Bioorganic Chemistry
Nucleic Acids
Published on 11. July 1996
Book
Hardback
512 pages
978-0-19-508467-2 (ISBN)
Description
This work provides an overview of DNA and RNA including coverage of biosynthesis, stucture, and their functions in information storage and transmission. A review of fundamental material is presented in the first half of each chapter followed by a fairly detailed research example selected by the chapter author from current research.
Reviews / Votes
"It is an excellent starting point for any chemist seeking to familiarize him- or herself with current topics related to the chemistry, enzymology, molecular recognition, and structure of nucleic acids....This book succeeds in presenting a clear, yet suitabley advanced view of modern nucleic acid chemistry and thus will prove very useful to educators, students, and established researchers who are interested in this field." -- Journal of the AmericanChemical Society
"...the editor and his contribuators have succeeded admirably in producing a modestly priced book that will be very useful, not only for its target audience of students but for anyone wishing to have a concise yet thorough overview of the field."--Manfred E. Wolff, Journal of Medicinal Chemistry
More details
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Illustrations
halftones, numerous line figures, tables
Dimensions
Height: 242 mm
Width: 171 mm
Thickness: 28 mm
Weight
914 gr
ISBN-13
978-0-19-508467-2 (9780195084672)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Content
1. Fundamentals of Nucleic Acids ; 2. Chemical Synthesis of DNA/RNA ; 3. Enzymatic Methods for Preparation and Manipulation of Nucleic Acids ; 4. Structure of DNA and RNAM. ; 5. Chemical Mapping of Nucleic Acid Conformation ; 6. Introduction to 1H NMR Spectroscopy of DNA ; 7. The Formation of Alternative Structures in DNA ; 8. Reporter Groups for the Analysis of Nucleic Acid Structure ; 9. Nucleic Acid Binding and Catalysis by Metal Ions ; 10. Small Molecule-DNA Interaction ; 11. The Chemistry of Protein-DNA Interactions ; 12. Antisense/Antigene Oligonucleotides ; 13. Catalytic RNA ; 14. The Polymerase Chain Reaction and In Vitro Random Selection