
Mechanical Forces: Their Effects on Cells and Tissues
Their Effects on Cells and Tissues
Springer (Publisher)
Published on 17. July 1997
Book
Hardback
XII, 182 pages
978-3-540-62928-3 (ISBN)
Description
Animal Cell Culture nimal cell culture began in 1912 when Alexis Carrel grew bits of chick heart A in vitro by placing them into a drop of horse plasma. When the plasma clotted, it formed a solid surface into which the heart cells explanted. Left unattended, these cells died within several days. By regularly feeding the grow ing cells with aqueous extracts of whole chick embryos and periodically sub dividing them, Carrel was able to maintain the cells for extended periods. From these initial experiments, cell culture has expanded into an important component of biological research and commercial production. Animal cell culture is an important tool for the study of complex biologi cal systems. In vivo it is often impossible to target a treatment to one specific cell type or to adequately control the environment. For example, it is impos sible to selectively depolarize endothelial cells in vivo to determine the role of transmembrane potential in the transduction of fluid mechanical forces generated by blood flow to a biochemical response. Depolarizing all of the cells within the vascular system by injecting potassium chloride into the animal's bloodstream clearly is not an option, as it will lead to cardiac arrest.
More details
Series
Language
English
Place of publication
Heidelberg
Germany
Publishing group
Springer Berlin
Target group
College/higher education
Professional and scholarly
Illustrations
33
33 s/w Abbildungen
33 black & white illustrations, biography
Dimensions
Height: 23.5 cm
Width: 15.5 cm
Weight
440 gr
ISBN-13
978-3-540-62928-3 (9783540629283)
DOI
10.1007/978-3-662-03420-0
Schweitzer Classification
Other editions
Additional editions

Keith J. Gooch | Christopher J. Tennant
Mechanical Forces: Their Effects on Cells and Tissues
Book
12/2012
Springer
€53.49
Shipment within 7-9 days
Content
1. Introduction.- 2. Endothelial Cells.- 3. Bone Cells.- 4. Chondrocytes.- 5. Muscle Cells.- 6. Mechanotransduction.- 7. Production Systems.- 8. Overview.