
The Fetal Matrix: Evolution, Development and Disease
Evolution, Development and Disease
Cambridge University Press
Published on 18. November 2004
Book
Hardback
268 pages
978-0-521-83457-5 (ISBN)
Article exhausted; check for reprint
Description
New discoveries reveal how crucial interactions which determine our destiny occur before birth, when our genes interact with their environment as the embryo and fetus develop. These processes - in the matrix of the womb - are evolutionary echoes of mechanisms which allowed our hunter-gatherer ancestors to survive. These exciting insights into predictive adaptive responses suggest new ways of protecting the health of the fetus, infant and adult. If inappropriate they can trigger obesity, diabetes and heart disease, formerly thought to result solely from adult lifestyle. The new concepts in this book are crucial to understanding the daunting public health burden in societies undergoing rapid transition from poverty to affluence. They add an important new dimension to evolutionary theory. Synthesising developmental biology, evolutionary history, medical science, public health and social policy, this is a ground-breaking and fascinating account by two of the world's leading pioneers in this important emerging field.
Reviews / Votes
'Gluckman and Hanson argue that the interaction between mammals and their environment while in the womb irreversibly affects their future development, what they call a 'predictive adaptive response'. It also has huge health implications for the rest of their lives. The authors are persuasive, and their findings have relevance for health policy everywhere. If maternal well-being affects the lifelong health of the offspring, it makes good sense to ensure that mothers are always well cared for.' New Scientist 'In an ideal world The Fetal Matrix would be taken more seriously than any other book on health and nutrition purlished in the past year.' FT Magazine 'Those seeking an alternative to the current preventive approaches focused on healthy choices by adults should certainly read Gluckman and Hanson's book. The book itself provides a clear description of the origin and development of a provocative and truly original idea.' Journal of the Royal Society of Medicine 'The Fetal Matrix by Peter Gluckman and Mark Hanson is a fascinating and important book about the responses of the mammalian fetus to its environment ... a thought-provoking account of a topic in which developmental biology, physiology and clinical medicine intersect.' Nature 'The biological interpretation of disease and health is a topic in need of serious attention and wider dissemination. In The Fetal Matrix, Gluckman and Hanson have made a very interesting contribution to this enterprise. ... they have introduced, in a very readable fashion, an idea that is likely to receive further attention.' BiologistMore details
Language
English
Place of publication
Cambridge
United Kingdom
Target group
College/higher education
Professional and scholarly
Illustrations
3 Halftones, unspecified; 15 Line drawings, unspecified
Dimensions
Height: 255 mm
Width: 181 mm
Thickness: 19 mm
Weight
700 gr
ISBN-13
978-0-521-83457-5 (9780521834575)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions

Peter Gluckman | Mark Hanson
The Fetal Matrix: Evolution, Development and Disease
Evolution, Development and Disease
Book
11/2004
Cambridge University Press
€93.00
Shipment within 15-20 days
Additional editions

Peter Gluckman | Mark Hanson
The Fetal Matrix: Evolution, Development and Disease
Evolution, Development and Disease
E-Book
12/2007
1st Edition
Cambridge University Press
€67.99
Available for download

Peter Gluckman | Mark Hanson
The Fetal Matrix: Evolution, Development and Disease
Evolution, Development and Disease
Book
11/2004
Cambridge University Press
€93.00
Shipment within 15-20 days
Persons
In 2004, Dr Peter Gluckman was named 'New Zealander of the Year' by the New Zealand Herald. The newspaper recognized him for 'a long career of achievement that has brought life-saving developments in medicine and demonstrated an ability to produce world-leading scientific research in New Zealand.
Content
1. Shaping our destiny: genes, environment and their interactions; 2. Mother and fetus; 3. Fetal choices; 4. Predictive adaptive responses and human diseases; 5. Obesity, diabetes and other diseases; 6. The biology of predictive adaptive responses; 7. Predictive adaptive responses - critical processes in evolution; 8. Evolutionary echoes and the human camel; 9. Improving human health; 10. Fetal futures.