From Genetics to Quality of Life
The Optimal Treatment and Management of Asthma. Proceedings of the XVth World Congress of Asthmology
Published in April 1996
Book
Hardback
240 pages
978-0-88937-169-9 (ISBN)
Description
This volume considers the latest theories and current knowledge of asthma and is for health professionals involved in the care and treatment of asthma patients. The key group behind this book is Interasthma, a a society which has been functioning for over 40 years and which is focused on the prevention and treatment of the disease. As a result, asthma specialist from around the world have contributed their latest medical insights, including what are considered to be the most effective clinical and management techniques of direct assistance to asthma patients and their families.
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Content
Part 1 From epidemiology to genetics and treatment: candidate locus approach to the genetics of asthma and atopy; genetic studies of IgE responsiveness and asthma; polygenes, asthma and atopy. Part 2 Basic mechanisms of asthma: asthma - relationships between airway inflammatory mediators and lung function; basic mechanisms in asthma - endothelial cells; implications of bronchial epithelial cells in asthma; cell adhesion molecules; growth factors in asthma; corticosteroid resistant asthma; mechanism of aspirin-induced asthma; regulation of human IgE synthesis. Part 3 Allergy and air pollution: sensitization of young children; air pollutants and allergic sensitization; air pollution and asthma - the role of epithelial cells. Part 4 "Infectious " asthma: the role of respiratory infections in asthma; viral infections in children with existing asthma; treatment of virus-induced asthma in childhood - effect on long-term outcome; bacterial sinusitis and its relationship to lower airway hyperreactivity; importance of bacterial infection in the aetiopathogenesis of bronchial asthma. Part 5 Optimum asthma management: long term follow-up of asthmatic patients; new views on monitoring asthmatic patients; from childhood to adulthood - predictive factors; anti-inflammatory treatments for asthma - past, present, future; the role of education in asthma management. Part 6 New treatments: 5-lipoxygenase inhibition in the treatment of asthma; the therapeutic potential of PDE4 inhibitors in asthma; transcription factors and asthma; a new place for theophylline in asthma; IL-5 in pulmonary inflammation; IgE modulation - potential for anti-IgE therapy in asthmatic disease; asthma and immunotherapy; peptide downregulation of the immune response. Part 7 Quality of life: assessment of health-related quality of life in asthma and rhinitis using disease-specific instruments; genetic scales of quality of life in asthma and rhinitis; can management of asthma reduce costs?