Conceptual Breakthroughs in Comparative Animal Physiology
Will be published approx. on 1. October 2026
Book
Paperback/Softback
276 pages
978-0-12-817366-4 (ISBN)
Description
Conceptual Breakthroughs in Comparative Animal Physiology tells a story of innate human curiosity about the natural world, and a deeply creative discipline, shaped by varied environments, unusual organisms, elegant experiments, and the persistent effort to understand how animals work and why they work the way they do-along the way discovering "adaptations and mechanisms of the most surprising character".
Written by two leading experts in the field, each chapter reflects on the origins of ideas and the approach of turning natural diversity into experimental design. From deserts to oceans, from the anoxia-tolerant animals to endothermic insects, from deep-diving mammals to the integration of "omics," each chapter follows the discoveries and people who were compelled to modify their view of "what life can do." The chapters also highlight the long-term influence of key conceptual breakthroughs, demonstrating how insights from comparative physiology have shaped not only the field itself but also, ecology, evolution, and engineering.
As scientists strive to understand the complexity of living systems, the book underscores the inherent integrative nature of comparative physiology, revealing a process that strives to connect genes to organisms and organisms to environments, and providing a framework for understanding the diversity of life. This is an essential resource for undergraduates, graduate students and researchers interested in physiology with its comprehensive synopsis on the field's foundational history and significant advances.
Written by two leading experts in the field, each chapter reflects on the origins of ideas and the approach of turning natural diversity into experimental design. From deserts to oceans, from the anoxia-tolerant animals to endothermic insects, from deep-diving mammals to the integration of "omics," each chapter follows the discoveries and people who were compelled to modify their view of "what life can do." The chapters also highlight the long-term influence of key conceptual breakthroughs, demonstrating how insights from comparative physiology have shaped not only the field itself but also, ecology, evolution, and engineering.
As scientists strive to understand the complexity of living systems, the book underscores the inherent integrative nature of comparative physiology, revealing a process that strives to connect genes to organisms and organisms to environments, and providing a framework for understanding the diversity of life. This is an essential resource for undergraduates, graduate students and researchers interested in physiology with its comprehensive synopsis on the field's foundational history and significant advances.
More details
Series
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Advanced graduate and undergraduate students, researchers, and specialists in evolutionary biology and evolutionary studies
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 229 mm
Width: 152 mm
Weight
450 gr
ISBN-13
978-0-12-817366-4 (9780128173664)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Dr. James Hicks currently serves as a Professor in the Department of Ecology and Evolutionary Biology at University of California Irvine. He received his M.S. in Biology and later his Ph.D. in Biomedical Sciences from the University of New Mexico in Albuquerque. Dr Hicks is a member of the American Physiological Society, the Society for Integrative and Comparative Biology, and the Society for Experimental Biology. He has authored and contributed to numerous publications on animal physiology and ecology. Internationally, he is currently a member of the Science and Technology Advisory Committee for the University of Aarhus in Denmark. Dr. Tobias Wang is a professor of Zoophysiology at Aarhus University. He is interested in how animals function and how they have adapted to the environments where they live. Being trained as a biologist, he takes an evolutionary approach to understand the evolution of physiological systems amongst vertebrates, and collaborate widely with medical physiologist and molecular biologists in my studies on heart function in various animals.
Content
1. 1878: Claude Bernard and "la fixite du milieu interieur"
2. 1910 -1961: From Reflexes to Rhythms: The Discovery of Central Pattern Generators
3. 1914 -1948: The Concept of Critical Oxygen Tension (PcritO2) and the limits of aerobic metabolism
4. 1929: Homeostasis and the "Wisdom of the Body"
5. 1929: The Progress of Physiology: August Krogh at the 1929 Congress
6. 1930 - 1935 Physiology of the Estivating Lungfish: Ecological and Evolutionary Insights
7. 1930- 1938: The Foundations of Osmoregulation in Aquatic Vertebrates: Early Discoveries in Teleost Fish and Elasmobranchs
8. 1931 - 1963: The History of Oxygen Secretion in the Fish Swim Bladder
9. 1932: From Mouse to Elephant: How Kleiber Transformed Our Understanding of Metabolism
10. 1933: James Gray and the Foundations of Animal Movement
11. 1935-1949: Krogh and Ussing: The Early Use of Isotopes in Biology
12. 1936-1961: Cryoprotectants in Comparative Physiology: Convergent Strategies for Life Below Zero
13. 1939-1942: The Master Switch of Life
14. 1940-1963: Pioneers of Desert Physiology: The Early Comparative Studies of Water Economy in Mammals
15. 1941: Myogenic Endothermy in Insects: The mechanism of flight preparation
16. 1944 The Desert Laboratory: Discovering Reptile Thermoregulation in the Coachella Valley
17. 1944 - 1950: Breathing in Bursts: Discontinuous gas exchange in insects
18. 1947: The Fry Paradigm: A Framework for Animal Activity
19. 1948: Hibernation: connection between metabolism and body temperature
20. 1949: Beyond One Spike, One Twitch: The Discovery of Asynchronous Muscle
21. 1950: Coulson and Hernandez and the Alkaline Tide: Acid-Base Physiology in Postprandial Vertebrates
22. 1950: Thermal Adaptations in Arctic and Tropical Mammals and Birds
23. 1954: Oxygen Without Red Blood Cells, Life Without Freezing: The Polar Fish Experiment
24. 1955-1957: Irving, Scholander and the Arctic Lesson: How Vessels Conserve Heat
25. 1955-1975: The doubly labeled water technique: measuring field energetics
26. 1958: Beyond the Kidney: The Salt Glands of Marine Birds and Reptiles
27. 1963: Homeostasis in the Field: The Water Economy of Birds
28. 1963: Ignition Point: How Arousal from Hibernation Unveiled a Thermogenic Organ
29. 1963-1993: The Big Four in Comparative Locomotion, Inverted pendulums, running springs, elastic energy storage and dynamic similarity
30. 1966-67: The Role of the Hypothalamus in Thermoregulation: Contributions from Comparative Physiology
31. 1966: Low PaCO?: The Signature Physiology of Water Breathers
32. 1966: How Regional and Facultative Endothermy Transformed the Study of Ectothermic Physiology
33. 1966: Cardiac Shunts: Mechanisms and Functional Significance
34. 1966-1972: Cooling the Brain: Countercurrent Exchange and the Carotid Rete
35. 1966: From Whalers' Lines to Time-Depth Recorders: Tracing the Limits of Marine Mammal Diving
36. 1968-1972: Anaerobic Scope and Anaerobic Capacity in Ectotherms
37. 1968- 1974: The Mystery of Exercise Hyperpnea and the Role of Intrapulmonary Chemoreceptors
38. 1966-1968: Life Without Oxygen: Metabolic Depression and the Anoxic Turtle
39. 1970-1975: Comparative Respiratory Physiology and the Goettingen Models
40. 1972: Fish Gills Under Competing Demands: Oxygen Uptake vs. Ionic Balance
41. 1970-1972: The Cost of Transport: A Unifying Measure for Animal Locomotion
42. 1972: The Buffalo Curve and The Alpha-stat Hypothesis
43. 1971-72: Avian Gas Exchange: Countercurrent vs. Crosscurrent Mechanisms in Bird Lungs
44. 1973: Torkel Weis-Fogh: Discovering the Clap-and-Fling Mechanism
45. 1973-2002: Biochemical Adaptation: A Serendipitous Collaboration that Shaped a Discipline
46. 1974-1985: Keeping Membranes Fluid: The Discovery of Homeoviscous Adaptations to Temperature and Pressure
47. 1975: Behavioral Fever and Survival- the Logic of Fever
48. 1977-1983: The Worms that Changed our View of Life: Chemoautotrophy at Hydrothermal Vents
49. 1979: Maximum Metabolic Rate and the Making of Endotherms: The Aerobic Capacity Hypothesis
50. 1980: Breath-Hold Boundaries: Defining the Aerobic Dive Limit
51. 1980: "Drunken" Goldfish: ETOH production during anoxia
52. 1981-1994: The Rediscovery of Safety Factors as a Principle of Form and Function
53. 1981: Strong Ion Difference: Rethinking Acid-Base Balance Beyond Bicarbonate
54. 1981: Symmorphosis: Economy of Design in the Oxygen Transport Cascade
55. 1982: Norbert Heisler: preferential regulation of intracellular pH
56. 1982: Discovering Adrenergic Control of Red Blood Cells: The Na?/H? Exchange Mechanism
57. 1985: Turning Down the Heat: Comparative Patterns of Hypoxia-Induced Anapyrexia
58. 1985: A New Way to See Muscle Work: Josephson's Work-Loop Insight
59. 1986: Cold Limits, Oxygen Limits: Channel Arrest as a Unifying Strategy
60. 1987: Charting a New Course: "New Directions in Ecological Physiology"
61. 1987: Solvent Drag and Sugar Flow: The Paracellular Pathway for Glucose
62. 2000: The Rediscovery of Evolutionary Physiology
63. 1990: Why Animals Don't Burn Out: The Hidden Boundaries of Sustained Metabolism
64. 1985-1994: Beyond Just-So Stories: Phylogenies and the Comparative Method
65. 1994-1998: The Dynamic Cost of Eating: Specific Dynamic Action and the Rise of the "Dynamic Gut" in Comparative Physiology
66. 1997-2003: Beyond Plasticity: The Dynamics of Phenotypic Flexibility
67. 2001: Gene Expression Profiling in Non-model Organisms: The Introduction of 'omics' to Comparative Physiology
68. 2001-2008: Limits to Life and The Ongoing Debate on Oxygen, Temperature, and Tolerance
69. 2006: From Physiological Ecology to Conservation Physiology: Mechanisms with a Mission
70. 2010: Beyond Birds: Unidirectional Airflow in the Reptilian Lung
2. 1910 -1961: From Reflexes to Rhythms: The Discovery of Central Pattern Generators
3. 1914 -1948: The Concept of Critical Oxygen Tension (PcritO2) and the limits of aerobic metabolism
4. 1929: Homeostasis and the "Wisdom of the Body"
5. 1929: The Progress of Physiology: August Krogh at the 1929 Congress
6. 1930 - 1935 Physiology of the Estivating Lungfish: Ecological and Evolutionary Insights
7. 1930- 1938: The Foundations of Osmoregulation in Aquatic Vertebrates: Early Discoveries in Teleost Fish and Elasmobranchs
8. 1931 - 1963: The History of Oxygen Secretion in the Fish Swim Bladder
9. 1932: From Mouse to Elephant: How Kleiber Transformed Our Understanding of Metabolism
10. 1933: James Gray and the Foundations of Animal Movement
11. 1935-1949: Krogh and Ussing: The Early Use of Isotopes in Biology
12. 1936-1961: Cryoprotectants in Comparative Physiology: Convergent Strategies for Life Below Zero
13. 1939-1942: The Master Switch of Life
14. 1940-1963: Pioneers of Desert Physiology: The Early Comparative Studies of Water Economy in Mammals
15. 1941: Myogenic Endothermy in Insects: The mechanism of flight preparation
16. 1944 The Desert Laboratory: Discovering Reptile Thermoregulation in the Coachella Valley
17. 1944 - 1950: Breathing in Bursts: Discontinuous gas exchange in insects
18. 1947: The Fry Paradigm: A Framework for Animal Activity
19. 1948: Hibernation: connection between metabolism and body temperature
20. 1949: Beyond One Spike, One Twitch: The Discovery of Asynchronous Muscle
21. 1950: Coulson and Hernandez and the Alkaline Tide: Acid-Base Physiology in Postprandial Vertebrates
22. 1950: Thermal Adaptations in Arctic and Tropical Mammals and Birds
23. 1954: Oxygen Without Red Blood Cells, Life Without Freezing: The Polar Fish Experiment
24. 1955-1957: Irving, Scholander and the Arctic Lesson: How Vessels Conserve Heat
25. 1955-1975: The doubly labeled water technique: measuring field energetics
26. 1958: Beyond the Kidney: The Salt Glands of Marine Birds and Reptiles
27. 1963: Homeostasis in the Field: The Water Economy of Birds
28. 1963: Ignition Point: How Arousal from Hibernation Unveiled a Thermogenic Organ
29. 1963-1993: The Big Four in Comparative Locomotion, Inverted pendulums, running springs, elastic energy storage and dynamic similarity
30. 1966-67: The Role of the Hypothalamus in Thermoregulation: Contributions from Comparative Physiology
31. 1966: Low PaCO?: The Signature Physiology of Water Breathers
32. 1966: How Regional and Facultative Endothermy Transformed the Study of Ectothermic Physiology
33. 1966: Cardiac Shunts: Mechanisms and Functional Significance
34. 1966-1972: Cooling the Brain: Countercurrent Exchange and the Carotid Rete
35. 1966: From Whalers' Lines to Time-Depth Recorders: Tracing the Limits of Marine Mammal Diving
36. 1968-1972: Anaerobic Scope and Anaerobic Capacity in Ectotherms
37. 1968- 1974: The Mystery of Exercise Hyperpnea and the Role of Intrapulmonary Chemoreceptors
38. 1966-1968: Life Without Oxygen: Metabolic Depression and the Anoxic Turtle
39. 1970-1975: Comparative Respiratory Physiology and the Goettingen Models
40. 1972: Fish Gills Under Competing Demands: Oxygen Uptake vs. Ionic Balance
41. 1970-1972: The Cost of Transport: A Unifying Measure for Animal Locomotion
42. 1972: The Buffalo Curve and The Alpha-stat Hypothesis
43. 1971-72: Avian Gas Exchange: Countercurrent vs. Crosscurrent Mechanisms in Bird Lungs
44. 1973: Torkel Weis-Fogh: Discovering the Clap-and-Fling Mechanism
45. 1973-2002: Biochemical Adaptation: A Serendipitous Collaboration that Shaped a Discipline
46. 1974-1985: Keeping Membranes Fluid: The Discovery of Homeoviscous Adaptations to Temperature and Pressure
47. 1975: Behavioral Fever and Survival- the Logic of Fever
48. 1977-1983: The Worms that Changed our View of Life: Chemoautotrophy at Hydrothermal Vents
49. 1979: Maximum Metabolic Rate and the Making of Endotherms: The Aerobic Capacity Hypothesis
50. 1980: Breath-Hold Boundaries: Defining the Aerobic Dive Limit
51. 1980: "Drunken" Goldfish: ETOH production during anoxia
52. 1981-1994: The Rediscovery of Safety Factors as a Principle of Form and Function
53. 1981: Strong Ion Difference: Rethinking Acid-Base Balance Beyond Bicarbonate
54. 1981: Symmorphosis: Economy of Design in the Oxygen Transport Cascade
55. 1982: Norbert Heisler: preferential regulation of intracellular pH
56. 1982: Discovering Adrenergic Control of Red Blood Cells: The Na?/H? Exchange Mechanism
57. 1985: Turning Down the Heat: Comparative Patterns of Hypoxia-Induced Anapyrexia
58. 1985: A New Way to See Muscle Work: Josephson's Work-Loop Insight
59. 1986: Cold Limits, Oxygen Limits: Channel Arrest as a Unifying Strategy
60. 1987: Charting a New Course: "New Directions in Ecological Physiology"
61. 1987: Solvent Drag and Sugar Flow: The Paracellular Pathway for Glucose
62. 2000: The Rediscovery of Evolutionary Physiology
63. 1990: Why Animals Don't Burn Out: The Hidden Boundaries of Sustained Metabolism
64. 1985-1994: Beyond Just-So Stories: Phylogenies and the Comparative Method
65. 1994-1998: The Dynamic Cost of Eating: Specific Dynamic Action and the Rise of the "Dynamic Gut" in Comparative Physiology
66. 1997-2003: Beyond Plasticity: The Dynamics of Phenotypic Flexibility
67. 2001: Gene Expression Profiling in Non-model Organisms: The Introduction of 'omics' to Comparative Physiology
68. 2001-2008: Limits to Life and The Ongoing Debate on Oxygen, Temperature, and Tolerance
69. 2006: From Physiological Ecology to Conservation Physiology: Mechanisms with a Mission
70. 2010: Beyond Birds: Unidirectional Airflow in the Reptilian Lung