Molecular Chaperones and Cell Signalling

Preface; Part I. Molecular Chaperones and the Cell Stress Response: 1. Chaperone function: the orthodox view R. J. Ellis; 2. Intracellular disposition of mitochondrial molecular chaperones: Hsp60, mHsp70, Cpn10 and TRAP-1 R. S. Gupta, T. Bowes, S. Sadacharan and B. Singh; Part II. Changing Paradigms of Protein Trafficking and Protein Function: 3. Novel pathways of protein secretion G. Chimini and A. Rubartelli; 4. Moonlighting proteins: proteins with more than one function C. J. Jeffery; 5. Molecular chaperones: the unorthodox view B. Henderson and A. Shamaei-Tousi; Part III. Molecular Chaperones as Cell Regulators: 6. Cell-cell signalling properties of chaperonins A. R. M. Coates; 7. Toll-like receptor-dependent activation of antigen presenting cells by Hsp60, Hsp70 and Gp96 R. M. Vabulas and H. Wagner; 8. Regulation of signal transduction by intracellular and extracellular Hsp70 A. Asea and S. Calderwood; 9. Hsp72 and cell signalling M. Y. Sherman; 10. Heat shock proteins, their cell surface receptors and effect on the immune system T. Lehner, Y. Wang, T. Whittall and L. A. Bergmei; 11. Molecular chaperone-Cytokine interactions at the transcriptional level A. Stephanou and D. S. Latchman; Part IV. Physiological and Pathophysiological Signals: 12. Heat shock protein release and naturally-occurring exogenous heat shock proteins J. Frostegard and A. G. Pockley; 13. Hsp27 as an anti-inflammatory Protein K. Laudanski, A. De and C. Miller-Graziano; 14. Bip, a negative immune regulator involved in rheumatoid arthritis V. M. Corrigal and G. S. Panayi; Part V. Molecular Chaperones as Therapeutics: 15. Neuroendocrine aspects of the molecular chaperones ADNF and ADNP I. Gozes, I. Vulih, I. Spivak-Pohis and S. Furman; 16. Heat shock proteins regulate by both molecular and network cross-reactivity F. J. Quintana and I. R. Cohen; 17. Heat shock protein fusions: a platform for the induction of antigen-specific immunity L. Mizzen and J. Neefe; 18. Molecular chaperones as inducers of tumour immunity P. P. Bannerjee and Z. Li; Part VI. What Does the Future Hold?: 19. Gazing into the crystal ball: the unfolding future of molecular chaperones L. Hightower.