the Link between Autophagic Cell Death Pathways and Tumor Development.- Regulation of Programmed Cell Death by the P53 Pathway.- Regulation of Programmed Cell Death by NF-?B and its Role in Tumorigenesis and Therapy.- Targeting Proteasomes as Therapy in Multiple Myeloma.- Histone Deacetylase Inhibitors: Mechanisms and Clinical Significance in Cancer: HDAC Inhibitor-Induced Apoptosis.- RNA Interference and Cancer: Endogenous Pathways and Therapeutic Approaches.- Cancer Stem Cells and Impaired Apoptosis.