
Handbook of RNA Biochemistry
Wiley-VCH (Publisher)
1st Edition
Published on 18. February 2005
Book
Hardback
XLII, 931 pages
978-3-527-30826-2 (ISBN)
Article exhausted; check for reprint
Description
An all-in-one compendium, bringing together novel methods hitherto only available in the primary literature. The experienced editors have gathered international authors for this ultimate in working knowledge. In more than 300 detailed protocols, the techniques covered are treated with users in mind, including practical advice and a "troubleshooting" section.
The broad scope of the book allows the side-by-side treatment of all pertinent laboratory methods, making this an invaluable guide for molecular biologists, biochemists and biotechnologists and everyone experimenting with RNA.
The broad scope of the book allows the side-by-side treatment of all pertinent laboratory methods, making this an invaluable guide for molecular biologists, biochemists and biotechnologists and everyone experimenting with RNA.
Reviews / Votes
"... is unique among the related publications. It is a wonderful guide to successful experimentation in the field of RNA research." Engineering in Life Sciences "...a true handbook that should not be missed in any laboratory engaged in RNA research. The text is concisely written, full of good ideas and the "troubleshooting" chapters will help to find ways out of deadlocks. I congratulate the authors to this handbook and recommend it to all RNA enthusiasts." Angewandte Chemie - IE "The book is helpful for molecular biologists, biochemists and biotechnologists and of interest to every researcher experimenting with RNA." NewDrugs "... these two volumes provide an in-depth introduction to methods for RNA analysis at all levels ..." Biomedical ChromatographyMore details
Edition
1., Auflage
Language
English
Place of publication
Weinheim
Germany
Target group
Professional and scholarly
Molekularbiologen, Biochemiker, Zellbiologen, Biotechnologen
Edition type
New edition
Illustrations
8
166 s/w Abbildungen, 26 s/w Tabellen, 8 farbige Abbildungen
Illustrations
Dimensions
Height: 24 cm
Width: 17 cm
Weight
2151 gr
ISBN-13
978-3-527-30826-2 (9783527308262)
Schweitzer Classification
Other editions
New editions

Roland K. Hartmann | Albrecht Bindereif | Astrid Schön
Handbook of RNA Biochemistry
Book
04/2014
2nd Edition
Wiley-VCH
€375.00
Article exhausted; check for reprint

Book
12/2008
1st Edition
Wiley-VCH
€99.00
Article is exhausted; no reprint
Persons
Roland K. Hartmann is Professor of Pharmaceutical Chemistry at the Philipps-Universität Marburg (Germany). He studied Biochemistry at the Freie Universität Berlin where in 1988 he received the Ernst Reuter award for outstanding Ph.D. theses. His research interests include natural ribozymes, particularly ribonuclease P, interactions of RNAs with proteins and small ligands, aptamers, antisense and RNA interference.
Albrecht Bindereif is Professor of Biochemistry at the University of Giessen (Germany) since 1999. He studied Biochemistry in Tübingen and at the University of California, Berkeley. His postdoctoral work was done in Michael Green's laboratory at Harvard University. His research interests focus on the mechanism and regulation of mRNA splicing, both in the mammalian system and in trypanosomes.
Astrid Schön received her PhD from the Institute of Biochemistry at the University of Würzburg, and was a graduate fellow and postdoctoral associate with Dieter Söll at Yale University. She is currently a lecturer at the Institute of Biochemistry, University of Leipzig (Germany). Her research is focused on RNA metabolism and RNA-protein interactions, and the evolution of complex RNA enzymes.
Eric Westhof is Professor of Biophysics at the Université Louis Pasteur in Strasbourg (France) since 1988. He studied in Liège and Regensburg and was a Fulbright-Hays Research Fellow at the University of Wisconsin with M. Sundaralingam. His research is centered on the relationships between sequence, structure, evolution and functions of RNA molecules.
Albrecht Bindereif is Professor of Biochemistry at the University of Giessen (Germany) since 1999. He studied Biochemistry in Tübingen and at the University of California, Berkeley. His postdoctoral work was done in Michael Green's laboratory at Harvard University. His research interests focus on the mechanism and regulation of mRNA splicing, both in the mammalian system and in trypanosomes.
Astrid Schön received her PhD from the Institute of Biochemistry at the University of Würzburg, and was a graduate fellow and postdoctoral associate with Dieter Söll at Yale University. She is currently a lecturer at the Institute of Biochemistry, University of Leipzig (Germany). Her research is focused on RNA metabolism and RNA-protein interactions, and the evolution of complex RNA enzymes.
Eric Westhof is Professor of Biophysics at the Université Louis Pasteur in Strasbourg (France) since 1988. He studied in Liège and Regensburg and was a Fulbright-Hays Research Fellow at the University of Wisconsin with M. Sundaralingam. His research is centered on the relationships between sequence, structure, evolution and functions of RNA molecules.
Content
RNA SYNTHESIS
Enyzmatic synthesis, ligation and modification
Chemical synthesis
STRUCTURE DETERMINATION
Sequence determination
Secondary and tertiary structure determination
Footprinting techniques
Identification of interacting proteins and nucleic acids
Nucleotide analog interference mapping
Atomic structure determination
Spectroscopic studies of RNA structure
GENOMICS & BIOINFORMATICS
Phylogenetic analysis
Structure prediction
Molecular dynamics simulation
RNA mining and RNomics
ANALYSIS OF RNA FUNCTION
Isolation and purification of RNA-binding proteins
Genetic analysis of RNA-binding proteins
Three-hybrid analysis to identify RNA-binding proteins
Analysis of mRNA splice variants
Confocal microscopy studies of intracellular localization
In vitro selection of ribozymes and aptamers
RNA INTERFERENCE
Strategies for in vivo RNAi studies
(partial contents)
Enyzmatic synthesis, ligation and modification
Chemical synthesis
STRUCTURE DETERMINATION
Sequence determination
Secondary and tertiary structure determination
Footprinting techniques
Identification of interacting proteins and nucleic acids
Nucleotide analog interference mapping
Atomic structure determination
Spectroscopic studies of RNA structure
GENOMICS & BIOINFORMATICS
Phylogenetic analysis
Structure prediction
Molecular dynamics simulation
RNA mining and RNomics
ANALYSIS OF RNA FUNCTION
Isolation and purification of RNA-binding proteins
Genetic analysis of RNA-binding proteins
Three-hybrid analysis to identify RNA-binding proteins
Analysis of mRNA splice variants
Confocal microscopy studies of intracellular localization
In vitro selection of ribozymes and aptamers
RNA INTERFERENCE
Strategies for in vivo RNAi studies
(partial contents)