
Joint and Bone
From Bench to Bedside
Academic Press
Published on 2. February 2023
Book
Paperback/Softback
246 pages
978-0-323-91938-8 (ISBN)
Description
Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside.
Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases.
Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Product notice
Paperback (trade)
Unsewn / adhesive bound
Illustrations
30 illustrations (20 in full color); Illustrations
Dimensions
Height: 190 mm
Width: 234 mm
Thickness: 19 mm
Weight
520 gr
ISBN-13
978-0-323-91938-8 (9780323919388)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

E-Book
01/2023
Academic Press
€155.00
Available for download
Persons
Dr. Gemn Jiang is an Associate Professor at the Zhejiang University School of Medicine. Professor Jiang has committed himself to scientific research in the field of sports system injury and regeneration. He has identified a new tendon differentiation model and recovered new mechanisms of tendon differentiation, as well as fabricated a functional tendon scaffold. Based on this work, he gained YIA of the international tendon/ligament conference in 2010. He also gained the second prize of the Natural Science Award of ministry of education. Dr. Ahmed Hashash is currently Endowed Chair and Distinguished Professor at Elizabeth City State University, campus of the University of North Carolina (UNC). He received his PhD from Manchester University, UK. Dr. Hashash was a fellow of the California Institute of Regenerative Medicine (CIRM) and New York University Medical School (MSSM), USA. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at School of Medicine University of California, USA. Dr Hashash was Associate Professor of Biomedicine at the University of Edinburgh (UK) Zhejiang Intl. campus and Texas A &M University, USA from 2017 to 2025. He has published more than 40 papers in reputed international journals, 10 books with Elsevier and Springer and over 20 book chapters, and is serving as an editorial board member of repute.
Editor
Associate Professor, Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang, China
Endowed Chair, Distinguished Professor, University of North Carolina
Content
1. Cutting edge research on stem cell applications in joint and bone repair and regeneration
2. Stem Cell-Based Organoid culture system as innovative model of osteoarthritis and other joint/bone diseases
3. Contributions of stem cell engineering to new therapies of joint/bone diseases
4. Roles of innovative genome editing technologies (e.g. CRISPR/Cas9 systems) in stem cell engineering, rheumatic diseases and other joint/bone diseases
5. Preclinical and clinical applications of iPSC technology in modeling osteoarthritis pathologies and testing drugs
6. The gold standard iPSCs in cartilage, joint and bone repair and regeneration
7. Mesenchymal stem cell related therapies for cartilage, joint and bone diseases
8. Advances in animal models for joint and bone diseases
9. Novel Biomaterials for stem cell engineering and bone regeneration
10. General Discussion, Conclusion Remark and Future Direction
2. Stem Cell-Based Organoid culture system as innovative model of osteoarthritis and other joint/bone diseases
3. Contributions of stem cell engineering to new therapies of joint/bone diseases
4. Roles of innovative genome editing technologies (e.g. CRISPR/Cas9 systems) in stem cell engineering, rheumatic diseases and other joint/bone diseases
5. Preclinical and clinical applications of iPSC technology in modeling osteoarthritis pathologies and testing drugs
6. The gold standard iPSCs in cartilage, joint and bone repair and regeneration
7. Mesenchymal stem cell related therapies for cartilage, joint and bone diseases
8. Advances in animal models for joint and bone diseases
9. Novel Biomaterials for stem cell engineering and bone regeneration
10. General Discussion, Conclusion Remark and Future Direction