IgE Receptor (FceRI) Function in Mast Cells and Basophils
Published on 19. November 2013
Book
Paperback/Softback
XI, 292 pages
978-3-662-22024-5 (ISBN)
Description
The high affinity IgE receptor (FceRI) plays a central role in allergic diseases including asthma, allergic rhinitis, atopic dermatitis, food and drug allergy. Manipulating the function of this receptor is important for controlling the onset of allergic diseases. Written by leading scientists in the field, this book is the first comprehensive monograph to cover various aspects of FceRI structure, signal transduction and function. Thus, the book is valuable for researchers/students working on FceRI and on other receptors. In addition, clinicians who are concerned with broadening their knowledge of the FceRI role in allergic diseases will find this book useful.
More details
Series
Edition
Softcover reprint of the original 1st ed. 1997
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
41 s/w Abbildungen
XI, 292 p. 41 illus.
Dimensions
Height: 279 mm
Width: 210 mm
Thickness: 17 mm
Weight
755 gr
ISBN-13
978-3-662-22024-5 (9783662220245)
DOI
10.1007/978-3-662-22022-1
Schweitzer Classification
Other editions
Additional editions
Majed M. Hamawy
IgE Receptor (FceRI) Function in Mast Cells and Basophils
Book
02/1997
2nd Edition
Springer
€85.59
Article exhausted; check different version
Content
1. Fc?RI: Perspective.- 2. The Structural Basis of the Interaction of IgE and Fc?RI.- 3. Fc?RI-Induced Protein Tyrosine Phosphorylation.- 4. Role of Phospholipases, Protein Kinases and Calcium in Fc?RI-Induced Secretion.- 5. Role of GTP-Binding Proteins in Fc?RI Signaling.- 6. Phosphorylation of Serines and Threonines in Fc?RI-Mediated Responses in Mast Cells.- 7. Protein Tyrosine Phosphatases in Signaling Through the Fc?RI on Mast Cells and Basophils.- 8. Regulation and Roles of the Membrane, Cytoskeletal and Adhesive Responses of RBL-2H3 Rat Tumor Mast Cells to Fc?RI Crosslinking.- 9. Fc?RI-Mediated Cell Degranulation, Proliferation and Adhesion.- 10. Signal Transduction Pathways Regulating Arachidonic Acid Metabolite Generation Following Fc?RI Aggregation.- 11. Fc?RI-Induced Cytokine Production and Gene Expression.- 12. Regulation of Fc?RI Function by Integrins and Other Molecules on Mast Cells and Basophils.- 13. Signal Transduction Issues in Studies of Human Basophils and Mast Cells.