
The Amide Linkage
Structural Significance in Chemistry, Biochemistry, and Materials Science
Wiley (Publisher)
1st Edition
Published on 11. November 2002
Book
Paperback/Softback
XVI, 656 pages
978-0-471-42025-5 (ISBN)
Article exhausted; check different version
Description
Coverage of structure, bonding, and energetics of the amide bond, including electron density distribution, amide rotation, stereochemistry, spectroscopy, and thermochemistry.
* Specific applications to supramolecular and stereospecific synthesis.
* Key aspects of peptide and protein chemistry are discussed in terms of properties of the amide bond.
* Highlights how the amide linkage participates in the design of enzyme inhibitors, cyclic peptides, and antibacterial agents.
More details
Edition
1., Auflage
Language
English
Place of publication
New York
United States
Publishing group
John Wiley and Sons Ltd
Target group
College/higher education
Professional and scholarly
Dimensions
Height: 24.1 cm
Width: 15.5 cm
Thickness: 29 mm
Weight
936 gr
ISBN-13
978-0-471-42025-5 (9780471420255)
Schweitzer Classification
Other editions
Additional editions

Arthur Greenberg | Curt M. Breneman | Joel F. Liebman
The Amide Linkage
Structural Significance in Chemistry, Biochemistry, and Materials Science
Book
01/2000
1st Edition
Wiley
€366.50
Shipment within 10-20 days
Persons
ARTHUR GREENBERG, PhD, is Professor in the Department of Chemistry at the University of New Hampshire.
CURT M. BRENEMAN, PhD, is Professor in the Department of Chemistry at Rensselaer Polytechnic Institute.
JOEL F. LIEBMAN, PhD, is Professor in the Department of Chemistry and Biochemistry at the University of Maryland, Baltimore County.
Content
The Electron Density Distribution of Amides and Related Compounds (C. Breneman & M. Martinov).
Origin of the Amide Rotational Barrier (K. Wiberg).
The Amide Linkage as a Ligand-Its Properties and the Role of Distortion (A. Greenberg).
Studies in Amide Hydrolysis: The Acid, Base, and Water Reactions (R. Brown).
The Thermochemistry of Amides (J. Liebman, et al.).
Stereospecificity in the -Lactam (Aziridinone) Synthon (R. Hoffman).
-Lactams: Cyclic Amides of Distinction (A. Bose, et al.).
Sterically Hindered Twisted Amides (S. Yamada).
Photoelectron Spectroscopy of Amides and Lactams (P. Rademacher).
The Role of Amides in the Noncovalent Synthesis of Supramolecular Structures in Solution, at Interfaces, and in Solids (G. Palmore & J. MacDonald).
-Lactam Antibacterial Agents: Computational Chemistry Investigations (D. Boyd).
Three-Dimensional Design of Enzyme Inhibitors with Heterocyclic Amide Bond Mimics (R. Bohacek & W. Shakespeare).
Ab Initio Conformational Analysis of Protein Subunits: A Case Study of the Serine Diamide Model (A. Perczel & I. Csizmadia).
Gas-Phase Ion Chemistry of Amides, Peptides, and Proteins (C. Cassady).
-Sheet Interactions Between Proteins (S. Maitra & J. Nowick).
Head-to-Tail Cyclic Peptides and Cyclic Peptide Libraries (A. Spatola & P. Romanovskis).
From Crystal Structures of Oligopeptides to Protein Folding. The Importance of Peptide Bond-Side Chain Hyperconjugation (A. Cieplak).
Role of the Peptide Bond in Protein Structure and Folding (N. Kallenbach, et al.).
Index.