Practical Genetics for the Ob-Gyn
Published on 16. August 2014
Book
Paperback/Softback
192 pages
978-0-07-179721-4 (ISBN)
Description
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.
Understand the clinical application of genetics in ob-gyn practice with this case-based text This up-to-date resource surveys the modern field of genetics and provides you with a practical understanding of its clinical uses.
Whether determining who is pre-disposed to disease, howa patient will respond to therapy, or what the optimal cancer treatment might be based on tumor profiles, this is the only guide to help efficiently interpret and utilize genetic data across the full spectrum of ob-gyn clinical scenarios.
Practical Genetics for the Ob-Gyn is organized around three central themes: basic genetic principles, clinical applications of ob-gyn practice, and common methods of genetic testing. Opening each chapter is a patient case study that establishes a realistic clinicalcontext for the subsequent genetics-based material addressed.
Understand the clinical application of genetics in ob-gyn practice with this case-based text This up-to-date resource surveys the modern field of genetics and provides you with a practical understanding of its clinical uses.
Whether determining who is pre-disposed to disease, howa patient will respond to therapy, or what the optimal cancer treatment might be based on tumor profiles, this is the only guide to help efficiently interpret and utilize genetic data across the full spectrum of ob-gyn clinical scenarios.
Practical Genetics for the Ob-Gyn is organized around three central themes: basic genetic principles, clinical applications of ob-gyn practice, and common methods of genetic testing. Opening each chapter is a patient case study that establishes a realistic clinicalcontext for the subsequent genetics-based material addressed.
More details
Language
English
Place of publication
United States
Publishing group
McGraw-Hill Education - Europe
Target group
Professional and scholarly
Product notice
Paperback (trade)
Unsewn / adhesive bound
Illustrations
50 Illustrations
Dimensions
Height: 233 mm
Width: 154 mm
Thickness: 12 mm
Weight
315 gr
ISBN-13
978-0-07-179721-4 (9780071797214)
Schweitzer Classification
Other editions
Additional editions
W. Allen Hogge | Aleksandar Rajkovic
Practical Genetics for the Ob-Gyn
E-Book
11/2014
1st Edition
McGraw-Hill Education
€149.69
Available for download
Persons
W. Allen Hogge, MD, is the Professor and Chair of the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of Pittsburgh Schools of Health Sciences, Pittsburgh, Pennsylvania.
Aleksandar Rajkovic, MD, PhD, is Associate Professor, Department of Obstetrics, Gynecology, and Reproductive Science; and Chief, Division of Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Aleksandar Rajkovic, MD, PhD, is Associate Professor, Department of Obstetrics, Gynecology, and Reproductive Science; and Chief, Division of Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Content
I. Basic Genetic Principles
1. Gene Structure and Function
2. Chromosome Structure and Function
3. Patterns of Inheritance
a. Mendelian inhereditance (Include clinical examples for each)
i. Autosomal dominant
ii. Autosomal recessive
iii. Co-dominant
iv. X-linked
b. Non-mendelian inhereditance (include clinical examples)
i. Hereditary unstable DNA
ii. Imprinting
iii. Uniparental disomy
iv. Mitochondrial inhereditance
v. Germ line mosaicism
c. Multifactorial and Polygenic Inhereditance
4. Chromosomal Abnormalities
a. Aneuploidy
b. Deletion, Duplication, and Inversions
II. Clinical Genetics in the Context of Obstetrics and Gynecology
5. Taking a family history
6. Principles of genetic counseling
7. Preconception counseling
8. Screening for genetic disorders in pregnancy
9. Methods of prenatal diagnosis
10. Common fetal malformations diagnosed by ultrasound
11. Gynecologic disorders with a genetic causation
12. Hereditary cancer syndromes
13. Disorders of sexual differentiation
14. Infertility and pregnancy loss
III. Methods of Genetic Testing
15. Traditional cytogenetic testing
16. Molecular cytogenetic testing
a. Fluorescent in-situ hybridization
b. Microarrays
17. Molecular diagnostic testing
a. Southern blot analysis
b. Polymerase chain reaction
c. DNA sequencing
d. New approaches to diagnostic testing
1. Gene Structure and Function
2. Chromosome Structure and Function
3. Patterns of Inheritance
a. Mendelian inhereditance (Include clinical examples for each)
i. Autosomal dominant
ii. Autosomal recessive
iii. Co-dominant
iv. X-linked
b. Non-mendelian inhereditance (include clinical examples)
i. Hereditary unstable DNA
ii. Imprinting
iii. Uniparental disomy
iv. Mitochondrial inhereditance
v. Germ line mosaicism
c. Multifactorial and Polygenic Inhereditance
4. Chromosomal Abnormalities
a. Aneuploidy
b. Deletion, Duplication, and Inversions
II. Clinical Genetics in the Context of Obstetrics and Gynecology
5. Taking a family history
6. Principles of genetic counseling
7. Preconception counseling
8. Screening for genetic disorders in pregnancy
9. Methods of prenatal diagnosis
10. Common fetal malformations diagnosed by ultrasound
11. Gynecologic disorders with a genetic causation
12. Hereditary cancer syndromes
13. Disorders of sexual differentiation
14. Infertility and pregnancy loss
III. Methods of Genetic Testing
15. Traditional cytogenetic testing
16. Molecular cytogenetic testing
a. Fluorescent in-situ hybridization
b. Microarrays
17. Molecular diagnostic testing
a. Southern blot analysis
b. Polymerase chain reaction
c. DNA sequencing
d. New approaches to diagnostic testing