Bioorganic Synthesis
Essentials of Biocatalysis for Chemists
Wiley-VCH (Publisher)
Book
Paperback/Softback
350 pages
978-3-527-32072-1 (ISBN)
Description
Aimed at students and junior researchers, this comprehensive introduction to organic synthesis with biocatalysts contains a wealth of knowledge not found in any standard chemistry textbook. Ideal for coursework, including lab courses, in a one-semester course of bioorganic or organic synthesis, the book is divided into two parts. An introductory section covers the fundamentals of enzymatic catalysis and the general procedures of using enzymes in the organic-chemical laboratory, while the practical second part contains detailed protocols for more than 50 enzmye-catalysed organic syntheses. Each of the protocols has been thoroughly tested in the authors' laboratories and comes with a complete description, including equipment list, expected yield, and safety considerations.
The text is rounded off by descriptions and supplier information for all commonly used enzymes, enabling even those chemists without prior experience to start working immediately. With its broad coverage of biocatalytic reactions, this textbook is also perfectly suited for biotechnologists or chemical engineers in the booming field of "white biotechnology".
Discover the power of 'White Biotechnology' for organic synthesis! A comprehensive introduction to enzyme reactions together with more than 50 tried-and-tested general protocols contain all the know-how for successful organic biocatalysis.
The text is rounded off by descriptions and supplier information for all commonly used enzymes, enabling even those chemists without prior experience to start working immediately. With its broad coverage of biocatalytic reactions, this textbook is also perfectly suited for biotechnologists or chemical engineers in the booming field of "white biotechnology".
Discover the power of 'White Biotechnology' for organic synthesis! A comprehensive introduction to enzyme reactions together with more than 50 tried-and-tested general protocols contain all the know-how for successful organic biocatalysis.
More details
Language
English
Place of publication
Weinheim
Germany
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 240 mm
Width: 170 mm
ISBN-13
978-3-527-32072-1 (9783527320721)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Persons
Günter Jeromin studied Chemistry at the University of Heidelberg (Germany). After a post-doctoral term with G. Büchi at the MIT (Cambridge, USA) he accepted a position in the RD Department of Rütgers Organics. Since 1987 he is Professor of Organic and Bioorganic Chemistry at the University of Applied Sciences Aachen. He has authored two German language textbooks, one of which has also been published in an English edition.
Martin Bertau studied Chemistry at the University of Freiburg (Germany). After five years in industry at Rohner (Basel, Switzerland) he returned to academia and is now a Professor for Organic and Biochemistry at Dresden University of Technology.
Martin Bertau studied Chemistry at the University of Freiburg (Germany). After five years in industry at Rohner (Basel, Switzerland) he returned to academia and is now a Professor for Organic and Biochemistry at Dresden University of Technology.
Content
Introduction: Biotransformations in Chemistry
ENZYME CATALYSIS
Solubility and Bioavailability of Chemical Substrates
Oxidoreductases
Transferases
Hydrolases
Lyases
Isomerases
Ligases
Working up the Products
Analysis of the Products and Determination of Yield
Stereochemical Considerations
LABORATORY PROTOCOLS
50 Protocols for Enzymatic and Whole-Cell Biotransformations
Practical Hints
APPENDIX
Solutions to the Study Questions
Suppliers of Enzymes and Chemicals
Literature.
ENZYME CATALYSIS
Solubility and Bioavailability of Chemical Substrates
Oxidoreductases
Transferases
Hydrolases
Lyases
Isomerases
Ligases
Working up the Products
Analysis of the Products and Determination of Yield
Stereochemical Considerations
LABORATORY PROTOCOLS
50 Protocols for Enzymatic and Whole-Cell Biotransformations
Practical Hints
APPENDIX
Solutions to the Study Questions
Suppliers of Enzymes and Chemicals
Literature.