Pacemaker Acty & Intercellular Comm
1st Edition
Published on 6. February 1995
Book
Hardback
370 pages
978-0-8493-7669-6 (ISBN)
Description
The book focuses on enhancing our understanding of pacemaker systems and associated mechanisms of intercellular communication. Three different physiological systems are compared: the cadiac system, the ??cells of the pancreas, and the gastrointestinal tract. Experts in all three areas highlight the parallels and comparisons among the systems. Emphasis is placed on finding precise characteristics of all cell types involved in pacemaker activity. The interpretation of data on single isolated cells in light of tissue function receives thorough discussion. Ion channel characteristics involved in the generation of action potential and pacemaker components are described in detail. A fascinating but largely unexplored area is touched upon: the electrical and metabolic coupling of different cell types. A most valuable feature is that most investigators have explored a variety of techniques to examine cell function: patch clamp studies, intracellular voltage recording, intracellular calcium measurements, gap junction conductance measurements, dye spread techniques, and more. Various aspects of the molecular biology of gap junction and ion channels are explored.
More details
Language
English
Place of publication
Bosa Roca
United States
Publishing group
Taylor & Francis Inc
Target group
College/higher education
Professional and scholarly
Physiologists, biophysicists, all biologists, and biochemists.
Illustrations
4 s/w Tabellen
29 figs., 4 tabs.
Dimensions
Height: 235 mm
Width: 156 mm
Weight
695 gr
ISBN-13
978-0-8493-7669-6 (9780849376696)
Schweitzer Classification
Content
Introduction
Pacemaker Activity and Intercellular Communication: An Introduction to the Book, J.D. Huizinga
The Heart
Generation of Pacemaker Activity in Mammalian Sinoatrial Node, W.R. Giles
The Sinoatrial Node: Structure, Inhomogeneity, and Intercellular Interaction, L.N. Bouman and H.J. Jongsma
Electrophysiology of Gap Junctional Conductance, M. Chanson and D.C. Spray
Propagation of Pacemaker Activity: Interaction between Pacemaker Cells and Atrial Tissue, D. Noble, H.F. Brown, and R.L. Winslow
Structural Patterns of Muscle and Innervation in the Sinoatrial Node, L.A. Roberts
Pacemaker Currents and Their Neural Modulation, A. Zaza, M. Mangoni, and D. DiFrancesco
Pacemaker Activity in Explanted Cardiac Cells, O.F. Schanne, R. Dumaine, and E. Ruiz Petrich
Gastrointestinal Smooth Muscle
Pacemaker Activity and Intercellular Communication in the Gastrointestin Musculature, L.W.C. Liu, N. Sperelakis, and J.D. Huizinga
Generation and Propagation of Rhythmicity in Gastrointestinal Smooth Muscle, N.G. Publicover
Structural Aspects of Interstitial Cells of Cajal as Intestinal Pacemaker Cells, L. Thuneberg, J.J. Rumessen, H.B. Mikkelsen, S. Peters, and H. Jessen
Ion Channels Involved in Gastrointestinal Action Potential Generation., A. Molleman, S. Sims, J.C.F. Lee, and J.D. Huizinga
Spontaneous Electrical Activity and Slow-Wave Origin in the Stomach and Small Intestine, A.J. Bauer, and B. Ermentrout
??Cells of the Pancreas
Generation and Control of Bursting Electrical Activity in Pancreatic ??Cells, D.L. Cook and W.F. Hopkins
Junctional Coupling of Pancreatic ?-Cells, P. Meda
Multicellular Synchronous Calcium Oscillations in Pancreatic Islets of Langerhans, A. Nada, B. Soria, and M. Valdeolmillos
Mechanisms for Fast Intercellular Communication within a Single Islet of Langerhans, E.M Perez-Armendariz, I. Atwater, and M.V.L. Bennett
Theoretical Aspects of Synchronized Bursting in ?-Cells, A. Sherman
Pacemaker Activity and Intercellular Communication: An Introduction to the Book, J.D. Huizinga
The Heart
Generation of Pacemaker Activity in Mammalian Sinoatrial Node, W.R. Giles
The Sinoatrial Node: Structure, Inhomogeneity, and Intercellular Interaction, L.N. Bouman and H.J. Jongsma
Electrophysiology of Gap Junctional Conductance, M. Chanson and D.C. Spray
Propagation of Pacemaker Activity: Interaction between Pacemaker Cells and Atrial Tissue, D. Noble, H.F. Brown, and R.L. Winslow
Structural Patterns of Muscle and Innervation in the Sinoatrial Node, L.A. Roberts
Pacemaker Currents and Their Neural Modulation, A. Zaza, M. Mangoni, and D. DiFrancesco
Pacemaker Activity in Explanted Cardiac Cells, O.F. Schanne, R. Dumaine, and E. Ruiz Petrich
Gastrointestinal Smooth Muscle
Pacemaker Activity and Intercellular Communication in the Gastrointestin Musculature, L.W.C. Liu, N. Sperelakis, and J.D. Huizinga
Generation and Propagation of Rhythmicity in Gastrointestinal Smooth Muscle, N.G. Publicover
Structural Aspects of Interstitial Cells of Cajal as Intestinal Pacemaker Cells, L. Thuneberg, J.J. Rumessen, H.B. Mikkelsen, S. Peters, and H. Jessen
Ion Channels Involved in Gastrointestinal Action Potential Generation., A. Molleman, S. Sims, J.C.F. Lee, and J.D. Huizinga
Spontaneous Electrical Activity and Slow-Wave Origin in the Stomach and Small Intestine, A.J. Bauer, and B. Ermentrout
??Cells of the Pancreas
Generation and Control of Bursting Electrical Activity in Pancreatic ??Cells, D.L. Cook and W.F. Hopkins
Junctional Coupling of Pancreatic ?-Cells, P. Meda
Multicellular Synchronous Calcium Oscillations in Pancreatic Islets of Langerhans, A. Nada, B. Soria, and M. Valdeolmillos
Mechanisms for Fast Intercellular Communication within a Single Islet of Langerhans, E.M Perez-Armendariz, I. Atwater, and M.V.L. Bennett
Theoretical Aspects of Synchronized Bursting in ?-Cells, A. Sherman