
Cardiovascular Biomaterials
Garth W. Hastings(Editor)
Springer (Publisher)
Published on 16. December 1991
Book
Hardback
XIV, 198 pages
978-3-540-19666-2 (ISBN)
Description
Cardiovascular Biomaterials presents current research material developed by contributors from universities and professional laboratories in the UK, USA, Canada, and Germany.
More details
Edition
1st Edition.
Language
English
Place of publication
London
United Kingdom
Publishing group
Springer Berlin
Target group
College/higher education
Professional and scholarly
Research
Illustrations
77 s/w Abbildungen
biography
Dimensions
Height: 24.2 cm
Width: 17 cm
Weight
625 gr
ISBN-13
978-3-540-19666-2 (9783540196662)
DOI
10.1007/978-1-4471-1847-3
Schweitzer Classification
Other editions
Additional editions

Content
1 Mechanical Properties of Arteries and Arterial Grafts.- Mechanical Properties of Arteries.- Structure of the Arterial Wall.- Wall Distensibility In Vivo.- Elastic Properties.- Viscoelastic Properties.- Effect of Age and Disease on Arterial Elasticity.- PET and PTFE Prostheses.- PET and PTFE Fabric Prostheses.- Expanded PTFE Prostheses.- Mechanical Properties of PET and PTFE Prostheses...- Compliance.- Long-Term Properties.- Biological Grafts.- Human Umbilical Vein Grafts.- Autogenous Vein Grafts.- Elastomeric Prostheses.- Conclusions.- 2 Blood Compatibility in Cardiopulmonary Bypass.- Blood-Material Interactions.- Haemostasis and Thrombosis.- Natural and Artificial Surfaces.- Consequences of Blood Contact With Artificial Surfaces.- Role of Antithrombotic Agents.- Blood Gas Exchange in Extracorporeal Devices.- Gas Exchange.- Blood Flow.- Device Utilization.- Influence of Cardiopulmonary Bypass on Blood Components.- Nature of Process.- Circuit Priming.- Microemboli.- Alteration to Blood Components.- 3 Collagen in Cardiovascular Tissues.- Collagen in Health and Disease.- The Collagen Molecule.- Biosynthesis.- The Procollagen Molecule.- Intracellular Event Leading to the Synthesis of Procollagen.- Translational, Co-translational and Early Post-translational Events.- Intracellular Translocation of Procollagen and Extrusion into the Extracellular Space.- Lysyl Oxidase.- Fibrillogenesis.- Collagen Metabolism.- Different Types of Collagen.- Type I Collagen.- Type III Collagen.- Type IV Collagen and Other Basement Membrane-Associated Macromolecules.- Type V Collagen.- Non-collagenous Proteins Associated with Basement Membranes.- Laminin.- Fibronectin.- Proteoglycans.- Continuum Between Cytoplasm and Extracellular Matrix...- Wound Healing.- Fibrosis.- Fibrotic Response to Implantation of Foreign Materials...- Collagen Degradation.- Crosslinking.- Intramolecular and Intermolecular Cross-links.- Collagen Composition of the Normal and Diseased Blood Vessel Wall.- Blood Vessels: Arteries and Veins.- Heart Valves.- Biomechanical Modulation of Connective Tissue Metabolism.- Collagen, Platelet Aggregation and Thrombosis.- Collagen as a Biomaterial.- Crosslinking of Collagen by Glutaraldehyde.- Vascular Grafts.- Relationship Between Surface Charge of the Vascular Interface and Thrombosis.- Calcification of Vascular Tissues.- Mechanisms of Calcification.- Calcification of Collagen-Based Cardiovascular Prostheses.- 4 Biostability of Vascular Protheses.- Current Vascular Prostheses.- Unprocessed Biological Prostheses.- Processed Biological Prostheses.- The Synthetic or Alloplastic Prostheses.- Biological Response.- Biological Grafts.- PET Vascular Prostheses.- PTFE Vascular Prostheses.- Long-Term Failure Modes.- Processed Biological Prostheses.- PTFE.- PET Vascular Prostheses.- New Materials.- Processed Biological Prostheses.- New Synthetic Grafts.- Conclusion.- 5 Heart Valve Replacements: Problems and Developments.- Mechanical Valves.- Tissue Valves.- Conclusions.- 6 Cardiac Assist Devices.- Housing.- Diaphragm.- Valves.- Conduits.- Comphance Chamber.