Neurotransmitter Receptors

Part 1 General Topics: Transmitter receptors - general principles and nomenclature, F. Hucho; Historical aspects and definition. "TiPS Receptor Nomenclature Supplement 1993". Ligand binding studies - theory and experimental techniques, H. Otto; The experimental scenario; Experimental strategies; Experimental techniques; Receptor regulation, F. Nantel, M. Bouvier; Receptor regulation. Part 2 "Prototype Receptors": The nicotinic acetylcholine receptor, F. Hucho; Function and occurrence; Pharmacology and toxicology; Biochemistry; The Beta-adrenergic receptor, M. Lohse, E.J.M. Helmreich; Pharmacological characterization; Function and structure; Regulation of Beta-adrenoceptor function; Clinical aspects; Outlook. Part 3 Receptors for "Classic" neurotransmitters: GABAA and glycine receptors, A. Stephenson; GABAA and glycine receptor molecular pharmacology; GABAA and glycine receptors biochemistry and molecular biology; Oligometric receptor structures and their distribution; Functional properties of cloned GABAA and glycine receptors; GABAA and glycine receptors in disease states; Muscarinic acetylcholine receptors, J. Jaerv, A. Rinken; Phenomena used for receptor assay; Compounds interacting with the receptor; Pharmacological and molecular subtypes of muscarinic receptor; Receptor molecule; Ligand-receptor interactions; Mechanisms of signal transduction; Two-site receptor model; Receptors for 5-hydroxytryptamine, D.H. Bobker, J.T. Williams; History; Nomenclature; Biochemistry of 5-HT synthesis, storage and neurotransmission; Anatomy of central serotonin; 5-HT1A receptor; 5-HT1B and 5-HT1D receptors; 5-HT1C receptor; 5-HT2 receptors; 5-HT3 receptor; 5-HT receptors that stimulate adenylate cyclase; Molecular biology; Dopamine receptors, P.G. Strange; Functions and distribution of dopamine receptors; Dopamine receptor subtypes - definitions and overall properties; Biochemical characterization of dopamine receptors; Glutamate receptors, G.E. Fagg, A.C. Foster; Function and occurrence; Pharmacology and toxicology; Molecular biology; Miscellaneous effects; Opioid receptors, E.A. Barnard, J. Simon; Multiple opioid receptors and their ligands; Subtypes of opioid receptor types; Cellular mechanisms of opioid actions; The states of opioid receptors in the membrane; Solubilization and purification of opioid receptors; Molecular biology of opioid receptors; Guanylyl cyclases as effectors of hormone and neurotransmitter receptor, D. Koesling, E. Boehme, G. Schultz. (Part contents).