Basic Clinical Radiobiology
5th Edition
Published on 20. August 2018
Book
Hardback
350 pages
978-1-4441-7963-7 (ISBN)
Description
Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology.
Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer.
This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists.
Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer.
This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists.
Reviews / Votes
"...a valuable resource for more clinically minded individuals needing to know the basics of tissue and tumor response to a variety of radiation regimens."Robert J Griffin, PhD (University of Arkansas for Medical Sciences)
More details
Edition
5th edition
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
College/higher education
Professional and scholarly
Professional Reference
Illustrations
229 farbige Abbildungen
229 Illustrations, color
Dimensions
Height: 280 mm
Width: 210 mm
Weight
1300 gr
ISBN-13
978-1-4441-7963-7 (9781444179637)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions
Michael C. Joiner | Albert van der KogeJ. l
Basic Clinical Radiobiology
Book
01/2025
6th Edition
CRC Press
€298.50
Shipment within 10-20 days
Previous edition
Michael C. Joiner | Albert van der Kogel
Basic Clinical Radiobiology
Book
03/2009
4th Edition
Hodder Arnold
€83.13
Article exhausted; check for reprint
Persons
Michael Joiner: Professor of Radiobiology, Wayne State University, USA
Albert van der Kogel: Emeritus Professor of Radiobiology, Radboud University Nijmegen Medical Centre, The Netherlands; also Department of Human Oncology, University of Wisconsin, USA
Albert van der Kogel: Emeritus Professor of Radiobiology, Radboud University Nijmegen Medical Centre, The Netherlands; also Department of Human Oncology, University of Wisconsin, USA
Content
Introduction: The significance of radiobiology and radiotherapy for cancer treatment. Irradiation-induced damage and the DNA damage response. Cell death after irradiation: How, when and why cells die. Quantifying cell kill and cell survival. Radiation dose-response relationships. Linear energy transfer and relative biological effectiveness. Physics of radiation therapy for the radiobiologist. Tumour growth and response to radiation. Fractionation: The linear-quadratic approach. The linear-quadratic approach in clinical practice. Modified fractionation. Time factors in normal tissue responses to irradiation. The dose-rate effect. Pathogenesis of normal tissue side effects. Stem cells in radiotherapy. Normal tissue tolerance and the effect of dose inhomogeneities. The oxygen effect and therapeutic approaches to tumour hypoxia. The tumour microenvironment and cellular hypoxia responses. Combined radiotherapy and chemotherapy. Molecular targeted agents for enhancing tumour response. Biological individualisation of radiotherapy. Molecular image guided radiotherapy. Retreatment tolerance of normal tissues. Biological response modification of normal tissue reactions: Basic principles and pitfalls. Hadron therapy: The clinical aspects. Tissue response models. Second cancers after radiotherapy.