Intracellular Signal Transduction: Volume 36
Intracellular Signal Transduction
Published on 30. August 1996
Book
Paperback/Softback
310 pages
978-0-12-513805-5 (ISBN)
Description
Signal transduction is one of the most rapidly expanding fields in biomedical research. Written by renowned experts, Intracellular Signal Transduction provides up-to-date reviews on the role of protein phosphorylation cascades, and the structure, regulation, and function of protein kinases and phosphatases. This volume was compiled in honor of Dr. Edwin Krebs' pioneering work in the field of signal transduction which earned him a Nobel Prize. It provides information in a variety of areas relating to the biochemistry, cell biology, and pharmacology of the signal transduction process in eukaryotic cells.
Reviews / Votes
Praise for the Serial"Recommended not only to pharmacologists but also to all those in related disciplines."
--NATURE
"Superb reading material."
--JOURNAL OF PHARMACEUTICAL SCIENCES
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
--H.E. Kaufmann in CHEMOTHERAPY
More details
Series
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
College/higher education
Professional and scholarly
Dimensions
Height: 229 mm
Width: 152 mm
Weight
480 gr
ISBN-13
978-0-12-513805-5 (9780125138055)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Persons
Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children. Joseph T. Coyle, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA Angus C. Nairn is currently Associate Professor at The Rockefeller University. He has published a large number of papers concerned with the structure and regulation of protein kinases and phosphatases involved in signal transduction, particularly with respect to signalling by calcium.
Content
M. Montminy, P. Brindle, J. Arias, K. Ferreri, and R. Armstrong, Regulation of Somatostatin Gene Transcription by cAMP.
P. Cohen, Dissection of Protein Kinase Cascades That Mediate Cellular Response to Cytokines and Cellular Stress.
F. Burns, A.Z. Zhao, and J.A. Beavo, Cyclic Nucleotide Phosphodiesterases: Gene Complexity, Regulation by Phosphorylation and Physiological Implications.
M.H. Cobb, S. Xu, M. Cheng, D. Ebert, D. Robbins, E. Goldsmith, and M. Robinson, Structural Analysis of the MAP Kinase ERK2 and Studies of MAP Kinase Regulatory Pathways.
P.T.W. Cohen, M.X. Chen, and C.G. Armstrong, Novel Protein Phosphatases which may Participate in Cell Signalling.
N.K. Tonks, Protein Tyrosine Phosphatases and the Control of Cellular Signaling Responses.
T. Moriguchi, Y. Gotoh, and E. Nishida,
Roles of the MAP Kinase Cascade in Vertebrate.
T. Takenawa, K. Miura, H. Miki, and K. Watanabe, Signal Transductions of SH2/SH3: ASH/GRB-2 Downstream Signalings.
S.-I. Hakomori, Sphingolipid-Dependent Protein Kinases.
T. Haga, K. Haga, K. Kameyama, and H. Tsuga, G-Protein-Coupled Receptor Kinase: Phosphorylation of Muscarinic Receptors and Facilitation of Receptor Sequestration.
H. Hidaka and H. Yokokura, Molecular and Cellular Pharmacology of A Calcium/Calmodulin-Dependent Protein Kinase II (CaM Kinase II) Inhibitor, KN-62, and Proposal of
CaM Kinase Phosphorylation Cascades.
B.E. Kemp, J.A. Barden, B. Kobe, C. House, and M.W. Parker, Intrasteric Regulation of Calmodulin-Dependent Protein Kinases.
M.R. Picciotto, K.L. Nastiuk, and A.C. Nairn, Structure, Regulation and Function of Calcium/Calmodulin-Dependent Protein Kinase I.
M. Hagiwara, A. Shimomura, K. Yoshida, and J. Imaki, Gene Expression and CREB Phosphorylation Induced by cAMP and Ca2+ in Neuronal Cells.
Chapter References.
Subject Index.
P. Cohen, Dissection of Protein Kinase Cascades That Mediate Cellular Response to Cytokines and Cellular Stress.
F. Burns, A.Z. Zhao, and J.A. Beavo, Cyclic Nucleotide Phosphodiesterases: Gene Complexity, Regulation by Phosphorylation and Physiological Implications.
M.H. Cobb, S. Xu, M. Cheng, D. Ebert, D. Robbins, E. Goldsmith, and M. Robinson, Structural Analysis of the MAP Kinase ERK2 and Studies of MAP Kinase Regulatory Pathways.
P.T.W. Cohen, M.X. Chen, and C.G. Armstrong, Novel Protein Phosphatases which may Participate in Cell Signalling.
N.K. Tonks, Protein Tyrosine Phosphatases and the Control of Cellular Signaling Responses.
T. Moriguchi, Y. Gotoh, and E. Nishida,
Roles of the MAP Kinase Cascade in Vertebrate.
T. Takenawa, K. Miura, H. Miki, and K. Watanabe, Signal Transductions of SH2/SH3: ASH/GRB-2 Downstream Signalings.
S.-I. Hakomori, Sphingolipid-Dependent Protein Kinases.
T. Haga, K. Haga, K. Kameyama, and H. Tsuga, G-Protein-Coupled Receptor Kinase: Phosphorylation of Muscarinic Receptors and Facilitation of Receptor Sequestration.
H. Hidaka and H. Yokokura, Molecular and Cellular Pharmacology of A Calcium/Calmodulin-Dependent Protein Kinase II (CaM Kinase II) Inhibitor, KN-62, and Proposal of
CaM Kinase Phosphorylation Cascades.
B.E. Kemp, J.A. Barden, B. Kobe, C. House, and M.W. Parker, Intrasteric Regulation of Calmodulin-Dependent Protein Kinases.
M.R. Picciotto, K.L. Nastiuk, and A.C. Nairn, Structure, Regulation and Function of Calcium/Calmodulin-Dependent Protein Kinase I.
M. Hagiwara, A. Shimomura, K. Yoshida, and J. Imaki, Gene Expression and CREB Phosphorylation Induced by cAMP and Ca2+ in Neuronal Cells.
Chapter References.
Subject Index.