Cancer
M. F. Greaves(Author)
Oxford University Press
Published on 1. June 2000
Book
Hardback
288 pages
978-0-19-262835-0 (ISBN)
Description
Around one in three people will at some time in their lives be diagnosed with cancer. For Western societies relishing health, wealth, and longevity, its continued prominence is one of the greatest challenges to science. Cancer is extraordinarily diverse in its causation, symptoms, likelihood of effective treatment - in some sense, every patient's cancer is unique, and that is part of the problem. Mel Greaves explains why the old paradigms of infectious diseases or genetic disorders have proved fruitless, and claims that by looking at cancer in its evolutionary context, we can begin to answer some of the big questions in cancer that concern us all. Drawing on both ancient and more modern evolutionary legacies, he shows how human development has changed the rules of evolutionary games, trapping us in a nature-nurture mismatch.
Reviews / Votes
"Greaves shows an appreciable mastery of the issues, and does not try to obscure their complexity. He also shows a refreshing willingness to express his personal opinions on these issues, and the intellectual honesty to clearly acknowledge them as such. If you are looking for a thoughtful overview of the issues of evolution in cancer, The Evolutionary Legacy is a good place to start." Heredity, 88More details
Language
English
Place of publication
Oxford
United Kingdom
Illustrations
20 halftones, 20 line illustrations, index
ISBN-13
978-0-19-262835-0 (9780192628350)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Preface; PART I. CANCER: ANCIENT LEGACIES AND MODERN MYTHS; 1. Perplexed? You should be; 2. The King of Naples and other silent witnesses; 3. Questions and answers; PART II. EVOLVING CANCER; 4. Clones, clones, clones; 5. The way we are: risk and restraints; 6. How cancer cells play the winning game; 7. Green-eyed mutations?; 8. Blind chance - and ultimate extinction?; PART III. PARADOXES OF PROGRESS: INDECENT EXPOSURES; 9. Is cancer an evolutionary inevitability?; 10. And then you set fire to it?; 11. Women's troubles; 12. Men's troubles; 13. Cancer a deux; 14. Other ways of getting bugged; 15. Travelling light; 16. Dying for a living; 17. Collateral damage; 18. Finale: compounding risk with bad luck; PART IV. FINESSING THE CLONE; 19. Treatment: the blind marksman; 20. Epilogue: cancer in the 21st century; Index