
Omic Association Studies with R and Bioconductor
Chapman & Hall/CRC (Publisher)
1st Edition
Published on 18. December 2020
Book
Paperback/Softback
376 pages
978-0-367-72810-6 (ISBN)
Description
After the great expansion of genome-wide association studies, their scientific methodology and, notably, their data analysis has matured in recent years, and they are a keystone in large epidemiological studies. Newcomers to the field are confronted with a wealth of data, resources and methods. This book presents current methods to perform informative analyses using real and illustrative data with established bioinformatics tools and guides the reader through the use of publicly available data. Includes clear, readable programming codes for readers to reproduce and adapt to their own data.
Emphasises extracting biologically meaningful associations between traits of interest and genomic, transcriptomic and epigenomic data
Uses up-to-date methods to exploit omic data
Presents methods through specific examples and computing sessions
Supplemented by a website, including code, datasets, and solutions
Emphasises extracting biologically meaningful associations between traits of interest and genomic, transcriptomic and epigenomic data
Uses up-to-date methods to exploit omic data
Presents methods through specific examples and computing sessions
Supplemented by a website, including code, datasets, and solutions
Reviews / Votes
"This book is a good tool for self-learning analytical strategies for omics data. It requires previous knowledge of R and focuses on getting things done...I think the book would be a good reference for masters or PhD students that have to perform their analysis and need a starting point. Also, for the practicing statistician working with omics data."- Victor Moreno, ISCB News, July 2020
More details
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
College/higher education
Dimensions
Height: 234 mm
Width: 156 mm
Weight
720 gr
ISBN-13
978-0-367-72810-6 (9780367728106)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Juan R. Gonzalez | Alejandro Caceres
Omic Association Studies with R and Bioconductor
E-Book
06/2019
1st Edition
Chapman & Hall/CRC
€68.49
Available for download

Juan R. Gonzalez | Alejandro Caceres
Omic Association Studies with R and Bioconductor
E-Book
06/2019
1st Edition
Chapman & Hall/CRC
€68.49
Available for download

Juan R. Gonzalez | Alejandro Caceres
Omic Association Studies with R and Bioconductor
Book
06/2019
1st Edition
CRC Press
€172.00
Shipment within 10-20 days
Persons
Juan R. Gonzalez is an Associate Research Professor leading the Bioinformatics Research Group in Epidemiology at Barcelona Institute for Global Health. He has published extensively on methods and bioinformatics tools to detect structural variants from genomic data and to perform different types of omic association studies. Dr. Gonzalez is the author of a large number of R and Bioconductor packages including state-of-the-art libraries such as SNPassoc or MAD that have been used to discover new susceptibility genetic factor for complex diseases.
Alejandro Caceres is a Senior Statistician in the Bioinformatics Research Group in Epidemiology at Barcelona Institute for Global Health. He has large experience in developing new statistical methods to exploit genomic, transcriptomic and epigenomic data obtained from public repositories. Dr. Caceres is the author of several R and Bioconductor packages that have been used, for instance, to study the role of polymorphic genomic inversions in complex diseases or to investigate how the downregulation of chromosome Y may affect age-related diseases.
Alejandro Caceres is a Senior Statistician in the Bioinformatics Research Group in Epidemiology at Barcelona Institute for Global Health. He has large experience in developing new statistical methods to exploit genomic, transcriptomic and epigenomic data obtained from public repositories. Dr. Caceres is the author of several R and Bioconductor packages that have been used, for instance, to study the role of polymorphic genomic inversions in complex diseases or to investigate how the downregulation of chromosome Y may affect age-related diseases.
Content
1 Introduction 2 Case examples 3 Dealing with omic data in Bioconductor 4 Genetic association studies 5 Genomic variant studies 6 Adressing batch effects 7 Transcriptomic studies 8 Epigenomic studies 9 Exposomic analysis 10 Enrichment analysis 11 Multiomic data analysis