Modeling Protein Evolution and Its Bioinformatics Applications

While there are many books available on bioinformatics and on molecular evolution, there are none that adequately address the interaction of these two areas. Filling this gap, this book covers both the fundamentals of evolutionary theory and its application to bioinformatics. It gives readers a broad overview of the nature of molecular evolution, techniques that have been developed for modelling this evolution, tools to interpret biological information in an evolutionary context, and software that has and is being developed to analyze the evolutionary processes. The book does not provide detailed coverage of the mathematical machinery, but provides just enough information to make it accessible.