Dynamic Properties of Biomolecular Assemblies
Published on 12. December 1989
Book
Hardback
376 pages
978-0-85186-896-7 (ISBN)
Description
This work seeks to cover recent advances in a range of techniques that can be regarded as "dynamics" (hydrodynamics, NMR, dynamic light scattering, fluorescence anisotropy decay and electro-optics) and their application to specific assemblies of biological macromolecules: assemblies involving proteins, nucleic acids and glycoconjugates. Some important advances in the capture and analysis of data (in many cases of the notoriously difficult "multi-exponential" type) are identified. "In vivo" assemblies of biological macromulecules do not always exist in a dilute solution environment - normally far from it - and some attention is paid to the dynamic properties of more concentrated dispersions.
More details
Series
Language
English
Place of publication
Cambridge
United Kingdom
Target group
College/higher education
Professional and scholarly
Illustrations
index
Dimensions
Height: 210 mm
Width: 148 mm
ISBN-13
978-0-85186-896-7 (9780851868967)
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Schweitzer Classification
Content
Part I Techniques: hydrodynamic properties of macromulecular assemblies, J.Garcia de la Torre; modelling the gross conformation of assemblies using hydrodynamics - the whole body approach, S.E.Harding; aggregation and elastic moduli of weakly interacting macromolecules, D.M.Heyes and J.R.Melrose; biological applications of solid state NMR; dynamic light scattering by partially-fluctuating media, P.N.Pusey; analysi of macromolecular structures in solution by electro - optical procedures, D.Porschke and J.Antoniewicz; fluorescence studies of protein-subunit interactions, M.Han, et al; maximum entropy data analysis of dynamic parameters from pulsed-fluorescent decays, A.K.Livesey and J.C.Brochon Part 2 Dynamics of protein, nucleic acid and protein-nucleic acid assemblies: an approach to the hydrodynamics of elastically linked protein oligomers, A.J.Rowe; laser light scattering determination of size and particle composition of -endotoxin crystals from "Bacillus thuringiensis", D.B.Sattelle et al; hydrodynamic and fluorescence analysis of a DNA binding protein and its interaction with DNA, G.G.Kneale; mechanisms of dynamic ordering in DNA solutions, V.A.Bloomfield; 15N NMR spectroscopy of DNA in the solid state, K.M.Morden and S.J.Opella. Part 3 Dynamics of glycoconjugates and membranes: conformational equilibria and dynamics of small carbohydrates - anomers, tautomers and rotamers, F.Franks; hydrodynamic modelling of complement, S.J.Perkins; flow properties of proteoglycan solutions, T.E.Hardingham et al; models for the macromolecular structure of mucus glycoproteins, J.K.Sheehan and I.Carlstedt; conformations and dynamics of saccarides, R.J.P.Williams and D.L.Fernandes; magnetic resonance studies of molecular dynamics at membrane surfaces, A.Watts; dynamic properties of model membranes by quasi-elastic light scattering, J.C.Earnshaw.