Metalloprotein Active Site Assembly
Will be published approx. on 6. October 2017
Book
Hardback
424 pages
978-1-119-15983-4 (ISBN)
Description
Summarizes the essential biosynthetic pathways for assembly of metal cofactor sites in functional metalloproteins
Metalloprotein Active Site Assembly focuses on the processes that have evolved to orchestrate the assembly of metal cofactor sites in functional metalloproteins. It goes beyond the simple incorporation of single metal ions in a protein framework, and includes metal cluster assembly, metal-cofactor biosynthesis and insertion, and metal-based post-translational modifications of the protein environments that are necessary for function. Several examples of each of these areas have now been identified and studied; the current volume provides the current state-of-the-art understanding of the processes involved.
An excellent companion to the earlier book in this series Metals in Cells--which discussed both the positive and negative effects of cellular interactions with metals--this comprehensive book provides a diverse sampling of what is known about metalloprotein active site assembly processes. It covers all major biological transition metal components (Mn, Fe, Co, Ni, Mo), as well as the other inorganic components, metal-binding organic cofactors (e.g., heme, siroheme, cobalamin, molybdopterin), and post-translationally modified metal binding sites that make up the patchwork of evolved biological catalytic sites. The book compares and contrasts the biosynthetic assembly of active sites involving all biological metals. This has never been done before since it is a relatively new, fast-developing area of research.
Metalloprotein Active Site Assembly is an ideal text for practitioners of inorganic biochemistry who are studying the biosynthetic pathways and gene clusters involved in active site assembly, and for inorganic chemists who want to apply the concepts learned to potential synthetic pathways to active site mimics.
More details
Series
Edition
1. Auflage
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Product notice
sewn/stitched
Cloth over boards
Dimensions
Height: 284 mm
Width: 221 mm
Thickness: 23 mm
Weight
1402 gr
ISBN-13
978-1-119-15983-4 (9781119159834)
Schweitzer Classification
Other editions
Additional editions
Michael K. Johnson | Robert A. Scott
Metalloprotein Active Site Assembly
E-Book
08/2017
Wiley
€169.99
Available for download
Michael K. Johnson | Robert A. Scott
Metalloprotein Active Site Assembly
E-Book
08/2017
Wiley
€169.99
Available for download
Persons
Editors
Michael K. Johnson, University of Georgia, Athens, GA, USA
Robert A. Scott, University of Georgia, Athens, GA, USA
Content
Contributors ix
Series Preface xiii
Volume Preface xv
Part 1: Assembly and Trafficking of Simple Fe-S Clusters 1
Nif System for Simple [Fe-S] Cluster Assembly in Nitrogen-Fixing Bacteria 3
Patricia C. Dos Santos and Dennis R. Dean
Iron-Sulfur Cluster Assembly in Bacteria and Eukarya using the ISC Biosynthesis Machinery 17
Sandrine Ollagnier de Choudens and Helene Puccio
The Suf System in Archaea, Bacteria, and Eukaryotic Organelles 37
Guangchao Dong, Savannah Witcher, F. Wayne Outten and Marinus Pilon
Roles of Class II Glutaredoxins in the Maturation of Fe-S Proteins 53
Jonathan Przybyla-Toscano, Thomas Roret, Jeremy Couturier and Nicolas Rouhier
Part 2: Assembly of Complex and Heterometallic Fe-S Cluster Active Sites 73
Nitrogenase Metallocluster Assembly 75
Nathaniel S. Sickerman, Lee A. Rettberg, Yilin Hu and Markus W. Ribbe
Metallocluster Assembly: Maturation of [FeFe]-Hydrogenases 93
Giorgio Caserta, Ludovic Pecqueur, Cecilia Papini and Marc Fontecave
CO Dehydrogenase and Acetyl-CoA Synthase 111
Holger Dobbek
Part 3: Assembly of Homometallic and Heterometalic Cu Cluster Active Sites 123
Assembly of Dinuclear Copper Center in Tyrosinases and Hemocyanins 125
Nobutaka Fujieda and Shinobu Itoh
Multicopper Oxidases 139
Daniel J. Kosman
Assembly of the Redox-Active Metal Centers of Cytochrome c Oxidase 157
Eva Nyvltova, Antoni Barrientos and Jonathan Hosler
CuA and CuZ Center Assembly in Nitrous Oxide Reductase 185
Sofia R. Pauleta and Isabel Moura
MoCu CO Dehydrogenase and its Active-Site Assembly 197
Frank Mickoleit
Part 4: Assembly of Homometallic and Heterometallic Mn Clusters 213
Homo- and Heterometallic Dinuclear Manganese Proteins: Active Site Assembly 215
Gustav Berggren, Daniel Lundin and Britt-Marie Sjoeberg
Biogenesis and Assembly of the CaMn4O5 Core of Photosynthetic Water Oxidases and Inorganic Mutants 233
Colin Gates, Gennady Ananyev and G. Charles Dismukes
Part 5: Assembly of Homometallic and Heterometallic Ni Clusters 249
Urease Activation 251
Robert P. Hausinger
Insights into [NiFe]-Hydrogenase Active Site Metallocluster Assembly 261
Robert Gary Sawers and Constanze Pinske
Part 6: Assembly of Cofactors for Binding Active-Site Metal Centers 273
Moco in Mo/W Enzymes 275
Silke Leimkuehler
Heme Biosynthesis 299
Amy E. Medlock and Harry A. Dailey
Siroheme Assembly and Insertion to Nitrite and Sulfite Reductase 315
M. Elizabeth Stroupe and Martin J. Warren
Biosynthesis of Coenzyme F430 and the Posttranslational Modification of the Active Site Region of Methyl-Coenzyme M Reductase 323
Steven O. Mansoorabadi, Kaiyuan Zheng and Phong D. Ngo
Coenzyme B12 Biosynthesis in Bacteria and Archaea 335
Theodoric A. Mattes, Jorge C. Escalante-Semerena, Evelyne Deery and Martin J. Warren
Crosslinked Cys-Tyr Free Radical Redox Cofactor 361
James W. Whittaker
Topaquinone Biogenesis and Lysyl Tyrosine Quinone Biogenesis in Cu Amine Oxidases 375
David M. Dooley, Doreen E. Brown and Eric M. Shepard
Index 389
Series Preface xiii
Volume Preface xv
Part 1: Assembly and Trafficking of Simple Fe-S Clusters 1
Nif System for Simple [Fe-S] Cluster Assembly in Nitrogen-Fixing Bacteria 3
Patricia C. Dos Santos and Dennis R. Dean
Iron-Sulfur Cluster Assembly in Bacteria and Eukarya using the ISC Biosynthesis Machinery 17
Sandrine Ollagnier de Choudens and Helene Puccio
The Suf System in Archaea, Bacteria, and Eukaryotic Organelles 37
Guangchao Dong, Savannah Witcher, F. Wayne Outten and Marinus Pilon
Roles of Class II Glutaredoxins in the Maturation of Fe-S Proteins 53
Jonathan Przybyla-Toscano, Thomas Roret, Jeremy Couturier and Nicolas Rouhier
Part 2: Assembly of Complex and Heterometallic Fe-S Cluster Active Sites 73
Nitrogenase Metallocluster Assembly 75
Nathaniel S. Sickerman, Lee A. Rettberg, Yilin Hu and Markus W. Ribbe
Metallocluster Assembly: Maturation of [FeFe]-Hydrogenases 93
Giorgio Caserta, Ludovic Pecqueur, Cecilia Papini and Marc Fontecave
CO Dehydrogenase and Acetyl-CoA Synthase 111
Holger Dobbek
Part 3: Assembly of Homometallic and Heterometalic Cu Cluster Active Sites 123
Assembly of Dinuclear Copper Center in Tyrosinases and Hemocyanins 125
Nobutaka Fujieda and Shinobu Itoh
Multicopper Oxidases 139
Daniel J. Kosman
Assembly of the Redox-Active Metal Centers of Cytochrome c Oxidase 157
Eva Nyvltova, Antoni Barrientos and Jonathan Hosler
CuA and CuZ Center Assembly in Nitrous Oxide Reductase 185
Sofia R. Pauleta and Isabel Moura
MoCu CO Dehydrogenase and its Active-Site Assembly 197
Frank Mickoleit
Part 4: Assembly of Homometallic and Heterometallic Mn Clusters 213
Homo- and Heterometallic Dinuclear Manganese Proteins: Active Site Assembly 215
Gustav Berggren, Daniel Lundin and Britt-Marie Sjoeberg
Biogenesis and Assembly of the CaMn4O5 Core of Photosynthetic Water Oxidases and Inorganic Mutants 233
Colin Gates, Gennady Ananyev and G. Charles Dismukes
Part 5: Assembly of Homometallic and Heterometallic Ni Clusters 249
Urease Activation 251
Robert P. Hausinger
Insights into [NiFe]-Hydrogenase Active Site Metallocluster Assembly 261
Robert Gary Sawers and Constanze Pinske
Part 6: Assembly of Cofactors for Binding Active-Site Metal Centers 273
Moco in Mo/W Enzymes 275
Silke Leimkuehler
Heme Biosynthesis 299
Amy E. Medlock and Harry A. Dailey
Siroheme Assembly and Insertion to Nitrite and Sulfite Reductase 315
M. Elizabeth Stroupe and Martin J. Warren
Biosynthesis of Coenzyme F430 and the Posttranslational Modification of the Active Site Region of Methyl-Coenzyme M Reductase 323
Steven O. Mansoorabadi, Kaiyuan Zheng and Phong D. Ngo
Coenzyme B12 Biosynthesis in Bacteria and Archaea 335
Theodoric A. Mattes, Jorge C. Escalante-Semerena, Evelyne Deery and Martin J. Warren
Crosslinked Cys-Tyr Free Radical Redox Cofactor 361
James W. Whittaker
Topaquinone Biogenesis and Lysyl Tyrosine Quinone Biogenesis in Cu Amine Oxidases 375
David M. Dooley, Doreen E. Brown and Eric M. Shepard
Index 389