Signal Transduction
Published on 31. October 1996
Book
Paperback/Softback
384 pages
978-0-412-70810-7 (ISBN)
Description
This volume gives an up-to-date summary of the information available about signal transduction, each chapter summarizing what is known about a particular aspect of the subject, and emphasizing central themes and issues. Part one covers the structural and functional properties of the major classes of cell surface receptors; part two focuses on components important for cytoplasmic signal transduction; and part three deals with nuclear responses.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Oxford University Press
Target group
College/higher education
Professional and scholarly
Illustrations
35 illustrations, index
Dimensions
Height: 244 mm
Width: 188 mm
Weight
560 gr
ISBN-13
978-0-412-70810-7 (9780412708107)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Part One: Cell surface receptors. Signalling through receptor tyrosine kinases. Signalling through cytokine class I receptors. Signalling through cytokine class II receptors. Signalling through hemopoietic antigen receptors. Signalling through protein serine/threonine kinase receptors. Signalling through members of the tumor necrosis factor receptor superfamily. Signalling through G-protein coupled receptors. Receptor-mediated endocytosis of growth factors. Part Two: Cytoplasmic signal transmission. SH2,SH3 and PH domains. Ras signalling pathway. MAP kinases in multiple signaling pathways. Function of phospholipases in signal tranduction. Multiple roles for phosphoinositide 3-kinases in signal transduction. Calcium signalling. Cyclic AMP and cyclic GMP in cell signalling. The protein kinase C gene family. Protein tyrosine phosphatases. Protein serine/threonine phosphatases. G proteins in signal transduction. Part Three: Nuclear Responses. Steroid hormone and nuclear receptors. Transcription factors. The p53 tumor suppressor. Cell cyle regulation.