Advances in Metabolic Mapping Techniques for Brain Imaging of Behavioral and Learning Functions
Published on 20. November 2013
Book
Paperback/Softback
XXV, 527 pages
978-94-010-5202-3 (ISBN)
Description
In recent years, revolutionary technical advances have permitted neuroscientists to map the functioning of the brain in exquisite detail. Of interest are the new techniques that visually display cell energy metabolism which is coupled to functional brain activity in behaving animals.
This is the first book dealing with the application of 2-deoxyglucose and related metabolic mapping techniques for brain imaging of behavioral and learning functions. Quantitative autoradiographic techniques based on the use of exogenous markers include radiolabeled glucose and its analogs, especially 2-deoxyglucose and fluorodeoxyglucose. Other mapping techniques are based on the histochemical staining of endogenous metabolic markers such as cytochrome oxidase, as well as immunohistochemistry for expression of c-fos genes. In spite of the great potential capabilities of the new imaging techniques, relatively few neuroscientists are using this approach to study brain functions related to behavior. There is a need to review state-of-the-art applications of these methods in behavioral neuroscience, and to formulate recommendations for future research in this area. This book is intended to fulfill these needs by bringing together leading neuroscientists using metabolic mapping approaches to elucidate brain mechanisms of behavior. Discussions are not limited to one animal species, but they cover a broad range of vertebrates with unique behavioral capabilities.
This is the first book dealing with the application of 2-deoxyglucose and related metabolic mapping techniques for brain imaging of behavioral and learning functions. Quantitative autoradiographic techniques based on the use of exogenous markers include radiolabeled glucose and its analogs, especially 2-deoxyglucose and fluorodeoxyglucose. Other mapping techniques are based on the histochemical staining of endogenous metabolic markers such as cytochrome oxidase, as well as immunohistochemistry for expression of c-fos genes. In spite of the great potential capabilities of the new imaging techniques, relatively few neuroscientists are using this approach to study brain functions related to behavior. There is a need to review state-of-the-art applications of these methods in behavioral neuroscience, and to formulate recommendations for future research in this area. This book is intended to fulfill these needs by bringing together leading neuroscientists using metabolic mapping approaches to elucidate brain mechanisms of behavior. Discussions are not limited to one animal species, but they cover a broad range of vertebrates with unique behavioral capabilities.
More details
Series
Edition
Softcover reprint of the original 1st ed. 1992
Language
English
Place of publication
Dordrecht
Netherlands
Target group
Professional and scholarly
Research
Illustrations
1 farbige Abbildung, 95 s/w Abbildungen
XXV, 527 p. 96 illus., 1 illus. in color.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 30 mm
Weight
832 gr
ISBN-13
978-94-010-5202-3 (9789401052023)
DOI
10.1007/978-94-011-2712-7
Schweitzer Classification
Other editions
Additional editions
Francisco Gonzalez-Lima | Th. Finkenstädt | Henning Scheich
Advances in Metabolic Mapping Techniques for Brain Imaging of Behavioral and Learning Functions
E-Book
12/2012
Springer
€53.49
Available for download
Francisco Gonzalez-Lima | Th. Finkenstadt | Henning Scheich
Advances in Metabolic Mapping Techniques for Brain Imaging of Behavioral and Learning Functions
Proceedings of the NATO Advanced Research Workshop, Austin, Texas, U.S.A., November 7-9, 1991
Book
09/1992
Kluwer Academic Publishers
€89.13
Article exhausted; check different version
Content
I: Techniques.- Imaging Techniques in Studies of Neural Functions.- Brain Imaging of Auditory Learning Functions in Rats: Studies with Fluorodeoxyglucose Autoradiography and Cytochrome Oxidase Histochemistry.- Mapping Sensorimotor Pathways in Rat Brain Using 2-Deoxyglucose Autoradiography and C-Fos Immunocytochemistry.- Brain Metabolic Mapping and Behavior: Assessing the Effects of Early Developmental Experiences in Adult Animals.- High Resolution Autoradiographic Imaging of Brain Activity Patterns With 2-Deoxyglucose: Regional Topographic and Cellular Analysis.- Metabolic Mapping in the Hippocampus. Patterns of (14C)2-Deoxyglucose Uptake Within Different Fields of the Hippocampal Slice.- Covariance Analysis of Functional Interactions in the Brain Using Metabolic and Blood Flow Data.- The Application of Structural Modeling to Metabolic Mapping of Functional Neural Systems.- II: Application.- A 2-DG Analysis of the Effects of Monocular Deprivation on the Rat Visual System.- Development of Sound Representation in the Auditory Cortex of Tree Shrews (Tupaia Belangeri): A [14C]-2-DG Study.- Integration of Circadian and Visual Function in Mammals and Birds: Brain Imaging and the Role of Melatonin in Biological Clock Regulation.- Functional Correlates of Acute Prolonged Pain in the Rat Central Nervous System: 2-DG Studies.- Brain Systems Involved in Depressed Behaviors: Corroboration from Different Metabolic Mapping Studies..- 2-DG and Neuroethology: Metabolic Mapping of Brain Activity During Species-Typical Sexual and Aggressive Behaviors.- Investigations into Time-Dependent Metabolic Changes During Memory Processing in the Mouse Brain Using (14C)-Deoxyglucose and (14C)-Glucose.- Localization of Learning-Related Metabolic Changes in Brain Structures of Common Toads: A 2-DG-Study.- Learning-Related Plasticity of Gerbil Auditory Cortex: Feature Maps versus Meaning Maps.- III: Discussions.- Discussions on Advances in Metabolic Mapping Techniques.- Discussions on Brain Imaging of Behavioral Functions.- Discussions on Brain Imaging of Learning Functions.