GnRH Analogues in Prostatic Cancer: The Way Forward
4th Int. Symposium on GnRH Analogues in Cancer and Human Reproduction, Geneva, Februar 1996: Proceedings. "European Urology", Vol 30, Suppl. 1 (1996). Supplement Issue: Vol. 30, Suppl. 1 (1996): European Urology
Published on 23. October 1996
Book
Paperback/Softback
IV, 52 pages
978-3-8055-6368-0 (ISBN)
Description
The treatment of patients with metastatic carcinoma of the prostate poses a great challenge to urologists. Androgen ablation is still the basic therapy for advanced disease and can be achieved either surgically or chemically. In this setting GnRH agonists such as leuprorelin play an increasingly important role. One of the problems of androgen ablation is hormonal resistance, often occurring after 18-23 months, which necessitates second-line treatment of tumors. This publication discusses both current therapeutic issues and the urgent need for new, effective strategies to counteract this situation. Quality-of-life issues and the importance of epidemiological information are also given due consideration. This valuable exchange of information by experts in the field will be of interest to all clinicians and researchers concerned with advanced prostatic carcinoma.
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Content
Introduction, D. Jocham. Session 1: Prospective epidemiologic study of prostate cancer in Italy - preliminary results, A.V. Bono et al; Randomized open labelled comparative study of the efficacy, safety and tolerability of leuprorelin acetate 1M and 3M depot in patients with advanced prostatic cancer, H.W. Wechsel et al; Maximum androgen blockade in 1996, L. Boccon-Gibod; discussion. Session 2: Intermittent endocrine therapy of prostate cancer, U.W. Tunn; Effects of neoadjuvant androgen deprovation therapy on prostatic cancer, M. Polito et al; Treatment of hormone-refractory prostate carcinoma, G. Fournier; discussion. Session 3: Early versus delayed hormonal therapy in advanced prostate cancer, E. Mazeman, P. Bertrand; Quality of life in prostate cancer patients, S. Rocca Rossetti; discussion; summary, D. Jocham.