Continuous Renal Replacement Therapy
3rd Edition
Published on 15. October 2025
Book
Paperback/Softback
328 pages
978-0-19-774916-6 (ISBN)
Description
Continuous Renal Replacement Therapy (CRRT) is the standard of care for management of critically ill patients with acute renal failure. This guide provides concise, evidence-based, bedside guidance about this treatment modality, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice. Organized into sections on theory, practice, special situations, and organizational issues, this volume provides a complete view of CRRT theory and practice. Tables highlight key points, whilst key studies and trials are included in each chapter. The third edition includes a new chapter on net ultrafiltration rate, throughout updated content ensures terminology and nomenclature match current standards, and the most up-to-date information on newly developed CRRT machines.
More details
Series
Edition
3rd Revised edition
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Edition type
Revised edition
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 202 mm
Width: 125 mm
Thickness: 21 mm
Weight
350 gr
ISBN-13
978-0-19-774916-6 (9780197749166)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
John A. Kellum, MD, MCCM received his medical degree from the Medical College of Ohio. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure. He has authored more than 750 publications and has won several awards for teaching. He lectures widely and has given more than 500 seminars and invited lectures worldwide.
Rinaldo Bellomo is Professor of Intensive Care Medicine, University of Melbourne; Honorary Professor of Medicine, Monash University, Co-director of the Australian and New Zealand Intensive Care Research Centre, Director of Intensive Care Research at the Austin Hospital and Senior Research Advisor in Intensive Care Research at the Royal Melbourne Hospital. He has produced >1800 PubMed cited
publications, is the most published biomedical investigator in the history of Australian medicine and the most published intensive care investigator in the world.
Claudio Ronco is Director of the Department of Nephrology and Transplantation at the International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy. He has held positions as Director of the Renal Laboratory of research at the Renal Research Institute and Professor of Medicine at the Albert Einstein College of Medicine and Beth Israel Medical Centre of New York in 1999 and 2000. He has co-authored 1246 papers, 65 books and 86 book chapters and has delivered more than 750 lectures at international meetings and universities.
Rinaldo Bellomo is Professor of Intensive Care Medicine, University of Melbourne; Honorary Professor of Medicine, Monash University, Co-director of the Australian and New Zealand Intensive Care Research Centre, Director of Intensive Care Research at the Austin Hospital and Senior Research Advisor in Intensive Care Research at the Royal Melbourne Hospital. He has produced >1800 PubMed cited
publications, is the most published biomedical investigator in the history of Australian medicine and the most published intensive care investigator in the world.
Claudio Ronco is Director of the Department of Nephrology and Transplantation at the International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy. He has held positions as Director of the Renal Laboratory of research at the Renal Research Institute and Professor of Medicine at the Albert Einstein College of Medicine and Beth Israel Medical Centre of New York in 1999 and 2000. He has co-authored 1246 papers, 65 books and 86 book chapters and has delivered more than 750 lectures at international meetings and universities.
Editor
Distinguished Professor of Critical Care Medicine, Bioengineering and Clinical & Translational ScienceDistinguished Professor of Critical Care Medicine, Bioengineering and Clinical & Translational Science, University of Pittsburgh School of Medicine
Professor of Intensive CareProfessor of Intensive Care, The University of Melbourne
Director, Department of Nephrology, Dialysis, and TransplantationDirector, Department of Nephrology, Dialysis, and Transplantation, St. Bortolo Hospital
Content
Chapter 1: The critically ill patient with AKI
John A. Kellum and Aditya Uppalapati
Chapter 2: History and rationale for CRRT
Claudio Ronco and Ilona Bobek
Chapter 3: Terminology and Nomenclature
Thiago Reis, Claudio Ronco, Rinaldo Bellomo, and John A. Kellum
Chapter 4: Basic principles of solute transport
Claudio Ronco and Bill Clark
Chapter 5: Principles of fluid management in the ICU
Rinaldo Bellomo and Sean M. Bagshaw
Chapter 6: Indications, timing and patient selection
John A, Kellum, Ragavan Murugan, and Mitra Nadim
Chapter 7: Biomarkers
Lakhmir Chawla and Alexander Zarbock
Chapter 8: Extended indications
Rinaldo Bellomo Ian Baldwin
Chapter 9: Dose adequacy and assessment
Zaccaria Ricci, Thiago Reis, Claudio Ronco
Chapter 10: Acid-base and electrolytes
John A. Kellum
Chapter 11: Choosing a therapy
Jorge Cerda and Claudio Ronco
Chapter 12: Vascular access
Kai Singbartl and Alexander Zarbock
Chapter 13: The circuit and the prescription
Rinaldo Bellomo and Ian Baldwin
Chapter 14: The membrane: size and material
Claudio Ronco and Bill Clark
Chapter 15: Fluids
John A. Kellum and Paul Palevsky
Chapter 16: Net Ultrafiltration Rate
Ragavan Murugan, John A. Kellum, and Rinaldo Bellomo
Chapter 17: Alarms and troubleshooting
Zaccaria Ricci, Ian Baldwin, and Claudio Ronco
Chapter 18: Maintaining circuit patency
Ian Baldwin
Chapter 19: Anticoagulation
Rinaldo Bellomo and Ian Baldwin
Chapter 20: Regional Citrate Anticoagulation
Rinaldo Bellomo
Chapter 21: Drug dosing on CRRT
Sandra Kane-Gill
Chapter 22: Pediatrics
Dana Fuhrman and Michael L. Moritz
Chapter 23: Therapeutic plasma exchange
Joseph E. Kiss
Chapter 24: MARS
Rinaldo Bellomo
Chapter 25: Sorbents
Gonzalo Ramirez-Guerrero, Claudio Ronco, Thiago Reis, and Dehua Gong
Chapter 26: Hybrid therapies
Claudio Ronco
Chapter 27: Patient Care Quality and Teamwork
Kim Whiteman and Fred Tasota
Chapter 28: Starting a CRRT program
Jorge Cerda
Chapter 29: Billing and Reimbursement
Kevin Finkel
Chapter 30: Machines
Anna Lorenzin and Claudio Ronco
Chapter 31: QI (What can go wrong)
Rinaldo Bellomo and Ian Baldwin
Chapter 32: Training Education
Kim Whiteman and Ian Baldwin
John A. Kellum and Aditya Uppalapati
Chapter 2: History and rationale for CRRT
Claudio Ronco and Ilona Bobek
Chapter 3: Terminology and Nomenclature
Thiago Reis, Claudio Ronco, Rinaldo Bellomo, and John A. Kellum
Chapter 4: Basic principles of solute transport
Claudio Ronco and Bill Clark
Chapter 5: Principles of fluid management in the ICU
Rinaldo Bellomo and Sean M. Bagshaw
Chapter 6: Indications, timing and patient selection
John A, Kellum, Ragavan Murugan, and Mitra Nadim
Chapter 7: Biomarkers
Lakhmir Chawla and Alexander Zarbock
Chapter 8: Extended indications
Rinaldo Bellomo Ian Baldwin
Chapter 9: Dose adequacy and assessment
Zaccaria Ricci, Thiago Reis, Claudio Ronco
Chapter 10: Acid-base and electrolytes
John A. Kellum
Chapter 11: Choosing a therapy
Jorge Cerda and Claudio Ronco
Chapter 12: Vascular access
Kai Singbartl and Alexander Zarbock
Chapter 13: The circuit and the prescription
Rinaldo Bellomo and Ian Baldwin
Chapter 14: The membrane: size and material
Claudio Ronco and Bill Clark
Chapter 15: Fluids
John A. Kellum and Paul Palevsky
Chapter 16: Net Ultrafiltration Rate
Ragavan Murugan, John A. Kellum, and Rinaldo Bellomo
Chapter 17: Alarms and troubleshooting
Zaccaria Ricci, Ian Baldwin, and Claudio Ronco
Chapter 18: Maintaining circuit patency
Ian Baldwin
Chapter 19: Anticoagulation
Rinaldo Bellomo and Ian Baldwin
Chapter 20: Regional Citrate Anticoagulation
Rinaldo Bellomo
Chapter 21: Drug dosing on CRRT
Sandra Kane-Gill
Chapter 22: Pediatrics
Dana Fuhrman and Michael L. Moritz
Chapter 23: Therapeutic plasma exchange
Joseph E. Kiss
Chapter 24: MARS
Rinaldo Bellomo
Chapter 25: Sorbents
Gonzalo Ramirez-Guerrero, Claudio Ronco, Thiago Reis, and Dehua Gong
Chapter 26: Hybrid therapies
Claudio Ronco
Chapter 27: Patient Care Quality and Teamwork
Kim Whiteman and Fred Tasota
Chapter 28: Starting a CRRT program
Jorge Cerda
Chapter 29: Billing and Reimbursement
Kevin Finkel
Chapter 30: Machines
Anna Lorenzin and Claudio Ronco
Chapter 31: QI (What can go wrong)
Rinaldo Bellomo and Ian Baldwin
Chapter 32: Training Education
Kim Whiteman and Ian Baldwin